دورية أكاديمية
3D Specimen Scanning and Mapping in Musculoskeletal Oncology: A Feasibility Study.
| العنوان: | 3D Specimen Scanning and Mapping in Musculoskeletal Oncology: A Feasibility Study. |
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| المؤلفون: | Colazo JM; School of Medicine, Vanderbilt University, Nashville, TN, USA., Prasad K; Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Miller A; Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Sharif K; School of Medicine, Vanderbilt University, Nashville, TN, USA., Aweeda M; Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Fassler C; Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Singh R; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Schwartz HS; Division of Musculoskeletal Oncology, Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Lawrenz JM; Division of Musculoskeletal Oncology, Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Holt GE; Division of Musculoskeletal Oncology, Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Topf MC; Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA. michael.topf@vumc.org. |
| المصدر: | Annals of surgical oncology [Ann Surg Oncol] 2024 Mar; Vol. 31 (3), pp. 2051-2060. Date of Electronic Publication: 2023 Dec 22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: United States NLM ID: 9420840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4681 (Electronic) Linking ISSN: 10689265 NLM ISO Abbreviation: Ann Surg Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2005- : New York, NY : Springer Original Publication: New York, NY : Raven Press, c1994- |
| مواضيع طبية MeSH: | Surgery, Computer-Assisted*/methods , Soft Tissue Neoplasms*, Humans ; Feasibility Studies ; Prognosis ; Margins of Excision ; Retrospective Studies |
| مستخلص: | Background: Surgical resection is the primary treatment for bone and soft tissue tumors. Negative margin status is a key factor in prognosis. Given the three-dimensional (3D) anatomic complexity of musculoskeletal tumor specimens, communication of margin results between surgeons and pathologists is challenging. We sought to perform ex vivo 3D scanning of musculoskeletal oncology specimens to enhance communication between surgeons and pathologists. Methods: Immediately after surgical resection, 3D scanning of the fresh specimen is performed prior to frozen section analysis. During pathologic grossing, whether frozen or permanent, margin sampling sites are annotated on the virtual 3D model using computer-aided design (CAD) software. Results: 3D scanning was performed in seven cases (six soft tissue, one bone), with specimen mapping on six cases. Intraoperative 3D scanning and mapping was performed in one case in which the location of margin sampling was shown virtually in real-time to the operating surgeon to help achieve a negative margin. In six cases, the 3D model was used to communicate final permanent section analysis. Soft tissue, cartilage, and bone (including lytic lesions within bone) showed acceptable resolution. Conclusions: Virtual 3D scanning and specimen mapping is feasible and may allow for enhanced documentation and communication. This protocol provides useful information for anatomically complex musculoskeletal tumor specimens. Future studies will evaluate the effect of the protocol on positive margin rates, likelihood that a re-resection contains additional malignancy, and exploration of targeted adjuvant radiation protocols using a patient-specific 3D specimen map. (© 2023. Society of Surgical Oncology.) |
| التعليقات: | Comment in: Ann Surg Oncol. 2024 Mar;31(3):2061-2062. (PMID: 38170410) |
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| فهرسة مساهمة: | Keywords: 3D scanning; Bone and soft tissue tumor; Musculoskeletal oncology; Musculoskeletal tumor; Orthopedic oncology; Sarcoma; Surgical margins |
| تواريخ الأحداث: | Date Created: 20231222 Date Completed: 20240208 Latest Revision: 20240409 |
| رمز التحديث: | 20240409 |
| DOI: | 10.1245/s10434-023-14757-w |
| PMID: | 38133863 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1534-4681 |
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| DOI: | 10.1245/s10434-023-14757-w |