دورية أكاديمية
Preoperative Noninvasive Evaluation of Tumor Budding in Rectal Cancer Using Multiparameter MRI Radiomics.
| العنوان: | Preoperative Noninvasive Evaluation of Tumor Budding in Rectal Cancer Using Multiparameter MRI Radiomics. |
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| المؤلفون: | Peng L; Department of Medical Imaging, The Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China (L.P., D.W., Z.Z., H.Z., L.Z.)., Wang D; Department of Medical Imaging, The Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China (L.P., D.W., Z.Z., H.Z., L.Z.); School of Medicine, Jiangsu University, Zhenjiang, 212001, China (D.W., X.C., J.X.)., Zhuang Z; Department of Medical Imaging, The Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China (L.P., D.W., Z.Z., H.Z., L.Z.)., Chen X; School of Medicine, Jiangsu University, Zhenjiang, 212001, China (D.W., X.C., J.X.)., Xue J; School of Medicine, Jiangsu University, Zhenjiang, 212001, China (D.W., X.C., J.X.)., Zhu H; Department of Medical Imaging, The Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China (L.P., D.W., Z.Z., H.Z., L.Z.)., Zhang L; Department of Medical Imaging, The Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China (L.P., D.W., Z.Z., H.Z., L.Z.). Electronic address: tianchen861@ujs.edu.cn. |
| المصدر: | Academic radiology [Acad Radiol] 2024 Jun; Vol. 31 (6), pp. 2334-2345. Date of Electronic Publication: 2023 Dec 21. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Association Of University Radiologists Country of Publication: United States NLM ID: 9440159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4046 (Electronic) Linking ISSN: 10766332 NLM ISO Abbreviation: Acad Radiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Reston Va : Association Of University Radiologists Original Publication: Reston, VA : Association of University Radiologists, c1994- |
| مواضيع طبية MeSH: | Multiparametric Magnetic Resonance Imaging*/methods , Rectal Neoplasms*/diagnostic imaging , Rectal Neoplasms*/pathology, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Contrast Media ; Diffusion Magnetic Resonance Imaging/methods ; Preoperative Care/methods ; Radiomics ; Retrospective Studies |
| مستخلص: | Rationale and Objectives: To assess the value of a multiparametric magnetic resonance imaging (MRI)-based model integrating radiomics features with clinical and MRI semantic features for preoperative evaluation of tumor budding (TB) in rectal cancer. Materials and Methods: A total of 120 patients with pathologically confirmed rectal cancer were retrospectively analyzed. The patients were randomized into training and validation cohorts in a 6:4 ratio. Radiomics features were extracted and selected from preoperative T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and contrast-enhanced T1-weighted imaging (T1CE) sequences, after which the corresponding radiomics score (RS) was calculated, and the radiomics models (T2WI model, DWI model, and T1CE model) were constructed. Logistic regression analysis was selected to develop a combined model integrated RS Results: Seven features were extracted and selected from each T2WI, DWI, and T1CE sequence to calculate the corresponding RS and construct the corresponding radiomics model. MRI reported N stage was an independent risk factor for TB. The area under the ROC curve of the combined model was 0.961 and 0.891 in the training and validation cohorts, respectively. The combined model showed better performance than the other models. DCA showed that the net benefit of the combined model was better than that of the other models in the vast majority of threshold probabilities. Conclusion: A combined model integrating radiomics features and MRI semantic features allows for noninvasive preoperative evaluation of TB grading in patients with rectal cancer. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: MRI; Radiomics; Rectal cancer; Tumor budding |
| المشرفين على المادة: | 0 (Contrast Media) |
| تواريخ الأحداث: | Date Created: 20231222 Date Completed: 20240629 Latest Revision: 20240819 |
| رمز التحديث: | 20240820 |
| DOI: | 10.1016/j.acra.2023.11.023 |
| PMID: | 38135624 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1878-4046 |
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| DOI: | 10.1016/j.acra.2023.11.023 |