دورية أكاديمية
Sex, Endothelial Cell Functions, and Peripheral Artery Disease.
العنوان: | Sex, Endothelial Cell Functions, and Peripheral Artery Disease. |
---|---|
المؤلفون: | Cartland SP; Heart Research Institute, The University of Sydney, Sydney, NSW 2042, Australia., Stanley CP; Heart Research Institute, The University of Sydney, Sydney, NSW 2042, Australia., Bursill C; South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide, SA 5005, Australia., Passam F; Faculty of Health and Medicine, The University of Sydney, Sydney, NSW 2050, Australia., Figtree GA; Faculty of Health and Medicine, The University of Sydney, Sydney, NSW 2050, Australia.; Kolling Institute of Medical Research, Sydney, NSW 2064, Australia., Patel S; Heart Research Institute, The University of Sydney, Sydney, NSW 2042, Australia.; Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia., Loa J; Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia., Golledge J; Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University, Townsville, QLD 4811, Australia.; Department of Vascular and Endovascular Surgery, The Townsville University Hospital, Townsville, QLD 4814, Australia., Robinson DA; Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia., Aitken SJ; Faculty of Health and Medicine, The University of Sydney, Sydney, NSW 2050, Australia.; Concord Institute of Academic Surgery, Concord Repatriation General Hospital, Sydney, NSW 2139, Australia., Kavurma MM; Heart Research Institute, The University of Sydney, Sydney, NSW 2042, Australia. |
المصدر: | International journal of molecular sciences [Int J Mol Sci] 2023 Dec 13; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 13. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI, [2000- |
مواضيع طبية MeSH: | Peripheral Arterial Disease*/therapy , Atherosclerosis*, Male ; Humans ; Female ; Lower Extremity/blood supply ; Intermittent Claudication ; Endothelial Cells ; Risk Factors |
مستخلص: | Peripheral artery disease (PAD) is caused by blocked arteries due to atherosclerosis and/or thrombosis which reduce blood flow to the lower limbs. It results in major morbidity, including ischemic limb, claudication, and amputation, with patients also suffering a heightened risk of heart attack, stroke, and death. Recent studies suggest women have a higher prevalence of PAD than men, and with worse outcomes after intervention. In addition to a potential unconscious bias faced by women with PAD in the health system, with underdiagnosis, and lower rates of guideline-based therapy, fundamental biological differences between men and women may be important. In this review, we highlight sexual dimorphisms in endothelial cell functions and how they may impact PAD pathophysiology in women. Understanding sex-specific mechanisms in PAD is essential for the development of new therapies and personalized care for patients with PAD. |
References: | Endocrinol Metab Clin North Am. 2013 Jun;42(2):227-53. (PMID: 23702399) Diabetes Res Clin Pract. 2019 Nov;157:107843. (PMID: 31518657) Arterioscler Thromb Vasc Biol. 1996 Jan;16(1):160-4. (PMID: 8548417) Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H897-H909. (PMID: 29932772) Arch Phys Med Rehabil. 2008 Mar;89(3):422-9. (PMID: 18295618) Aust J Gen Pract. 2020 May;49(5):239-244. (PMID: 32416650) Circulation. 2020 Nov 10;142(19):1848-1862. (PMID: 32929989) Cardiovasc Ther. 2020 May 19;2020:2342837. (PMID: 32547635) Biol Sex Differ. 2017 Oct 24;8(1):33. (PMID: 29065927) Cell Calcium. 2012 May;51(5):402-10. (PMID: 22361139) Int J Mol Sci. 2022 Nov 29;23(23):. (PMID: 36499242) Ther Adv Cardiovasc Dis. 2022 Jan-Dec;16:17539447221096940. (PMID: 35583375) Circulation. 2000 Mar 7;101(9):1007-12. (PMID: 10704168) Vasc Med. 2010 Jun;15(3):181-8. (PMID: 20385711) Redox Biol. 2023 Jun;62:102681. (PMID: 37003179) Thromb Haemost. 1998 Apr;79(4):736-40. (PMID: 9569183) Front Genet. 2021 Feb 17;12:590377. (PMID: 33679877) Front Cardiovasc Med. 2021 Aug 30;8:736303. (PMID: 34527715) Sci Rep. 2017 Aug 29;7(1):9612. (PMID: 28852041) Atherosclerosis. 2019 Nov;290:37-43. (PMID: 31561090) Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):143-153. (PMID: 29097367) Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2027-34. (PMID: 21398592) Front Cardiovasc Med. 2021 Aug 27;8:704106. (PMID: 34513948) Sci Rep. 2020 Jul 23;10(1):12367. (PMID: 32704153) Thromb Res. 1986 Dec 15;44(6):837-47. (PMID: 3798423) Circulation. 1997 Apr 15;95(8):2068-74. (PMID: 9133517) Circ Res. 2022 Feb 18;130(4):496-511. (PMID: 35175843) Sci Rep. 2015 May 11;5:10003. (PMID: 25961501) Thromb Haemost. 1995 Nov;74(5):1271-5. (PMID: 8607108) Nitric Oxide. 2019 Nov 1;92:1-10. (PMID: 31369814) J Am Heart Assoc. 2020 Jul 21;9(14):e014726. (PMID: 32654613) Eur Heart J Qual Care Clin Outcomes. 2023 Jun 21;9(4):342-350. (PMID: 36882190) Biol Sex Differ. 2021 Jan 7;12(1):7. (PMID: 33413676) Arterioscler Thromb Vasc Biol. 1998 Jun;18(6):961-7. (PMID: 9633938) J Vasc Surg. 2017 May;65(5):1504-1514.e11. (PMID: 28024849) Front Pharmacol. 2020 Dec 17;11:587221. (PMID: 33390959) J Am Podiatr Med Assoc. 2008 Nov-Dec;98(6):489-93. (PMID: 19017860) Eur J Vasc Endovasc Surg. 2003 Jan;25(1):6-15. (PMID: 12525805) Sci Transl Med. 2019 Nov 6;11(517):. (PMID: 31694925) Eur J Pharmacol. 2000 Sep 22;404(3):341-51. (PMID: 10996599) J Vasc Surg. 2007 Jun;45(6):1185-91. (PMID: 17543683) Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):390-400. (PMID: 33176447) Molecules. 2022 Apr 12;27(8):. (PMID: 35458670) Physiol Rep. 2020 Jan;8(2):e14351. (PMID: 31960625) Circ Res. 2002 Mar 8;90(4):413-9. (PMID: 11884370) Redox Biol. 2021 Oct;46:102108. (PMID: 34438260) Atherosclerosis. 2019 Dec;291:99-106. (PMID: 31706078) Eur J Pharmacol. 2008 Dec 28;601(1-3):111-7. (PMID: 18996368) PLoS One. 2019 Nov 27;14(11):e0225771. (PMID: 31774869) Thromb Res. 2018 Aug;168:156-163. (PMID: 30064688) PLoS One. 2023 Oct 18;18(10):e0292083. (PMID: 37851596) J Am Coll Cardiol. 2018 Oct 30;72(18):2152-2163. (PMID: 30166084) Arterioscler Thromb Vasc Biol. 2020 Aug;40(8):1808-1817. (PMID: 32580632) Diabetes Care. 2019 Jan;42(1):50-54. (PMID: 30409811) Nat Rev Immunol. 2016 Oct;16(10):626-38. (PMID: 27546235) BMJ. 2018 Feb 1;360:j5842. (PMID: 29419394) Elife. 2021 Nov 29;10:. (PMID: 34842136) J Am Heart Assoc. 2019 Jan 22;8(2):e010849. (PMID: 30663486) N Engl J Med. 2020 Nov 19;383(21):2090-2091. (PMID: 33207109) J Vasc Surg. 2012 Aug;56(2):387-95; discussion 395. (PMID: 22633420) Am J Physiol Heart Circ Physiol. 2018 Nov 1;315(5):H1287-H1292. (PMID: 30095998) Lancet. 2013 Oct 19;382(9901):1329-40. (PMID: 23915883) Am J Physiol Heart Circ Physiol. 2010 Apr;298(4):H1146-54. (PMID: 20139324) Vasc Med. 2015 Oct;20(5):424-31. (PMID: 26240075) FEBS J. 2018 Apr;285(7):1359-1371. (PMID: 29474747) Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1569-H1588. (PMID: 30216121) FASEB J. 2021 May;35(5):e21480. (PMID: 33788962) Catheter Cardiovasc Interv. 2009 May 1;73(6):719-24. (PMID: 19213068) J Clin Pharm Ther. 2021 Apr;46(2):328-332. (PMID: 33052628) Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7475-9. (PMID: 7543683) Lancet Diabetes Endocrinol. 2018 Jul;6(7):538-546. (PMID: 29752194) Reproduction. 2018 Dec;156(6):559-567. (PMID: 30328349) Trends Cardiovasc Med. 2016 May;26(4):297-303. (PMID: 26877187) Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H725-35. (PMID: 21193584) Adv Pharmacol. 2016;77:307-60. (PMID: 27451102) J Physiol. 2018 Sep;596(17):3929-3949. (PMID: 29885204) J Surg Res. 2012 Dec;178(2):1022-8. (PMID: 22632940) PLoS One. 2020 Apr 9;15(4):e0231267. (PMID: 32271800) J Am Coll Cardiol. 2019 Jul 30;74(4):498-507. (PMID: 31345423) Cardiovasc Diabetol. 2003 Oct 04;2:12. (PMID: 14609437) J Vasc Surg. 2015 May;61(5):1249-57. (PMID: 24703977) JAMA. 2006 Mar 22;295(12):1420-7. (PMID: 16551714) J Am Heart Assoc. 2014 Mar 13;3(2):e000651. (PMID: 24627420) Endocr Rev. 2001 Feb;22(1):36-52. (PMID: 11159815) Blood Coagul Fibrinolysis. 2000 Jan;11(1):43-50. (PMID: 10691098) Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1499-H1518. (PMID: 30192631) J Clin Med. 2021 Feb 22;10(4):. (PMID: 33671744) Stroke. 2009 May;40(5):1827-33. (PMID: 19286591) Eur J Vasc Endovasc Surg. 2010 Mar;39(3):330-2. (PMID: 19889554) Brain Res. 2016 Sep 1;1646:494-503. (PMID: 27350079) Clin Sci (Lond). 2003 Apr;104(4):397-404. (PMID: 12653684) BMC Cardiovasc Disord. 2011 Jun 30;11:39. (PMID: 21718516) PLoS One. 2016 Jan 22;11(1):e0147067. (PMID: 26799933) Vasc Med. 2015 Feb;20(1):51-9. (PMID: 25659653) Front Cardiovasc Med. 2022 Nov 16;9:1054576. (PMID: 36465438) N Engl J Med. 1996 Jan 18;334(3):150-4. (PMID: 8531969) FASEB J. 2021 Sep;35(9):e21840. (PMID: 34423881) Atherosclerosis. 2015 Mar;239(1):260-7. (PMID: 25634157) Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):1982-1989. (PMID: 32673526) Circulation. 2021 Aug 31;144(9):e171-e191. (PMID: 34315230) Exp Neurol. 2014 Sep;259:16-27. (PMID: 24560819) J Am Coll Cardiol. 1994 Aug;24(2):471-6. (PMID: 8034885) PLoS One. 2019 Sep 3;14(9):e0221566. (PMID: 31479468) Circ Res. 2023 May 26;132(11):1428-1443. (PMID: 37154037) Atherosclerosis. 2004 Jan;172(1):95-105. (PMID: 14709362) Br J Pharmacol. 2003 Dec;140(7):1193-200. (PMID: 14597598) |
فهرسة مساهمة: | Keywords: endothelial cell dysfunction; peripheral artery disease; sex differences |
تواريخ الأحداث: | Date Created: 20231223 Date Completed: 20231225 Latest Revision: 20231225 |
رمز التحديث: | 20231225 |
مُعرف محوري في PubMed: | PMC10744086 |
DOI: | 10.3390/ijms242417439 |
PMID: | 38139267 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1422-0067 |
---|---|
DOI: | 10.3390/ijms242417439 |