دورية أكاديمية
Comparing a 19-gauge fine-needle biopsy needle with a 22-gauge fine-needle biopsy needle for EUS-guided liver biopsy sampling: a prospective randomized study.
| العنوان: | Comparing a 19-gauge fine-needle biopsy needle with a 22-gauge fine-needle biopsy needle for EUS-guided liver biopsy sampling: a prospective randomized study. |
|---|---|
| المؤلفون: | Diehl DL; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Sangwan V; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Johal AS; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Khara HS; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Confer B; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA. |
| المصدر: | Gastrointestinal endoscopy [Gastrointest Endosc] 2024 Jun; Vol. 99 (6), pp. 931-937. Date of Electronic Publication: 2023 Dec 21. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial; Comparative Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mosby Yearbook Country of Publication: United States NLM ID: 0010505 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6779 (Electronic) Linking ISSN: 00165107 NLM ISO Abbreviation: Gastrointest Endosc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: St Louis, Mo : Mosby Yearbook Original Publication: Denver. |
| مواضيع طبية MeSH: | Endoscopic Ultrasound-Guided Fine Needle Aspiration*/instrumentation , Endoscopic Ultrasound-Guided Fine Needle Aspiration*/methods , Needles* , Liver*/pathology, Humans ; Female ; Middle Aged ; Male ; Prospective Studies ; Adult ; Aged ; Liver Neoplasms/pathology ; Biopsy, Large-Core Needle/instrumentation ; Biopsy, Large-Core Needle/methods ; Liver Diseases/pathology |
| مستخلص: | Background and Aims: EUS-guided liver biopsy (EUS-LB) sampling is being increasingly used. We performed a prospective randomized trial to compare specimen adequacy of a 19-gauge fine-needle biopsy (FNB) needle with a 22-gauge FNB Franseen tip needle for EUS-LB sampling. Methods: Forty-two consecutive patients referred for EUS-LB sampling were prospectively randomized to a 19-gauge or 22-gauge FNB needle. When the specimen with the 22-gauge needle was macroscopically inadequate, an additional pass with the 19-gauge needle was done. Bilobar EUS-LB sampling was performed with heparinized wet suction using 1 pass and 3 actuations per lobe. Descriptive statistics were computed for all variables. Results: Biopsy sampling was performed for abnormal liver enzymes in 95.5% of patients (57% women; average age, 51 years). Five patients undergoing sampling with the 22-gauge FNB needle had macroscopically inadequate specimens and required additional biopsy sampling with the 19-gauge FNB needle. Mean preprocessing length of the longest tissue core was 21.5 ± 6.3 mm with a 19-gauge FNB needle compared with 9.4 ± 5.5 mm with the 22-gauge FNB needle (P < .001). Postprocessing specimens were significantly longer with 19-gauge than with 22-gauge FNB needles (17.4 mm vs 6.8, P < .001). There were no adverse events, and postprocedure pain and discomfort was similar in both groups (14% for 19-gauge vs 10% for 22-gauge, P = .99). Conclusions: Liver core biopsy sampling using the 19-gauge FNB needle is superior to the 22-gauge FNB needle in terms of length of longest core and aggregate specimen length. Considerably more fragmentation of the 22-gauge cores occurs during tissue processing. No increased postprocedure pain or AEs were found with the 19-gauge needle. A 19-gauge FNB needle is preferred to the 22-gauge FNB needle for EUS-LB. (Clinical trial registration number: NCT04806607.). Competing Interests: Disclosure The following authors disclosed financial relationships: D. L. Diehl: Consultant for Boston Scientific, Olympus, and Cook Medical. H. S. Khara: Consultant for Boston Scientific, Olympus, and Medtronic. B. Confer: Speaker for Boston Scientific; consultant for Exact Sciences. All other authors disclosed no financial relationships. (Copyright © 2024 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.) |
| سلسلة جزيئية: | ClinicalTrials.gov NCT04806607 |
| تواريخ الأحداث: | Date Created: 20231223 Date Completed: 20240518 Latest Revision: 20240717 |
| رمز التحديث: | 20240718 |
| DOI: | 10.1016/j.gie.2023.12.022 |
| PMID: | 38141686 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1097-6779 |
|---|---|
| DOI: | 10.1016/j.gie.2023.12.022 |