تقرير
An unusual complication secondary to kanamycin use in a patient of multidrug-resistant pulmonary tuberculosis.
| العنوان: | An unusual complication secondary to kanamycin use in a patient of multidrug-resistant pulmonary tuberculosis. |
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| المؤلفون: | Mathews S; Junior Resident (Respiratory Medicine), Dr DY Patil Medical College, Hospital & Research Centre, Dr DY Patil Vidyapeeth, Pimpri, Pune, India., Dole S; Associate Professor (Respiratory Medicine), Dr DY Patil Medical College, Hospital & Research Centre, Dr DY Patil Vidyapeeth, Pimpri, Pune, India., Barthwal M; Professor & Head (Respiratory Medicine), Dr DY Patil Medical College, Hospital & Research Centre, Dr DY Patil Vidyapeeth, Pimpri, Pune, India., Sahasrabudhe T; Professor (Respiratory Medicine), Dr DY Patil Medical College, Hospital & Research Centre, Dr DY Patil Vidyapeeth, Pimpri, Pune, India. |
| المصدر: | Medical journal, Armed Forces India [Med J Armed Forces India] 2023 Dec; Vol. 79 (Suppl 1), pp. S280-S282. Date of Electronic Publication: 2021 Nov 28. |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: V. Parkash Country of Publication: India NLM ID: 7602492 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0377-1237 (Print) Linking ISSN: 03771237 NLM ISO Abbreviation: Med J Armed Forces India Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: New Delhi : V. Parkash |
| مستخلص: | Gitelman syndrome (GS) is a rare genetic renal disease characterized by hypomagnesemia, hypokalemia, hypocalciuria, and metabolic alkalosis. It usually presents in late childhood or early adulthood. A 30-year-old female diagnosed case of multidrug-resistant (MDR-TB) pulmonary tuberculosis 2 months ago presented to our outpatient department with intermittent painful spasms in all four limb muscles. Her treatment regimen consisted of kanamycin, levofloxacin, cycloserine, and ethionamide. On further evaluation, her investigations revealed hypokalemia, hypocalcemia, hypomagnesemia, metabolic alkalosis with normal serum creatinine level. She was initially treated with intravenous calcium and potassium. However, the electrolyte abnormalities and metabolic alkalosis persisted. All her lab parameters became normal after discontinuing kanamycin and electrolyte replacement for 4 weeks. She was discharged and advised to continue her antituberculosis treatment. There was no recurrence of symptoms on further follow up. Competing Interests: The authors have none to declare. (© 2021 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd.) |
| فهرسة مساهمة: | Keywords: Gitelman; Hypokalemia; Hypomagnesemia; Kanamycin; Tuberculosis |
| تواريخ الأحداث: | Date Created: 20231225 Latest Revision: 20231225 |
| رمز التحديث: | 20231225 |
| مُعرف محوري في PubMed: | PMC10746731 |
| DOI: | 10.1016/j.mjafi.2021.09.008 |
| PMID: | 38144646 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0377-1237 |
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| DOI: | 10.1016/j.mjafi.2021.09.008 |