دورية أكاديمية
أعرض في EDS

Doxycycline Prophylaxis for Skin and Soft Tissue Infections in Naval Special Warfare Trainees, United States 1 .

التفاصيل البيبلوغرافية
العنوان: Doxycycline Prophylaxis for Skin and Soft Tissue Infections in Naval Special Warfare Trainees, United States 1 .
المؤلفون: Spiro J, Wisniewski P, Schwartz J, Smith AG, Burger S, Tilley DH, Maves RC
المصدر: Emerging infectious diseases [Emerg Infect Dis] 2024 Jan; Vol. 30 (1), pp. 89-95.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-
مواضيع طبية MeSH: Doxycycline*/therapeutic use , Soft Tissue Infections*/epidemiology , Soft Tissue Infections*/prevention & control, United States/epidemiology ; Humans ; Retrospective Studies ; Skin ; Hospitalization
مستخلص: In 2015, several severe cases of skin and soft tissue infection (SSTI) among US Naval Special Warfare trainees prompted the introduction of doxycycline prophylaxis during the highest-risk portion of training, Hell Week. We performed a retrospective analysis of the effect of this intervention on SSTI incidence and resulting hospital admissions during 2013-2020. In total, 3,371 trainees underwent Hell Week training during the study period; 284 SSTIs were diagnosed overall, 29 of which led to hospitalization. After doxycycline prophylaxis was introduced, admission rates for SSTI decreased from 1.37 to 0.64 admissions/100 trainees (p = 0.036). Overall SSTI rates remained stable at 7.42 to 8.86 SSTIs/100 trainees (p = 0.185). Hospitalization rates per diagnosed SSTI decreased from 18.4% to 7.2% (p = 0.009). Average length of hospitalization decreased from 9.01 days to 4.33 days (p = 0.034). Doxycycline prophylaxis was associated with decreased frequency and severity of hospitalization for SSTIs among this population.
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فهرسة مساهمة: Keywords: SSTI; United States; bacteria; doxycycline; military; prophylaxis; saltwater exposure; skin and soft tissue infection
المشرفين على المادة: N12000U13O (Doxycycline)
تواريخ الأحداث: Date Created: 20231226 Date Completed: 20231227 Latest Revision: 20240102
رمز التحديث: 20240102
مُعرف محوري في PubMed: PMC10756378
DOI: 10.3201/eid3001.230890
PMID: 38146981
قاعدة البيانات: MEDLINE
الوصف
تدمد:1080-6059
DOI:10.3201/eid3001.230890