دورية أكاديمية

Resistance-only and concurrent exercise induce similar myofibrillar protein synthesis rates and associated molecular responses in moderately active men before and after training.

التفاصيل البيبلوغرافية
العنوان: Resistance-only and concurrent exercise induce similar myofibrillar protein synthesis rates and associated molecular responses in moderately active men before and after training.
المؤلفون: Lee MJ; Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia., Caruana NJ; Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia.; Department of Biochemistry and Pharmacology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia., Saner NJ; Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia., Kuang J; Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia., Stokes T; Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada., McLeod JC; Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada., Oikawa SY; Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada., Bishop DJ; Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia., Bartlett JD; Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia., Phillips SM; Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada.
المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Jan; Vol. 38 (1), pp. e23392.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE
أسماء مطبوعة: Publication: 2020- : [Bethesda, Md.] : Hoboken, NJ : Federation of American Societies for Experimental Biology ; Wiley
Original Publication: [Bethesda, Md.] : The Federation, [c1987-
مواضيع طبية MeSH: Body Composition* , Exercise*, Male ; Humans ; Exercise Tolerance ; Glycogen ; Muscles
مستخلص: Aerobic and resistance exercise (RE) induce distinct molecular responses. One hypothesis is that these responses are antagonistic and unfavorable for the anabolic response to RE when concurrent exercise is performed. This thesis may also depend on the participants' training status and concurrent exercise order. We measured free-living myofibrillar protein synthesis (MyoPS) rates and associated molecular responses to resistance-only and concurrent exercise (with different exercise orders), before and after training. Moderately active men completed one of three exercise interventions (matched for age, baseline strength, body composition, and aerobic capacity): resistance-only exercise (RE, n = 8), RE plus high-intensity interval exercise (RE+HIIE, n = 8), or HIIE+RE (n = 9). Participants trained 3 days/week for 10 weeks; concurrent sessions were separated by 3 h. On the first day of Weeks 1 and 10, muscle was sampled immediately before and after, and 3 h after each exercise mode and analyzed for molecular markers of MyoPS and muscle glycogen. Additional muscle, sampled pre- and post-training, was used to determine MyoPS using orally administered deuterium oxide (D 2 O). In both weeks, MyoPS rates were comparable between groups. Post-exercise changes in proteins reflective of protein synthesis were also similar between groups, though MuRF1 and MAFbx mRNA exhibited some exercise order-dependent responses. In Week 10, exercise-induced changes in MyoPS and some genes (PGC-1ɑ and MuRF1) were dampened from Week 1. Concurrent exercise (in either order) did not compromise the anabolic response to resistance-only exercise, before or after training. MyoPS rates and some molecular responses to exercise are diminished after training.
(© 2023 Federation of American Societies for Experimental Biology.)
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فهرسة مساهمة: Keywords: MPS; exercise order; glycogen; mRNA; signaling; training status
المشرفين على المادة: 9005-79-2 (Glycogen)
تواريخ الأحداث: Date Created: 20231228 Date Completed: 20231229 Latest Revision: 20240205
رمز التحديث: 20240206
DOI: 10.1096/fj.202302024R
PMID: 38153675
قاعدة البيانات: MEDLINE
الوصف
تدمد:1530-6860
DOI:10.1096/fj.202302024R