دورية أكاديمية

Clinical outcomes of different types of metallic stents in malignant distal duodenum stenosis: A retrospective study.

التفاصيل البيبلوغرافية
العنوان: Clinical outcomes of different types of metallic stents in malignant distal duodenum stenosis: A retrospective study.
المؤلفون: Su HJ; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Chen CC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan., Kuo YT; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; Division of Endoscopy, Department of Integrated Diagnostics and Therapeutics, National Taiwan University Hospital, Taipei, Taiwan., Han ML; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; Division of Endoscopy, Department of Integrated Diagnostics and Therapeutics, National Taiwan University Hospital, Taipei, Taiwan., Tsai MC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Liu KL; Department of Medical Imaging, National Taiwan University Cancer Center, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Wang HP; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address: wanghp@ntu.edu.tw.
المصدر: Journal of the Formosan Medical Association = Taiwan yi zhi [J Formos Med Assoc] 2024 Aug; Vol. 123 (8), pp. 854-859. Date of Electronic Publication: 2024 Jan 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Formosan Medical Association, Elsevier Country of Publication: Singapore NLM ID: 9214933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0929-6646 (Print) Linking ISSN: 09296646 NLM ISO Abbreviation: J Formos Med Assoc Subsets: MEDLINE
أسماء مطبوعة: Publication: 2003- : Singapore : Formosan Medical Association, Elsevier
Original Publication: Taipei, Taiwan : Formosan Medical Association, [1991-
مواضيع طبية MeSH: Self Expandable Metallic Stents* , Duodenal Obstruction*/etiology , Duodenal Obstruction*/surgery , Duodenal Obstruction*/therapy, Humans ; Female ; Male ; Aged ; Retrospective Studies ; Middle Aged ; Treatment Outcome ; Aged, 80 and over ; Stents/adverse effects ; Constriction, Pathologic ; Duodenum/surgery ; Taiwan
مستخلص: Background/purpose: Endoscopic stenting at malignant distal duodenum stenosis (MDDS) is challenging because of the duodenal C-loop configuration, the acute angle of the duodenojejunal junction, and the limited length of the endoscope. Few studies have investigated the clinical outcomes of stenting at the distal duodenum. Therefore, this study aimed to investigate the clinical outcomes of treating MDDS with different types of metallic stents.
Methods: From January 2012 to December 2020, fifty-six patients with MDDS who underwent duodenal stenting were enrolled for analysis. Thirty-five patients received uncovered self-expandable metallic stents (UC-SEMS), and twenty-one patients received partially covered self-expandable metallic stents (PC-SEMS). All patients were followed up till death or for 18 months. The clinical success rate, stent dysfunction rate, and stent patency were compared between the groups. Multivariate analysis was conducted to identify factors related to stent dysfunction.
Results: The clinical success rates were 85.7 % in both the UC-SEMS and PC-SEMS groups. Stent dysfunction rates (UC-SEMS: 34.3 %, PC-SEMS: 38.1 %, p = 0.773) and the average stent patency (UC-SEMS: 117.2 days, PC-SEMS: 100.0 days, p = 0.576) were not statistically different between the groups. Multivariate analysis disclosed the age ≥65 years was significantly related to stent dysfunction (odds ratio: 4.78, p = 0.031).
Conclusion: Both UC-SEMS and PC-SEMS are safe and effective treatment options for MDDS. However, stent dysfunction remains a significant issue to overcome, particularly in the elderly. Further research is needed to explore novel strategies that can improve the effectiveness of stent placement and reduce the risk of stent dysfunction.
Competing Interests: Declaration of competing interest All authors declare no conflicts of interest in this work.
(Copyright © 2024 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Endoscopy; Gastric outlet obstruction; Pancreatic cancer; Retrospective study
تواريخ الأحداث: Date Created: 20240103 Date Completed: 20240808 Latest Revision: 20240808
رمز التحديث: 20240809
DOI: 10.1016/j.jfma.2023.12.013
PMID: 38171957
قاعدة البيانات: MEDLINE
الوصف
تدمد:0929-6646
DOI:10.1016/j.jfma.2023.12.013