دورية أكاديمية
Pseudogenes act as a neutral reference for detecting selection in prokaryotic pangenomes.
العنوان: | Pseudogenes act as a neutral reference for detecting selection in prokaryotic pangenomes. |
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المؤلفون: | Douglas GM; Department of Microbiology and Immunology, McGill University, Montréal, Québec, Canada. gavin.douglas@mcgill.ca.; McGill Genome Centre, McGill University, Montréal, Québec, Canada. gavin.douglas@mcgill.ca., Shapiro BJ; Department of Microbiology and Immunology, McGill University, Montréal, Québec, Canada. jesse.shapiro@mcgill.ca.; McGill Genome Centre, McGill University, Montréal, Québec, Canada. jesse.shapiro@mcgill.ca.; McGill Centre for Microbiome Research, McGill University, Montréal, Québec, Canada. jesse.shapiro@mcgill.ca. |
المصدر: | Nature ecology & evolution [Nat Ecol Evol] 2024 Feb; Vol. 8 (2), pp. 304-314. Date of Electronic Publication: 2024 Jan 04. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Springer Nature Country of Publication: England NLM ID: 101698577 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2397-334X (Electronic) Linking ISSN: 2397334X NLM ISO Abbreviation: Nat Ecol Evol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: [London] : Springer Nature |
مواضيع طبية MeSH: | Pseudogenes* , Biological Evolution*, Genome ; Bacteria/genetics |
مستخلص: | A long-standing question is to what degree genetic drift and selection drive the divergence in rare accessory gene content between closely related bacteria. Rare genes, including singletons, make up a large proportion of pangenomes (all genes in a set of genomes), but it remains unclear how many such genes are adaptive, deleterious or neutral to their host genome. Estimates of species' effective population sizes (N (© 2024. The Author(s), under exclusive licence to Springer Nature Limited.) |
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Data and code for ‘Pseudogenes act as a neutral reference for detecting selection in prokaryotic pangenomes’. Zenodo https://doi.org/10.5281/zenodo.7942836 (2023). |
تواريخ الأحداث: | Date Created: 20240104 Date Completed: 20240214 Latest Revision: 20240722 |
رمز التحديث: | 20240723 |
DOI: | 10.1038/s41559-023-02268-6 |
PMID: | 38177690 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2397-334X |
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DOI: | 10.1038/s41559-023-02268-6 |