دورية أكاديمية
Copper-Catalyzed Synthesis of Masked (Hetero)Aryl Sulfinates.
| العنوان: | Copper-Catalyzed Synthesis of Masked (Hetero)Aryl Sulfinates. |
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| المؤلفون: | Merino MR; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, U.K., Cook XAF; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, U.K., Blakemore DC; Medicine Design, Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, United States., Moses IB; Pharmaceutical Sciences, Pfizer Inc., Discovery Park, Ramsgate Road, Kent CT13 9ND, U.K., Sach NW; Medicine Design, La Jolla Laboratories, Pfizer Inc., 10777 Science Center Drive, San Diego, California 92121, United States., Shavnya A; Medicine Design, Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, United States., Willis MC; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, U.K. |
| المصدر: | Organic letters [Org Lett] 2024 Apr 12; Vol. 26 (14), pp. 2817-2820. Date of Electronic Publication: 2024 Jan 08. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: PubMed not MEDLINE; MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, DC : American Chemical Society, c1999- |
| مستخلص: | Catalysis using substoichiometric copper facilitates the synthesis of masked (hetero)aryl sulfinates under mild, base-free conditions from aryl iodides and the commercial sulfonylation reagent sodium 1-methyl 3-sulfinopropanoate (SMOPS). The development of a tert -butyl ester variant of the SMOPS reagent allowed the use of aryl bromide substrates. The sulfones thus generated can be unmasked and functionalized in situ to form a variety of sulfonyl-containing functional groups. |
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| تواريخ الأحداث: | Date Created: 20240108 Latest Revision: 20240425 |
| رمز التحديث: | 20240425 |
| مُعرف محوري في PubMed: | PMC11020165 |
| DOI: | 10.1021/acs.orglett.3c03621 |
| PMID: | 38189248 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 1523-7052 |
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| DOI: | 10.1021/acs.orglett.3c03621 |