دورية أكاديمية
Ablation of persistent atrial fibrillation based on atrial electrogram duration map: methodology and clinical outcomes from the AEDUM pilot study.
| العنوان: | Ablation of persistent atrial fibrillation based on atrial electrogram duration map: methodology and clinical outcomes from the AEDUM pilot study. |
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| المؤلفون: | Rossi P; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy. rossi.ptr@gmail.com., Cauti FM; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy., Polselli M; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy., Magnocavallo M; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy., Niscola M; Abbott Medical, Via Paracelso 20, 20864, Agrate Brianza, Italy., Fanti V; Abbott Medical, Via Paracelso 20, 20864, Agrate Brianza, Italy., Limite LR; Unité d'Arythmologie, Hôpital Privé Les Franciscaines, Nîmes, France., Evangelista A; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy., Bellisario A; European Hospital, Via Portuense, 700, Rome, Italy., De Paolis R; European Hospital, Via Portuense, 700, Rome, Italy., Facchetti S; European Hospital, Via Portuense, 700, Rome, Italy., Quaglione R; Department of Internal, Anesthesiology and Cardiovascular Sciences, Policlinico Umberto I, Sapienza University of Rome, 00185, Rome, Italy., Piccirillo G; Department of Internal, Anesthesiology and Cardiovascular Sciences, Policlinico Umberto I, Sapienza University of Rome, 00185, Rome, Italy., Bianchi S; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy. |
| المصدر: | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing [J Interv Card Electrophysiol] 2024 Sep; Vol. 67 (6), pp. 1365-1376. Date of Electronic Publication: 2024 Jan 11. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: Netherlands NLM ID: 9708966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1572-8595 (Electronic) Linking ISSN: 1383875X NLM ISO Abbreviation: J Interv Card Electrophysiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Springer Original Publication: Norwell, MA : Kluwer Academic Publishers, c1997- |
| مواضيع طبية MeSH: | Atrial Fibrillation*/surgery , Atrial Fibrillation*/physiopathology , Catheter Ablation*/methods, Humans ; Male ; Female ; Pilot Projects ; Middle Aged ; Treatment Outcome ; Body Surface Potential Mapping/methods ; Electrocardiography, Ambulatory/methods |
| مستخلص: | Background: Catheter ablation of persistent atrial fibrillation (PsAF) represents a challenge for the electrophysiologist and there are still divergences regarding the best ablative approach to adopt. Create a new map of the duration of atrial bipolar electrograms (Atrial Electrogram DUration Map, AEDUM) to recognize a functional substrate during sinus rhythm and guide a patient-tailored ablative strategy for PsAF. Methods: Forty PsAF subjects were assigned in a 1:1 ratio to either for PVI alone (Group B Results: Electrogram (EGM) duration was higher in Group B than in Group A (49±16.2ms vs 34.2±3.8ms; p-value<0.001). In Group B the mean cumulative AEDUM area was 21.8±8.2cm 2 ; no difference between the two subgroups was observed (22.3±9.1cm 2 vs 21.2±7.2cm 2 ; p-value=0.45). The overall bipolar voltage recorded inside the AEDUM areas was lower than in the remaining atrial areas [median: 1.30mV (IQR: 0.71-2.38mV) vs 1.54mV (IQR: 0.79-2.97mV); p-value: <0.001)]. Low voltage areas (<0.5mV) were recorded in three (7.5%) patients in Group B. During the follow-up [median 511 days (376-845days)] patients who underwent PVI-only experienced more AF recurrence than those receiving a tailored approach (65% vs 35%; p-value= 0.04). Conclusions: All PsAF patients exhibited AEDUM areas. An ablation approach targeting these areas resulted in a more effective strategy compared with PVI only. (© 2024. The Author(s).) |
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| فهرسة مساهمة: | Keywords: AEDUM; Atrial fibrillation; Catheter ablation; Persistent atrial fibrillation; Pulmonary vein isolation |
| تواريخ الأحداث: | Date Created: 20240111 Date Completed: 20240906 Latest Revision: 20240910 |
| رمز التحديث: | 20240910 |
| مُعرف محوري في PubMed: | PMC11379763 |
| DOI: | 10.1007/s10840-023-01721-7 |
| PMID: | 38206451 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1572-8595 |
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| DOI: | 10.1007/s10840-023-01721-7 |