دورية أكاديمية
An abortion storm in a goat farm in the Northeast Region of Brazil was caused by the atypical Toxoplasma gondii genotype #13.
| العنوان: | An abortion storm in a goat farm in the Northeast Region of Brazil was caused by the atypical Toxoplasma gondii genotype #13. |
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| المؤلفون: | Vilela VLR; Department of Veterinary Medicine, Instituto Federal da Paraíba - IFPB, Sousa, Paraíba ZC 58800-970, Brazil., Feitosa TF; Department of Veterinary Medicine, Instituto Federal da Paraíba - IFPB, Sousa, Paraíba ZC 58800-970, Brazil., Simões SVD; Department of Veterinary Sciences, Universidade Federal da Paraíba - UFPB, Areia, Paraíba ZC 58397-000, Brazil., Mota RA; Department of Veterinary Medicine, Universidade Federal Rural de Pernambuco - UFRPE, Recife, Pernambuco ZC 52171-900, Brazil., Katzer F; Moredun Research Institute, Pentlands Science Park, Penicuik EH26 0PZ, Scotland, United Kingdom., Bartley PM; Moredun Research Institute, Pentlands Science Park, Penicuik EH26 0PZ, Scotland, United Kingdom. |
| المصدر: | Current research in parasitology & vector-borne diseases [Curr Res Parasitol Vector Borne Dis] 2023 Dec 21; Vol. 5, pp. 100157. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918226380706676 Publication Model: eCollection Cited Medium: Internet ISSN: 2667-114X (Electronic) Linking ISSN: 2667114X NLM ISO Abbreviation: Curr Res Parasitol Vector Borne Dis Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Amsterdam] : Elsevier B.V., [2021]- |
| مستخلص: | The objective of this study was to characterise a Toxoplasma gondii -induced abortion outbreak on a goat farm in the State of Paraíba, Northeast Region of Brazil. From a herd of 10 does, seven experienced abortions and one gave birth to twins (one stillborn and the other weak and underdeveloped). Serum samples from all of the does were analysed by indirect fluorescent antibody test (IFAT). Samples of colostrum and placenta from two does, along with lung, heart, brain and umbilical cord samples from four of the foetuses, were screened by nested ITS1 PCR specific for T. gondii . The positive samples were then analysed by multiplex nested PCR-RFLP. All ten does tested positive by IFAT for anti- T. gondii IgG (titrations ranging from 1:4096 to 1:65,536). The ITS1 PCR screening revealed T. gondii DNA in the placenta (2/2), colostrum (2/2), umbilical cord (2/4), lung (1/4), heart (1/4), and brain (1/4). Four samples produced complete RFLP genotyping results, identifying a single genotype, ToxoDB #13. In conclusion, we demonstrated a high rate of abortion caused by T. gondii in a goat herd, highlighting the pathogenicity of genotype #13, one of the most prevalent genotypes of T. gondii in Brazil. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Given their role as Co-Editor, Frank Katzer had no involvement in the peer review of this article and has no access to information regarding its peer review. Full responsibility for the editorial process for this article was delegated to Editor-in-Chief Aneta Kostadinova. (© 2023 The Author(s).) |
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| فهرسة مساهمة: | Keywords: IFAT; Outbreak; PCR-RFLP; Toxoplasmosis; Vertical transmission |
| تواريخ الأحداث: | Date Created: 20240115 Latest Revision: 20240116 |
| رمز التحديث: | 20240116 |
| مُعرف محوري في PubMed: | PMC10784673 |
| DOI: | 10.1016/j.crpvbd.2023.100157 |
| PMID: | 38223290 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2667-114X |
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| DOI: | 10.1016/j.crpvbd.2023.100157 |