دورية أكاديمية
The sodium-chloride difference: A marker of prognosis in patients with acute myocardial infarction.
| العنوان: | The sodium-chloride difference: A marker of prognosis in patients with acute myocardial infarction. |
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| المؤلفون: | Terlecki M; Department of Interdisciplinary Intensive Care, Jagiellonian University Medical College, Kraków, Poland., Kocowska-Trytko M; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Kurzyca A; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Pavlinec C; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Zając M; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland.; Student's Scientific Group in the 1st Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Rusinek J; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland.; Student's Scientific Group in the 1st Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Lis P; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Bednarski A; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Wojciechowska W; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Stolarz-Skrzypek K; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland., Rajzer M; First Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland. |
| المصدر: | European journal of clinical investigation [Eur J Clin Invest] 2024 May; Vol. 54 (5), pp. e14157. Date of Electronic Publication: 2024 Jan 16. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: England NLM ID: 0245331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2362 (Electronic) Linking ISSN: 00142972 NLM ISO Abbreviation: Eur J Clin Invest Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford : Wiley Original Publication: Berlin, New York, Springer-Verlag, on behalf of the European Society for Clinical Investigation. |
| مواضيع طبية MeSH: | Percutaneous Coronary Intervention* , Myocardial Infarction* , ST Elevation Myocardial Infarction*/complications, Male ; Humans ; Female ; Chlorides ; Sodium Chloride ; Prognosis ; Sodium ; Risk Factors |
| مستخلص: | Background: The difference between serum sodium and chloride ion concentrations (SCD) may be considered as a surrogate of a strong ion difference and may help to identify patients with a worse prognosis. We aimed to assess SCD as an early prognostic marker among patients with myocardial infarction. Methods: Data of 594 consecutive patients with acute myocardial infarction treated with PCI (44.9% STEMI patients; 70.7% males) was analysed for SCD in relation to their 30-day mortality. A restricted cubic spline regression model was used to study the relationship between mortality and SCD. Cox regression models were used to assess the association between SCD and the mortality risk. Results: Patients with Killip class ≥3 had lower SCD values in comparison to patients with Killip class ≤2: (32.0 [30.0-34.0] vs. 33.0 [31.0-36.0], p = .006). The overall 30-day mortality was 7.7% (n = 46). There was a significant difference in SCD values between survivors and non-survivors groups of patients (median (IQR): (33.0 [31.0-36.0] vs. 31.5 [28.0-34.0] (mmol/L), p = .002). The restricted cubic splines model confirmed a non-linear association between SCD and mortality. Patients with SCD <30 mmol/L (in comparison to SCD ≥30 mmol/L) had an increased mortality risk (unadjusted HR 2.92, 95% CI 1.59-5.36, p = .001; and an adjusted HR 2.30, 95% CI 1.02-5.19, p = .04). Conclusions: Low SCD on admission is associated with an increased risk of 30-day mortality in patients with acute myocardial infarction treated with PCI and may serve as a useful prognostic marker for these patients. (© 2024 Stichting European Society for Clinical Investigation Journal Foundation. Published by John Wiley & Sons Ltd.) |
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BMC Nephrol. 2021;22(1):343. |
| فهرسة مساهمة: | Keywords: Stewart's theory; myocardial infarction; prognostic marker; sodium–chloride difference; strong ion difference |
| المشرفين على المادة: | 0 (Chlorides) 451W47IQ8X (Sodium Chloride) 9NEZ333N27 (Sodium) |
| تواريخ الأحداث: | Date Created: 20240116 Date Completed: 20240417 Latest Revision: 20240417 |
| رمز التحديث: | 20240417 |
| DOI: | 10.1111/eci.14157 |
| PMID: | 38226439 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1365-2362 |
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| DOI: | 10.1111/eci.14157 |