دورية أكاديمية
أعرض في EDS

Dysmagnesemia as a predictor of developing diabetic levels of hemoglobin A1c.

التفاصيل البيبلوغرافية
العنوان: Dysmagnesemia as a predictor of developing diabetic levels of hemoglobin A1c.
المؤلفون: Ali SA; Department of Clinical Biochemistry, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark., Engell AE; Department of Clinical Biochemistry, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark., Lind BS; Department of Clinical Biochemistry, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark., Jørgensen HL; Department of Clinical Biochemistry, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
المصدر: Scandinavian journal of clinical and laboratory investigation [Scand J Clin Lab Invest] 2023 Dec; Vol. 83 (8), pp. 608-613. Date of Electronic Publication: 2024 Jan 24.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0404375 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1502-7686 (Electronic) Linking ISSN: 00365513 NLM ISO Abbreviation: Scand J Clin Lab Invest Subsets: MEDLINE
أسماء مطبوعة: Publication: London : Informa Healthcare
Original Publication: Oslo, Medisinsk Fysiologisk Forenings Forlag.
مواضيع طبية MeSH: Diabetes Mellitus* , Diabetes Mellitus, Type 2*, Humans ; Glycated Hemoglobin ; Blood Glucose ; Biomarkers ; Proportional Hazards Models
مستخلص: The aim of this study was to assess the possible association between P-Mg and subsequent high levels of HbA 1c. The study involves data from primary health care patients and data from patients treated in hospitals located in the capital region of Denmark. P-Mg and HbA 1c levels were analyzed from 121,575 patients in the period 2010-2022. Patients were categorized in a diabetic and non-diabetic group. Out of 121,575 patients, 8,532 were categorized as diabetic. A reverse J-shaped association between P-Mg and HbA 1c levels ≥ 48 mmol/mol was observed with nadir at P-Mg of 0.90 mmol/L. The unadjusted hazard ratio (HR) for having a first HbA 1c measurement ≥ 48 mmol/mol is 1.54 (95% Cl 1.50; 1.57) per 0.1 mmol/L decrease in P-Mg when P-Mg is lower than 0.90 mmol/L. After adjusting for age and gender, the HR remained significant at 1.45 (95% Cl 1.41; 1.48).For P-Mg levels above 0.90 mmol/L, the unadjusted HR per 0.1 mmol/L increase in P-Mg was 1.04 (95% Cl 1.02; 1.06). After adjusting for age and gender the HR remained significant at 1.06 (95% Cl 1.05; 1.08). In conclusion, this study found that patients with dysmagnesemia have a higher risk of developing diabetes even after adjusting for age and gender. Hyper- or hypomagnesemia in patients could be a biomarker for predicting the risk of developing diabetes.
فهرسة مساهمة: Keywords: HbA1c; hypomagnesemia; magnesium; type 2 diabetes
المشرفين على المادة: 0 (Glycated Hemoglobin)
0 (Blood Glucose)
0 (Biomarkers)
تواريخ الأحداث: Date Created: 20240116 Date Completed: 20240125 Latest Revision: 20240125
رمز التحديث: 20240125
DOI: 10.1080/00365513.2024.2303707
PMID: 38226930
قاعدة البيانات: MEDLINE
الوصف
تدمد:1502-7686
DOI:10.1080/00365513.2024.2303707