دورية أكاديمية
أعرض في EDS

A balancing act: drifting away from the reflexive use of "ab"normal saline.

التفاصيل البيبلوغرافية
العنوان: A balancing act: drifting away from the reflexive use of "ab"normal saline.
المؤلفون: Wang L; Department of Pediatrics, Division of Nephrology, Children's National Hospital, Washington, DC, USA. lwang4@childrensnational.org., Dixon C; Department of Pediatrics, Division of Critical Care Medicine, Children's National Hospital, Washington, DC, USA., Nhan J; Department of Pediatrics, Division of Nephrology, Children's National Hospital, Washington, DC, USA., Kakajiwala A; Department of Pediatrics, Division of Nephrology, Children's National Hospital, Washington, DC, USA.; Department of Pediatrics, Division of Critical Care Medicine, Children's National Hospital, Washington, DC, USA.
المصدر: Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2024 Aug; Vol. 39 (8), pp. 2325-2335. Date of Electronic Publication: 2024 Jan 18.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8708728 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-198X (Electronic) Linking ISSN: 0931041X NLM ISO Abbreviation: Pediatr Nephrol Subsets: MEDLINE
أسماء مطبوعة: Publication: Berlin : Springer International
Original Publication: Berlin : Springer International, c1987-
مواضيع طبية MeSH: Fluid Therapy*/methods , Fluid Therapy*/adverse effects , Hyponatremia*/prevention & control , Hyponatremia*/etiology , Saline Solution*/administration & dosage, Humans ; Child ; Acidosis/prevention & control ; Acidosis/chemically induced ; Acute Kidney Injury/prevention & control ; Acute Kidney Injury/etiology ; Acute Kidney Injury/chemically induced ; Hyperkalemia/etiology ; Hyperkalemia/prevention & control ; Hyperkalemia/chemically induced
مستخلص: Maintenance intravenous fluids are the most frequently ordered medications for hospitalized children. Since the American Association of Pediatrics published national guidelines, there has been an increased reflexive use of isotonic solutions, especially 0.9% saline, as a prophylaxis against hyponatremia. In this educational review, we discuss the potential deleterious effects of using 0.9% saline, including the development of hyperchloremia, metabolic acidosis, acute kidney injury, hyperkalemia, and a proinflammatory state. Balanced solutions with anion buffers cause relatively minimal harm when used in most children. While the literature supporting one fluid choice over the other is variable, we highlight the benefits of balanced solutions over saline and the importance of prescribing fluid therapy that is individualized for each patient.
(© 2024. The Author(s), under exclusive licence to International Pediatric Nephrology Association.)
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فهرسة مساهمة: Keywords: 0.9% saline; Balanced solutions; Hyperchloremia; Intravenous fluids
المشرفين على المادة: 0 (Saline Solution)
تواريخ الأحداث: Date Created: 20240117 Date Completed: 20240625 Latest Revision: 20240625
رمز التحديث: 20240625
DOI: 10.1007/s00467-023-06271-8
PMID: 38233719
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-198X
DOI:10.1007/s00467-023-06271-8