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Atypical disseminated histiocytic sarcoma in a 7-month-old dog.

التفاصيل البيبلوغرافية
العنوان: Atypical disseminated histiocytic sarcoma in a 7-month-old dog.
المؤلفون: Garcia-Torres M; Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Bellaterra, Spain., Muñoz BS; Departament de Sanitat i Anatomia Animals, Servei de Diagnòstic de Patologia Veterinària, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Spain., Segalés J; Departament de Sanitat i Anatomia Animals, Servei de Diagnòstic de Patologia Veterinària, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Centre de Recerca en Sanitat Animal (CReSA), Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Barcelona, Spain., Mallol C; Diagnostic Imaging Department, Anderson Moores Veterinary Specialists, Hampshire, UK., Sanz A; Departament de Medicina i Cirurgia Animals, Servei de Patologia Clínica, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Spain., López MC; Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Bellaterra, Spain., Roura X; Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Bellaterra, Spain.
المصدر: Veterinary clinical pathology [Vet Clin Pathol] 2024 Mar; Vol. 53 (1), pp. 122-130. Date of Electronic Publication: 2024 Jan 19.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: American Society for Veterinary Clinical Pathology Country of Publication: United States NLM ID: 9880575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-165X (Electronic) Linking ISSN: 02756382 NLM ISO Abbreviation: Vet Clin Pathol Subsets: MEDLINE
أسماء مطبوعة: Publication: 1998- : Baton Rouge, LA : American Society for Veterinary Clinical Pathology
Original Publication: 1977-<1989> : Columbia, MO : Veterinary Practice Pub. Co.
مواضيع طبية MeSH: Histiocytic Sarcoma*/pathology , Histiocytic Sarcoma*/veterinary , Sarcoma*/pathology , Sarcoma*/veterinary , Dog Diseases*/diagnosis, Dogs ; Animals ; Female ; Biopsy, Fine-Needle/veterinary ; Histiocytes/pathology
مستخلص: A 7-month-old intact female bearded collie dog was admitted after a 2-week history of progressive cough, inappetence, and lethargy, with no response to previous treatment with doxycycline and steroids. Mild attenuation of lung sounds in the right middle hemithorax was the only abnormality detected on physical examination. Abdominal ultrasound and thoracic radiographs were performed and revealed multifocally distributed nodules and masses, well-circumscribed and of variable size in the kidneys and pulmonary parenchyma. Ultrasound-guided fine needle aspirates of the renal and pulmonary masses were taken. A cytologic evaluation of these lesions pointed towards a malignant mesenchymal neoplasia. Euthanasia was elected due to the poor prognosis and rapid progression. The post-mortem histopathology, a positive result to IBA1 immunoperoxidase staining, and a lack of detection of infectious agents, and negative E-cadherin immunostaining enabled the final diagnosis of a disseminated histiocytic sarcoma. We report an atypical form, both in breed and age, of canine disseminated histiocytic sarcoma. While all breeds can be affected, there is a clear predisposition in some, and no cases have been previously described in bearded collies. Moreover, to the authors' knowledge, this is the youngest dog with this histiocytic disorder described to date. Disseminated histiocytic sarcoma should be considered as a differential diagnosis of multinodular tumors in dogs, regardless of the anatomic location and age of the dogs, even in puppies.
(© 2024 American Society for Veterinary Clinical Pathology.)
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فهرسة مساهمة: Keywords: canine; dendritic cells; kidney; lung; mesenchymal neoplasia; puppy
تواريخ الأحداث: Date Created: 20240119 Date Completed: 20240314 Latest Revision: 20240314
رمز التحديث: 20240314
DOI: 10.1111/vcp.13328
PMID: 38242688
قاعدة البيانات: MEDLINE
الوصف
تدمد:1939-165X
DOI:10.1111/vcp.13328