دورية أكاديمية

Malignant pleural effusion: current understanding and therapeutic approach.

التفاصيل البيبلوغرافية
العنوان: Malignant pleural effusion: current understanding and therapeutic approach.
المؤلفون: Gonnelli F; Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, Ancona Via Conca 71, Ancona, 60126, Italy., Hassan W; Department of Respiratory Medicine, Sheffield Teaching Hospitals, University of Sheffield, Sheffield, UK., Bonifazi M; Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, Ancona Via Conca 71, Ancona, 60126, Italy., Pinelli V; Pulmonology Unit, San Bartolomeo Hospital, Sarzana, Italy., Bedawi EO; Department of Respiratory Medicine, Sheffield Teaching Hospitals, University of Sheffield, Sheffield, UK., Porcel JM; Research Group of Cancer Biomarkers, Lleida Institute for Biomedical Research Dr. Pifarré Foundation (IRBLleida), Lleida, Spain.; Pleural Medicine and Clinical Ultrasound Unit, Department of Internal Medicine, Arnau de Vilanova, University Hospital, Lleida, Spain., Rahman NM; Oxford Pleural Unit, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.; Oxford NIHR Biomedical Research Unit, Oxford, UK.; Chinese Academy of Medicine Oxford Institute, Oxford, UK., Mei F; Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, Ancona Via Conca 71, Ancona, 60126, Italy. federico.mei@ospedaliriuniti.marche.it.
المصدر: Respiratory research [Respir Res] 2024 Jan 19; Vol. 25 (1), pp. 47. Date of Electronic Publication: 2024 Jan 19.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE
أسماء مطبوعة: Publication: 2001- : London : BioMed Central Ltd.
Original Publication: London : Current Science Ltd., c2000-
مواضيع طبية MeSH: Pleural Effusion, Malignant*/diagnosis , Pleural Effusion, Malignant*/therapy, Humans ; Pleurodesis ; Talc ; Catheters, Indwelling ; Drainage/methods
مستخلص: Malignant pleural effusion (MPE) is a common complication of thoracic and extrathoracic malignancies and is associated with high mortality and elevated costs to healthcare systems. Over the last decades the understanding of pathophysiology mechanisms, diagnostic techniques and optimal treatment intervention in MPE have been greatly advanced by recent high-quality research, leading to an ever less invasive diagnostic approach and more personalized management. Despite a number of management options, including talc pleurodesis, indwelling pleural catheters and combinations of the two, treatment for MPE remains symptom directed and centered around drainage strategy. In the next future, because of a better understanding of underlying tumor biology together with more sensitive molecular diagnostic techniques, it is likely that combined diagnostic and therapeutic procedures allowing near total outpatient management of MPE will become popular. This article provides a review of the current advances, new discoveries and future directions in the pathophysiology, diagnosis and management of MPE.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Chest drain; Indwelling pleural catheter (IPC); Malignant pleural effusion (MPE); Oncology; Pleural; Pleurodesis; Thoracoscopy
المشرفين على المادة: 14807-96-6 (Talc)
تواريخ الأحداث: Date Created: 20240119 Date Completed: 20240122 Latest Revision: 20240122
رمز التحديث: 20240122
مُعرف محوري في PubMed: PMC10797757
DOI: 10.1186/s12931-024-02684-7
PMID: 38243259
قاعدة البيانات: MEDLINE
الوصف
تدمد:1465-993X
DOI:10.1186/s12931-024-02684-7