دورية أكاديمية
Uterine cancer among Asian Americans - Disparities & clinical characteristics.
| العنوان: | Uterine cancer among Asian Americans - Disparities & clinical characteristics. |
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| المؤلفون: | Johnson CR; California Pacific Medical Center Research Institute, 1100 Van Ness, San Francisco, CA 94109, USA. Electronic address: crjohnson19@gwu.edu., Liao CI; Pingtung Veterans General Hospital, Department of Obstetrics and Gynecology, Pingtung, Taiwan., Tian C; Gynecologic Cancer Center of Excellence Program, Henry M Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Richardson MT; University of California, Los Angeles, Department of Obstetrics and Gynecology, 757 Westwood Blvd, Los Angeles, CA, USA., Duong K; Western University of Health Sciences, College of Osteopathic Medicine, 309 E 2nd St, Pomona, CA 91766, USA., Tran N; California Pacific Medical Center Research Institute, 1100 Van Ness, San Francisco, CA 94109, USA., Winkler SS; Brooke Army Medical Center, Department of Obstetrics and Gynecology, 3551 Roger Brooke Dr., Fort Sam Houston, TX, United States of America., Kapp DS; Stanford University School of Medicine, Department of Radiation Oncology, 875 Blake Wilbur Dr, Stanford, CA 94304, USA., Darcy K; Gynecologic Cancer Center of Excellence Program, Henry M Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Chan JK; California Pacific Medical Center Research Institute, 1100 Van Ness, San Francisco, CA 94109, USA. |
| المصدر: | Gynecologic oncology [Gynecol Oncol] 2024 Mar; Vol. 182, pp. 24-31. Date of Electronic Publication: 2024 Jan 20. |
| نوع المنشور: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, Academic Press. |
| مواضيع طبية MeSH: | Asian* , South Asian People* , Uterine Neoplasms*/epidemiology, Female ; Humans ; Asian People ; Incidence ; United States/epidemiology ; White ; Ethnicity |
| مستخلص: | Objective: To evaluate the patterns and trends of uterine cancer among Asian subgroups living in the U.S. Methods: Data were obtained from United States Cancer Statistics (2001-2017), National Cancer Database (2004-2015), and World Population Review (2023). SEER*Stat version 8.3.9.2, Joinpoint regression program 4.9.0.0, and SAS v 9.4 were employed for statistical analysis. Results: Based on data from 778,891 women in the United States Cancer Statistics database, Asians had a 3.4-fold higher rate of incident uterine cancer compared to White populations (2.14% vs. 0.63%; p < 0.001). Using the National Cancer Database, 7,641 Asian women from six subgroups were analyzed: Filipino, Korean, Indian/Pakistani, Vietnamese, Chinese, and Japanese. Indian and Pakistani women had the greatest increase in the proportion of cancer diagnoses (5.0% to 14.4%; p = 0.0003). Additionally, Indian and Pakistani patients had higher comorbidity scores while Koreans had the lowest (22.7% vs. 10.7%, p < 0.0001). Regarding stage of disease, 25.3% of Filipinos presented with advanced stage disease compared to 19.2% of Indians and Pakistanis (p = 0.0001). Furthermore, Filipinos had the highest proportion of non-endometrioid cancers at 18.4% compared to other subgroups (p = 0.0003). Using the World Population Review, female obesity was highest in Pakistan (8.6%) and the Philippines (7.5%) and lowest in Vietnam (2.6%). Conclusion: Uterine cancer incidence increased at higher rates among Asians compared to White populations. Specifically, Indian and Pakistani uterine cancer patients were more likely to have higher comorbidity rates and Filipino patients had more advanced stage cancer with non-endometrioid histologies than other Asian subgroups. Further research is warranted to better understand these trends. Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Dr. John K Chan has consulted for AstraZeneca, GlaxoSmithKline, Genmab/Seagen, Immunogen, Karyopharm, Merck, Mersana, Myriad, and Roche. Dr. Chan has received payment/honoraria for lectures and traveling support from AstraZeneca, Eisai, Genmab/Seagen, GlaxoSmithKline, Immunogen, Merck, and Myriad. He has also participated on an advisory board for AstraZeneca, GlaxoSmithKline, and Myriad. The other authors have no conflicts of interests to declare. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Asian Americans; Disparities; Uterine cancer |
| تواريخ الأحداث: | Date Created: 20240121 Date Completed: 20240325 Latest Revision: 20240812 |
| رمز التحديث: | 20240813 |
| DOI: | 10.1016/j.ygyno.2023.12.023 |
| PMID: | 38246043 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1095-6859 |
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| DOI: | 10.1016/j.ygyno.2023.12.023 |