دورية أكاديمية
أعرض في EDS

Customizable Three-Dimensional Printed Earring Tap for Treating Affections Caused by Aesthetic Perforations.

التفاصيل البيبلوغرافية
العنوان: Customizable Three-Dimensional Printed Earring Tap for Treating Affections Caused by Aesthetic Perforations.
المؤلفون: Pinho LAG; Laboratory of Food, Drugs, and Cosmetics (LTMAC), University of Brasilia, Brasilia 70910-900, DF, Brazil., Lima AL; Laboratory of Food, Drugs, and Cosmetics (LTMAC), University of Brasilia, Brasilia 70910-900, DF, Brazil., Chen Y; Laboratory for Drug Delivery & Translational Medicine, School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong 226001, China., Sa-Barreto LL; Laboratory of Food, Drugs, and Cosmetics (LTMAC), University of Brasilia, Brasilia 70910-900, DF, Brazil., Marreto RN; Laboratory of Nanosystems and Drug Delivery Devices (NanoSYS), School of Pharmacy, Federal University of Goias, Goiania 74605-170, GO, Brazil., Gelfuso GM; Laboratory of Food, Drugs, and Cosmetics (LTMAC), University of Brasilia, Brasilia 70910-900, DF, Brazil., Gratieri T; Laboratory of Food, Drugs, and Cosmetics (LTMAC), University of Brasilia, Brasilia 70910-900, DF, Brazil., Cunha-Filho M; Laboratory of Food, Drugs, and Cosmetics (LTMAC), University of Brasilia, Brasilia 70910-900, DF, Brazil.
المصدر: Pharmaceutics [Pharmaceutics] 2024 Jan 05; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 05.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI
مستخلص: This work aimed to develop a three-dimensional (3D) wearable drug-loaded earring tap to treat affections caused by aesthetic perforations. The initial phase involved a combination of polymers to prepare filaments for fused deposition modeling (FDM) 3D printing using a centroid mixture design. Optimized filament compositions were used in the second phase to produce 3D printed earring taps containing the anti-inflammatory naringenin. Next, samples were assessed via physicochemical assays followed by in vitro skin permeation studies with porcine ear skin. Two filament compositions were selected for the study's second phase: one to accelerate drug release and another with slow drug dissolution. Both filaments demonstrated chemical compatibility and amorphous behavior. The use of the polymer blend to enhance printability has been confirmed by rheological analysis. The 3D devices facilitated naringenin skin penetration, improving drug recovery from the skin's most superficial layer (3D device A) or inner layers (3D device B). Furthermore, the devices significantly decreased transdermal drug delivery compared to the control containing the free drug. Thus, the resulting systems are promising for producing 3D printed earring taps with topical drug delivery and reinforcing the feasibility of patient-centered drug administration through wearable devices.
References: Int J Pharm. 2021 May 1;600:120442. (PMID: 33675925)
J Pharm Sci. 2018 Jan;107(1):286-296. (PMID: 28847477)
Int J Pharm. 2021 Jul 15;604:120755. (PMID: 34052338)
Int J Biol Macromol. 2020 Dec 1;164:717-725. (PMID: 32698069)
Pharmaceutics. 2019 Apr 04;11(4):. (PMID: 30987304)
Int J Pharm. 2021 Aug 10;605:120794. (PMID: 34119578)
Eur J Orthop Surg Traumatol. 2019 Jul;29(5):967-973. (PMID: 30864016)
Pharmaceutics. 2023 Jan 24;15(2):. (PMID: 36839717)
Eur J Pharm Sci. 2015 Jul 30;75:10-24. (PMID: 25746955)
J Pharm Anal. 2022 Jun;12(3):424-435. (PMID: 35811629)
Int J Pharm. 2021 Apr 15;599:120410. (PMID: 33639229)
J Pharm Biomed Anal. 2020 Jan 30;178:112937. (PMID: 31679845)
J Control Release. 2019 May 10;301:140-145. (PMID: 30876952)
Pediatr Rev. 2019 Jan;40(1):49-50. (PMID: 30600281)
Eur J Pharm Sci. 2021 Mar 1;158:105655. (PMID: 33253883)
Pharmaceutics. 2021 Nov 17;13(11):. (PMID: 34834360)
Pharm Res. 2018 May 31;35(8):151. (PMID: 29855818)
Expert Rev Med Devices. 2017 Sep;14(9):685-696. (PMID: 28774216)
J Control Release. 2016 Jul 28;234:41-8. (PMID: 27189134)
Adv Drug Deliv Rev. 2021 Jul;174:294-316. (PMID: 33895212)
Int J Pharm. 2022 Nov 5;627:122231. (PMID: 36167188)
Adv Drug Deliv Rev. 2021 Jul;174:553-575. (PMID: 33965461)
Int J Pharm. 2017 Jul 15;527(1-2):21-30. (PMID: 28502898)
Sci Rep. 2021 Jan 12;11(1):581. (PMID: 33436705)
Int J Pharm. 2018 Sep 5;548(1):586-596. (PMID: 30033380)
Int J Pharm. 2021 May 1;600:120501. (PMID: 33746011)
Eur J Pharm Sci. 2019 Mar 1;129:110-123. (PMID: 30610954)
Int J Environ Res Public Health. 2023 May 08;20(9):. (PMID: 37174261)
Int J Pharm. 2021 Mar 15;597:120301. (PMID: 33540018)
Pharmaceutics. 2019 Dec 03;11(12):. (PMID: 31816898)
Pharmaceutics. 2022 Mar 23;14(4):. (PMID: 35456524)
معلومات مُعتمدة: 00193-00000735/2021-10 Foundation for Research Support of the Federal District
فهرسة مساهمة: Keywords: FDM printing; aesthetic perforation; drug topical delivery; pharmaceutical jewelry; wearable devices
تواريخ الأحداث: Date Created: 20240123 Latest Revision: 20240129
رمز التحديث: 20240129
مُعرف محوري في PubMed: PMC10818553
DOI: 10.3390/pharmaceutics16010077
PMID: 38258088
قاعدة البيانات: MEDLINE
الوصف
تدمد:1999-4923
DOI:10.3390/pharmaceutics16010077