دورية أكاديمية
Impairment in work and activities of daily life in patients with psoriasis: results of the prospective BioCAPTURE registry.
| العنوان: | Impairment in work and activities of daily life in patients with psoriasis: results of the prospective BioCAPTURE registry. |
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| المؤلفون: | van Hal TW; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, the Netherlands.; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., van den Reek JMPA; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Dermatology, Radboud University Medical Center, Nijmegen, the Netherlands., Wenink MH; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, the Netherlands., Otero ME; Department of Dermatology, Radboud University Medical Center, Nijmegen, the Netherlands., Ossenkoppele PM; Department of Dermatology, ZiekenhuisGroep Twente, Almelo/Hengelo, the Netherlands., Njoo MD; Department of Dermatology, ZiekenhuisGroep Twente, Almelo/Hengelo, the Netherlands., Oostveen A; Department of Dermatology, Gelre Ziekenhuizen, Apeldoorn, the Netherlands., Peters B; Department of Dermatology, Ziekenhuis Rijnstate, Arnhem, the Netherlands., Tjioe M; Department of Dermatology/DermaTeam, Bravis Ziekenhuis, Bergen op Zoom, the Netherlands., Kop EN; Department of Dermatology, Bernhoven Ziekenhuis, Uden, the Netherlands., Körver JEM; Department of Dermatology, Amphia Ziekenhuis, Breda, the Netherlands., Dodemont SRP; Department of Dermatology, Catharina Ziekenhuis, Eindhoven, the Netherlands., Kleinpenning MM; Department of Dermatology, Canisius-Wilhelmina Ziekenhuis, Nijmegen, the Netherlands., Berends MAM; Department of Dermatology, Slingeland Ziekenhuis, Doetinchem, the Netherlands., Veldkamp WR; Department of Dermatology, Ziekenhuis Gelderse Vallei, Ede, the Netherlands., van Doorn MBA; Department of Dermatology, ErasmusMC, Rotterdam, the Netherlands., Mommers JM; Department of Dermatology, St. Anna Ziekenhuis, Geldrop, the Netherlands., Lindhout RJ; Department of Dermatology, Jeroen Bosch Ziekenhuis, 's Hertogenbosch, the Netherlands., Kuijpers ALA; Department of Dermatology, Maxima Medisch Centrum, Eindhoven, the Netherlands., van Lümig PP; Department of Dermatology, Maastricht UMC+, Maastricht, the Netherlands., de Jonge CEJ; Department of Dermatology, UMC Utrecht, Utrecht, the Netherlands., Tupker RA; Department of Dermatology, Sint Antoniusziekenhuis, Nieuwegein, the Netherlands., Hendricksen J; Department of Dermatology, Streekziekenhuis Koningin Beatrix, Winterswijk, the Netherlands., Keijsers RR; Department of Dermatology, Zuyderland Medisch Centrum, Sittard-Geleen, the Netherlands., van den Hoogen FHJ; Faculty of Medical Sciences, Radboud University, Nijmegen, the Netherlands., Vriezekolk JE; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, the Netherlands.; Department of Research & Innovation, Sint Maartenskliniek, Nijmegen, the Netherlands., de Jong EMGJ; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Dermatology, ZiekenhuisGroep Twente, Almelo/Hengelo, the Netherlands. |
| المصدر: | The Journal of dermatological treatment [J Dermatolog Treat] 2024 Dec; Vol. 35 (1), pp. 2304025. Date of Electronic Publication: 2024 Jan 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: Houndmills, Basingstoke, Hampshire, UK : M. Dunitz and Macmillan Press, [c1989]- |
| مواضيع طبية MeSH: | Activities of Daily Living* , Psoriasis*, Humans ; Prospective Studies ; Cognition ; Registries |
| مستخلص: | Background: Little is known about the extent of impairments in work and activities of daily life (ADL) in patients with psoriasis, and the influence of contextual factors such as disease-related characteristics and treatment. Therefore, this study aimed to assess these impairments in patients with psoriasis who started using biologicals/small molecule inhibitors. Methods: Using data from the prospective BioCAPTURE registry, we collected patient, disease, and treatment parameters, as well as work/ADL impairments at baseline, 6 and 12 months. Changes in impairment parameters and correlations between impairment and patient/disease characteristics were assessed using generalized estimating equations. Results: We included 194 patients in our analysis. After biological initiation, disease activity decreased significantly (PASI 11.2 at baseline versus 3.9 at 12 months, p < 0.001). Work-for-pay in this cohort was lower than in the Dutch general population (53% versus 67%, p = 0.01). In patients who had work-for-pay, presenteeism improved over time (5% at baseline versus 0% at 12 months, p = 0.04). Up to half of the patients reported impairments in ADL, which did not change over time. Associations between impairments and contextual factors varied, but all impairments were associated with worse mental/physical general functioning. Conclusion: Patients with psoriasis using biologicals are less likely to have work-for-pay. Treatment improves the work productivity of employed patients, but we were unable to detect changes in ADL performance. |
| فهرسة مساهمة: | Keywords: Psoriasis; activities of daily living; work |
| تواريخ الأحداث: | Date Created: 20240124 Date Completed: 20240125 Latest Revision: 20240125 |
| رمز التحديث: | 20240125 |
| DOI: | 10.1080/09546634.2024.2304025 |
| PMID: | 38263716 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1471-1753 |
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| DOI: | 10.1080/09546634.2024.2304025 |