دورية أكاديمية

Diffusion-weighted imaging does not seem to be a predictor of consistency in pituitary adenomas.

التفاصيل البيبلوغرافية
العنوان: Diffusion-weighted imaging does not seem to be a predictor of consistency in pituitary adenomas.
المؤلفون: Barbosa MA; Radiology Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil. moniqab@hotmail.com.; MRI Unit, Clínica de Diagnóstico por Imagem, DASA, Rio de Janeiro, Brazil. moniqab@hotmail.com.; Serviço de Radiologia, Instituto Estadual do Cérebro Paulo Niemeyer, Rua do Rezende, 156, Centro, Rio de Janeiro, 20231-092, Brazil. moniqab@hotmail.com., Pereira EGR; Neurosurgery Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil., da Mata Pereira PJ; Neurosurgery Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil., Guasti AA; Neurosurgery Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil., Andreiuolo F; Neuropathology and Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil., Chimelli L; Neuropathology and Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil., Kasuki L; Neuroendocrinology Research Center/Endocrinology Division, Medical School and Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil.; Neuroendocrine Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil.; Endocrinology Division, Hospital Federal de Bonsucesso, Rio de Janeiro, Brazil., Ventura N; Radiology Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil.; Neuroradiology Division, Medical School and Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil.; Neuroradiology Unit, Samaritano Hospital, Grupo Fleury, Rio de Janeiro, Brazil., Gadelha MR; Neuropathology and Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil.; Neuroendocrinology Research Center/Endocrinology Division, Medical School and Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil.; Neuroendocrine Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil.
المصدر: Pituitary [Pituitary] 2024 Apr; Vol. 27 (2), pp. 187-196. Date of Electronic Publication: 2024 Jan 25.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Kluwer Academic Publishers Country of Publication: United States NLM ID: 9814578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7403 (Electronic) Linking ISSN: 1386341X NLM ISO Abbreviation: Pituitary Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Norwell, MA : Kluwer Academic Publishers, 1998-
مواضيع طبية MeSH: Pituitary Neoplasms*/diagnostic imaging , Pituitary Neoplasms*/surgery , Pituitary Neoplasms*/pathology , Adenoma*/diagnostic imaging , Adenoma*/surgery , Adenoma*/pathology, Humans ; Diffusion Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging/methods ; Retrospective Studies
مستخلص: Purpose: To prospectively evaluate the usefulness of T1-weighted imaging (T1WI) and diffusion-weighted imaging (DWI) sequences in predicting the consistency of macroadenomas. In addition, to determine their values ​​as prognostic factors of surgical outcomes.
Methods: Patients with pituitary macroadenoma and surgical indication were included. All patients underwent pre-surgical magnetic resonance imaging (MRI) that included the sequences T1WI before and after contrast administration and DWI with the apparent diffusion coefficient (ADC) map. Post-surgical MRI was performed at least 3 months after surgery. The consistency of the macroadenomas was evaluated at surgery, and they were grouped into soft and intermediate/hard adenomas. Mean ADC values, signal on T1WI and the ratio of tumor ADC values ​​to pons (ADC R ) were compared with tumor consistency and grade of surgical resection.
Results: A total of 80 patients were included. A softened consistency was found at surgery in 53 patients and hardened in 27 patients. The median ADC in the soft consistency group was 0.532 × 10 -3 mm 2 /sec (0.306 - 1.096 × 10 -3 mm 2 /sec), and in the intermediate/hard consistency group was 0.509 × 10 -3 mm 2 /sec (0.308 - 0.818 × 10 -3 mm 2 /sec). There was no significant difference between the median values ​​of ADC, ADC R and signal on T1W between the soft and hard tumor groups, or between patients with and without tumor residue.
Conclusion: Our results did not show usefulness of the DWI and T1WI for assessing the consistency of pituitary macroadenomas, nor as a predictor of the degree of surgical resection.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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فهرسة مساهمة: Keywords: Consistency; Diffusion-weighted imaging; Magnetic resonance imaging; Pituitary adenoma
تواريخ الأحداث: Date Created: 20240125 Date Completed: 20240415 Latest Revision: 20240415
رمز التحديث: 20240415
DOI: 10.1007/s11102-023-01377-6
PMID: 38273189
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-7403
DOI:10.1007/s11102-023-01377-6