دورية أكاديمية
Application of cantharidin, retinoic acid cream and salicylic acidy in multiple palmoplantar warts.
| العنوان: | Application of cantharidin, retinoic acid cream and salicylic acidy in multiple palmoplantar warts. |
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| المؤلفون: | Zhang L; Department of Dermatology, Wuxi NO 2 People's Hospital, Central Hospital Affiliated to Jiang nan University, Wuxi, Jiangsu, China., Cheng S; Department of Dermatology, Xishan People's Hospital of Wuxi City, Wuxi Branch of Zhongda Hospital Southeast University, Wuxi, Jiangsu, China., Chen C; Department of Dermatology, Xishan People's Hospital of Wuxi City, Wuxi Branch of Zhongda Hospital Southeast University, Wuxi, Jiangsu, China., Fang L; Department of Dermatology, Xishan People's Hospital of Wuxi City, Wuxi Branch of Zhongda Hospital Southeast University, Wuxi, Jiangsu, China., Cui C; Department of Dermatology, Xishan People's Hospital of Wuxi City, Wuxi Branch of Zhongda Hospital Southeast University, Wuxi, Jiangsu, China. |
| المصدر: | Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2024 Feb; Vol. 30 (2), pp. e13586. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Country of Publication: England NLM ID: 9504453 Publication Model: Print Cited Medium: Internet ISSN: 1600-0846 (Electronic) Linking ISSN: 0909752X NLM ISO Abbreviation: Skin Res Technol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <1998-> : Oxford : Blackwell Original Publication: Copenhagen, Denmark ; Cambridge, MA : Munksgaard, c1995- |
| مواضيع طبية MeSH: | Salicylic Acid*/adverse effects , Warts*/drug therapy, Humans ; Cantharidin/adverse effects ; Tretinoin/therapeutic use ; Treatment Outcome |
| مستخلص: | Objective: Multiple palmoplantar warts, caused by human papillomavirus (HPV) infection, were investigated for clinical efficacy using cantharidin, retinoic acid cream, and salicylic acid cream. Methods: A total of 110 patients with multiple palmoplantar warts were enrolled. The experimental group (54 cases) received a 1:1:1 combination (CRS) of 0.25% cantharidin, 0.1% retinoic acid cream, and 5% salicylic acid, applied with pressurized encapsulation for 8 h every night, three times per week. The control group (56 cases) underwent conventional liquid nitrogen freezing. Monthly follow-ups assessed cure rate, effective rate, dermatological life quality index (DLQI), visual analog scale (VAS), and cost, with evaluations conducted after 3 months. Results: The treatment group exhibited a cure rate of 85.19% and a total effective rate of 96.30%, surpassing the control group with rates of 39.29% and 51.79%, respectively (p < 0.05). The treatment group's DLQI score (1.84 ± 1.06) was significantly lower than the control group's score (6.04 ± 1.78) (p = 0.0005). Additionally, the treatment group's VAS score (1.84 ± 1.06) was notably lower than the control group's score (8.56 ± 1.07) (p < 0.0001). The treatment group's total cost (43.20 ± 2.85) was markedly lower than the control group's cost (206.38 ± 90.81), with a statistically significant difference (p < 0.0001). Conclusion: The combination of cantharidin, retinoic acid cream, and salicylic acid with local encapsulation is a safe, effective, economical, and convenient treatment method for multiple palmoplantar warts, exhibiting few side effects and showing promise. (© 2024 The Authors. Skin Research and Technology published by John Wiley & Sons Ltd.) |
| References: | Clin Med Res. 2006 Dec;4(4):273-93. (PMID: 17210977) Clin Dermatol. 2021 Jul-Aug;39(4):688-694. (PMID: 34809773) J Evid Based Med. 2022 Sep;15(3):284-301. (PMID: 36117295) Dermatol Ther. 2016 Jul;29(4):269-73. (PMID: 27072919) Dermatol Ther. 2022 Sep;35(9):e15726. (PMID: 35864578) Infect Drug Resist. 2022 Jul 27;15:4059-4063. (PMID: 35924013) Gac Med Mex. 2015 Jan-Feb;151(1):14-9. (PMID: 25739479) Skin Res Technol. 2024 Feb;30(2):e13586. (PMID: 38279540) J Dermatolog Treat. 2022 Feb;33(1):23-40. (PMID: 32116076) |
| معلومات مُعتمدة: | Q202166 Scientific Research Program of Wuxi Health Commission; HB2023115 Program for Young and Middle-aged Individuals of Wuxi Health Committee; 82302562 National Natural Science Foundation of China |
| فهرسة مساهمة: | Keywords: cantharidin; multiple palmoplantar; retinoic acid cream; salicylic acid; verruca |
| المشرفين على المادة: | O414PZ4LPZ (Salicylic Acid) IGL471WQ8P (Cantharidin) 5688UTC01R (Tretinoin) |
| تواريخ الأحداث: | Date Created: 20240127 Date Completed: 20240129 Latest Revision: 20240129 |
| رمز التحديث: | 20240129 |
| مُعرف محوري في PubMed: | PMC10818119 |
| DOI: | 10.1111/srt.13586 |
| PMID: | 38279540 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1600-0846 |
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| DOI: | 10.1111/srt.13586 |