دورية أكاديمية
Using an economic simulation model to identify key drivers of profitability and estimate the environmental sustainability impact of immunization against gonadotropin-releasing factor (GnRF) in male and female pigs intended for market.
| العنوان: | Using an economic simulation model to identify key drivers of profitability and estimate the environmental sustainability impact of immunization against gonadotropin-releasing factor (GnRF) in male and female pigs intended for market. |
|---|---|
| المؤلفون: | Poulsen Nautrup B; EAH-Consulting, Aachen, Germany. Electronic address: bpn@EAH-Consulting.de., Van Vlaenderen I; CHESS, Bonheiden, Belgium., Mah CK; Zoetis, Parsippany, NJ, USA., Aldaz A; Zoetis, Parsippany, NJ, USA. |
| المصدر: | Research in veterinary science [Res Vet Sci] 2024 Mar; Vol. 168, pp. 105154. Date of Electronic Publication: 2024 Jan 11. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: British Veterinary Association Country of Publication: England NLM ID: 0401300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2661 (Electronic) Linking ISSN: 00345288 NLM ISO Abbreviation: Res Vet Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : British Veterinary Association Original Publication: Oxford. |
| مواضيع طبية MeSH: | Immunization*/veterinary , Vaccination*/veterinary, Swine ; Female ; Male ; Animals ; Gonadotropin-Releasing Hormone ; Weight Gain ; Gonadotropins |
| مستخلص: | An existing model was used to identify key drivers of profitability and estimate the impact on environmental sustainability when immunizing finishing pigs against GnRF with Improvac®. The model estimated performance and economic differences between immunized (IM) and non-IM pigs from the perspective of producers and packers, based on two recent meta-analyses in male and female pigs. It was populated with data from 9 countries in four continents (Europe, Asia, North and Latin-America). One-way sensitivity analyses (OWSA) were used to define key drivers of profitability. When changing the country specific input data over a range of ±20%, most OWSA did not reverse the mathematical sign of incremental net return between IM and non-IM pigs as calculated in base case analyses. Only the difference in feed conversion rate between IM and untreated female pigs was a key driver of profitability. The parameters with the highest impact on outcomes were similar across countries and expectable (feed costs), or explainable (parameters with statistical differences between IM and non-IM pigs in meta-analyses). In both single-gender herds, Improvac® reduced the environmental impact of pig production by improving feed efficiency (FE), the key driver of environmental burden. In a 50/50 mixed gender herd, IM pigs consumed less feed and gained more weight in 7 out of 9 countries; in the other two countries the FE calculated for the additional weight gain in IM pigs was >1.00, i.e., each additional kilogram of weight gain was associated with less than one additional kilogram of feed consumed. Competing Interests: Declaration of competing interest This study was supported by an unrestricted grant from Zoetis. At the time the study was conducted, Barbara Poulsen Nautrup and Ilse Van Vlaenderen were paid external consultants to Zoetis. ChoewKong Mah and Alvaro Aldaz were employees of Zoetis. (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Environmental sustainability; Immunization against GnRF; Improvac®; Key drivers of profitability |
| المشرفين على المادة: | 33515-09-2 (Gonadotropin-Releasing Hormone) 0 (Gonadotropins) |
| تواريخ الأحداث: | Date Created: 20240130 Date Completed: 20240214 Latest Revision: 20240214 |
| رمز التحديث: | 20240214 |
| DOI: | 10.1016/j.rvsc.2024.105154 |
| PMID: | 38290405 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1532-2661 |
|---|---|
| DOI: | 10.1016/j.rvsc.2024.105154 |