دورية أكاديمية

[Obstetrical outcome of renal transplant patients followed in a type III maternity hospital. Retrospective study from 2000 to 2020].

التفاصيل البيبلوغرافية
العنوان: [Obstetrical outcome of renal transplant patients followed in a type III maternity hospital. Retrospective study from 2000 to 2020].
عنوان ترانسليتريتد: Devenir obstétrical des patientes transplantées rénales suivies dans une maternité de type III. Étude rétrospective de 2000 à 2020.
المؤلفون: Reitz A; Service d'obstétrique, CHU de Clermont-Ferrand - Site Estaing, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France., Rouzaire M; CIC 1405 unité CRECHE, Inserm, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France., Cahierc R; Service d'obstétrique, CHU de Clermont-Ferrand - Site Estaing, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France., Pereira B; Unité de biostatistiques, DRCI, CHU de Clermont-Ferrand, 58, rue Montalembert, 63000 Clermont-Ferrand cedex, France., Lemal R; Service d'hématologie clinique, CHU de Clermont-Ferrand - Site Gabriel-Montpied, 58, rue Montalembert, 63000 Clermont-Ferrand cedex 1, France., Garrouste C; Service de néphrologie, CHU de Clermont-Ferrand - Site Gabriel-Montpied, 58, rue Montalembert, 63000 Clermont-Ferrand cedex 1, France., Gallot D; Service d'obstétrique, CHU de Clermont-Ferrand - Site Estaing, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France; CIC 1405 unité CRECHE, Inserm, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France; CNRS UMR 6293, Inserm U1103, GReD, université Clermont Auvergne, 63000 Clermont-Ferrand, France. Electronic address: dgallot@chu-clermontferrand.fr.
المصدر: Gynecologie, obstetrique, fertilite & senologie [Gynecol Obstet Fertil Senol] 2024 Jun; Vol. 52 (6), pp. 391-397. Date of Electronic Publication: 2024 Feb 01.
نوع المنشور: English Abstract; Journal Article
اللغة: French
بيانات الدورية: Publisher: Elsevier Masson SAS Country of Publication: France NLM ID: 101693805 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-7189 (Electronic) Linking ISSN: 24687189 NLM ISO Abbreviation: Gynecol Obstet Fertil Senol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Issy-les-Moulineaux : Elsevier Masson SAS, [2017]-
مواضيع طبية MeSH: Kidney Transplantation* , Pregnancy Complications*/epidemiology , Pregnancy Outcome* , Cesarean Section*/statistics & numerical data, Humans ; Female ; Pregnancy ; Retrospective Studies ; Adult ; Infant, Newborn ; Hospitals, Maternity ; Pre-Eclampsia/epidemiology ; Graft Rejection/epidemiology ; Gestational Age ; Diabetes, Gestational/epidemiology ; Birth Weight ; Live Birth
مستخلص: Aim: To describe pregnancy outcome of kidney transplant patients till 1 year postpartum.
Methods: This retrospective, monocentric study included 15 kidney transplant patients who presented 18 pregnancies, between January 2000 and January 2020. For each of them, we searched for possible obstetrical, fetal and renal complications and we evaluated renal function before, during and after pregnancy.
Results: The live birth rate was 84% (16/19) with an average gestational age at delivery of 37 weeks of gestation. The rate of prematurity was 50% (8/16), gestational diabetes was 16.6% (3/18) and preeclampsia was 27.7% (5/18). Cesarean section was performed in 61.1% (11/18) of cases including, 81.8% (9/11) unplanned surgery. The average birth weight was 2635 grams and 37.5% (6/16) of the newborn were small for gestational age. All patients had stable renal function before conception of pregnancy. We noticed two acute graft rejection during pregnancy with only one resulting in graft loss. Four patients had a reduced graft function in 12months of the postpartum.
Conclusion: Risk of maternal, fetal and renal complications remained high in kidney transplant recipients. Pregnancy should be carefully planned in transplanted women associated with adequate follow-up according to clinical guidelines (normal renal function and blood pressure without proteinuria before pregnancy, no recent graft rejection, period of one year after transplant respected and no teratogenic treatment in the month before pregnancy).
(Copyright © 2024 Elsevier Masson SAS. All rights reserved.)
فهرسة مساهمة: Keywords: Complications maternofœtales; Fonction rénale; Grossesse; Maternal and foetal complications; Pregnancy; Renal function; Renal transplantation; Transplantation rénale
تواريخ الأحداث: Date Created: 20240131 Date Completed: 20240609 Latest Revision: 20240609
رمز التحديث: 20240610
DOI: 10.1016/j.gofs.2024.01.011
PMID: 38296107
قاعدة البيانات: MEDLINE
الوصف
تدمد:2468-7189
DOI:10.1016/j.gofs.2024.01.011