دورية أكاديمية
Association of Cutaneous Keloids, Hypertrophic Scarring, and Fibrosis with Risk of Postoperative Proliferative Vitreoretinopathy.
| العنوان: | Association of Cutaneous Keloids, Hypertrophic Scarring, and Fibrosis with Risk of Postoperative Proliferative Vitreoretinopathy. |
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| المؤلفون: | Mammo DA; Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: danny.mammo24@gmail.com., Wai K; Byers Eye Institute, Stanford Health Care, Palo Alto, California., Rahimy E; Byers Eye Institute, Stanford Health Care, Palo Alto, California., Pan CK; Byers Eye Institute, Stanford Health Care, Palo Alto, California., Srivastava SK; Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio., Mruthyunjaya P; Byers Eye Institute, Stanford Health Care, Palo Alto, California. |
| المصدر: | Ophthalmology [Ophthalmology] 2024 Aug; Vol. 131 (8), pp. 961-966. Date of Electronic Publication: 2024 Feb 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2000- : New York : Elsevier Original Publication: Rochester, Minn., American Academy of Ophthalmology. |
| مواضيع طبية MeSH: | Keloid* , Vitreoretinopathy, Proliferative*/surgery , Vitreoretinopathy, Proliferative*/diagnosis , Vitreoretinopathy, Proliferative*/etiology , Cicatrix, Hypertrophic*/etiology , Cicatrix, Hypertrophic*/epidemiology , Fibrosis* , Retinal Detachment*/surgery , Retinal Detachment*/diagnosis , Vitrectomy*/adverse effects , Postoperative Complications*, Humans ; Female ; Male ; Retrospective Studies ; Middle Aged ; Adult ; Aged ; Risk Factors ; Scleral Buckling |
| مستخلص: | Purpose: To assess an association between cutaneous keloids, hypertrophic scarring, and fibrosis (KHF) and risk of postoperative proliferative vitreoretinopathy (PVR) after rhegmatogenous retinal detachment (RRD) repair. Design: Retrospective, population-based cohort study. Participants: Patients aged ≥ 18 years who underwent initial retinal detachment (RD) repair with pars plana vitrectomy with or without scleral buckle (SB) (Current Procedural Terminology [CPT] 67108), pneumatic retinopexy (67110), and primary SB (67107) from January 1, 2003, to March 1, 2023. Methods: A de-identified electronic health record database through TriNetX, a global health research network, was used to analyze patients. Patients were queried for International Classification of Diseases, 10 th Revision (ICD-10) codes L91.0 (hypertrophic scar) and L90.5 (scar conditions and fibrosis of skin). Frequency of subsequent diagnosis of PVR (H35.2) and CPT codes for secondary surgery including complex RD repair (67113) were determined. Patients with proliferative diabetic retinopathy (PDR) (ICD-10 H10.35/H11.35) were excluded. Descriptive statistics (Z-test) and propensity score matching (PSM) were used to match for age, sex, and race. Main Outcome Measures: Prevalence of H35.2 and CPT 67113 within 180 days after RRD repair in the KHF cohort versus the non-KHF cohort. Results: Among patients with CPT 67108, 1061 in each cohort (KHF and non-KHF) were analyzed after PSM. The mean (standard deviation) age was 60.7 (15.2) years. Within 180 days, 10.1% of patients in the KHF cohort and 3.4% in the non-KHF cohort had a diagnosis of PVR (H35.2) (P < 0.001, odds ratio [OR], 3.2; 95% confidence interval [CI], 2.13-4.71). A total of 8.3% of patients in the KHF cohort and 5.4% of patients in the non-KHF cohort underwent complex RD repair (CPT 67113) (P = 0.008; OR, 3.2; 95% CI, 1.13-2.25). When including all RD repair types (CPT 67108, 67110, 67107), the rate of PVR diagnosis was still significantly greater in the KHF cohort than in the non-KHF cohort (9.0% vs 4.2%, P < 0.01; OR, 2.28; 95% CI, 1.64-3.16). Conclusions: A dermatologic history of KHF may be a risk factor for PVR after RD repair. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Copyright © 2024 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Dermatology; Hypertrophic scars; PVR; Proliferative vitreoretinopathy; Retinal detachment |
| تواريخ الأحداث: | Date Created: 20240131 Date Completed: 20240719 Latest Revision: 20240719 |
| رمز التحديث: | 20240720 |
| DOI: | 10.1016/j.ophtha.2024.01.032 |
| PMID: | 38296203 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1549-4713 |
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| DOI: | 10.1016/j.ophtha.2024.01.032 |