Editorial & Opinion
Editorial Commentary: Low-Grade Infections May Contribute to Anterior Cruciate Ligament Reconstruction Graft Failure.
| العنوان: | Editorial Commentary: Low-Grade Infections May Contribute to Anterior Cruciate Ligament Reconstruction Graft Failure. |
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| المؤلفون: | Burnett Z; The Ohio State University., Stoodley P; The Ohio State University., Flanigan DC; The Ohio State University. |
| المصدر: | Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association [Arthroscopy] 2024 Feb; Vol. 40 (2), pp. 409-411. |
| نوع المنشور: | Editorial; Comment |
| اللغة: | English |
| بيانات الدورية: | Publisher: W.B. Saunders Co Country of Publication: United States NLM ID: 8506498 Publication Model: Print Cited Medium: Internet ISSN: 1526-3231 (Electronic) Linking ISSN: 07498063 NLM ISO Abbreviation: Arthroscopy Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia, PA : W.B. Saunders Co. Original Publication: [New York, N.Y.] : Raven Press, [c1985- |
| مواضيع طبية MeSH: | Anterior Cruciate Ligament Injuries*/surgery , Anterior Cruciate Ligament Reconstruction*, Humans ; Anterior Cruciate Ligament/surgery ; DNA, Bacterial ; Tibia/surgery |
| مستخلص: | The etiology of anterior cruciate ligament (ACL) reconstruction failure is often multifactorial, and the role of subclinical bacterial colonization in ACL reconstruction failure has not been fully elucidated. Although the presence of bacterial metabolism in and of itself does not indicate true clinical infection, low-grade infections may contribute to ACL reconstruction graft failure. Bacterial biofilms on soft tissue grafts are shown to change the crimp patterns of collagen and lower graft load to failure. In addition, bacterial DNA has been reported in 80-87% of failed ACL grafts during revision surgery compared to only 20% of primary ACL grafts. Also, higher bacterial DNA concentration is associated with tibial tunnel widening. Further study is needed to establish if any causal relationship between bacterial colonization and ACL graft failure exists. But it does seem that the circumstantial evidence is pointing to such a relationship. (Copyright © 2023 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.) |
| التعليقات: | Comment on: Arthroscopy. 2024 Feb;40(2):400-408. (PMID: 37437788) |
| المشرفين على المادة: | 0 (DNA, Bacterial) |
| تواريخ الأحداث: | Date Created: 20240131 Date Completed: 20240214 Latest Revision: 20240226 |
| رمز التحديث: | 20240227 |
| DOI: | 10.1016/j.arthro.2023.07.030 |
| PMID: | 38296444 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1526-3231 |
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| DOI: | 10.1016/j.arthro.2023.07.030 |