دورية أكاديمية

Association of triglyceride‑glucose index in branch retinal vein occlusion.

التفاصيل البيبلوغرافية
العنوان: Association of triglyceride‑glucose index in branch retinal vein occlusion.
المؤلفون: Aslan Sirakaya H; Department of Internal Medicine, Health Science University, The Kayseri City Hospital, Kayseri, Turkey. hasirakaya@gmail.com., Sirakaya E; Department of Ophthalmology, Health Science University, The Kayseri City Hospital, Kayseri, Turkey.
المصدر: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 2024 Jul; Vol. 262 (7), pp. 2067-2072. Date of Electronic Publication: 2024 Feb 01.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 8205248 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-702X (Electronic) Linking ISSN: 0721832X NLM ISO Abbreviation: Graefes Arch Clin Exp Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin ; New York : Springer-Verlag, c1982-
مواضيع طبية MeSH: Retinal Vein Occlusion*/diagnosis , Retinal Vein Occlusion*/blood , Triglycerides*/blood , Blood Glucose*/metabolism , ROC Curve*, Humans ; Male ; Female ; Middle Aged ; Biomarkers/blood ; Risk Factors ; Aged ; Fluorescein Angiography/methods
مستخلص: Background: To investigate the association between the triglyceride-glucose (TyG) index and newly diagnosed branch retinal vein occlusion (BRVO) in patients.
Methods: The study included 57 individuals with BRVO and a control group comprising 50 healthy volunteers matched for age and gender. Detailed eye examinations were conducted, and various blood biochemistry and hematological parameters were recorded. The TyG index was calculated using fasting plasma glucose and triglyceride values.
Results: The mean age was 61.4 ± 9.6 years for the BRVO group and 60.6 ± 10.3 years for the control group. The TyG values were significantly higher in the BRVO group when compared to the control group (8.84 ± 0.41 vs. 8.52 ± 0.29, p < 0.001). Multivariate analysis revealed that the TyG index independently predicted BRVO (odds ratio = 2.58, 95% confidence interval = 1.69-3.93; p < 0.001). In receiver operating characteristics analysis, the TyG index had an area under the curve of 0.749, and a TyG index higher than 8.52 predicted BRVO with 83% sensitivity and 70% specificity.
Conclusions: This study establishes a significant association between an elevated TyG index and BRVO. Consequently, the TyG index could serve as a valuable predictive tool for identifying individuals at risk for BRVO.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Atherosclerosis; BRVO; Branch retinal vein occlusion; Triglyceride-glucose index; TyG index
المشرفين على المادة: 0 (Triglycerides)
0 (Blood Glucose)
0 (Biomarkers)
تواريخ الأحداث: Date Created: 20240201 Date Completed: 20240703 Latest Revision: 20240718
رمز التحديث: 20240718
مُعرف محوري في PubMed: PMC11222183
DOI: 10.1007/s00417-024-06376-2
PMID: 38300335
قاعدة البيانات: MEDLINE
الوصف
تدمد:1435-702X
DOI:10.1007/s00417-024-06376-2