دورية أكاديمية
Elucidating the Mode of Action of Hybrid Nanoparticles of Cu/Zn Against Copper-Tolerant Xanthomonas euvesicatoria .
| العنوان: | Elucidating the Mode of Action of Hybrid Nanoparticles of Cu/Zn Against Copper-Tolerant Xanthomonas euvesicatoria . |
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| المؤلفون: | Carvalho R; Department of Plant Pathology, University of Florida, Gainesville, FL 32611., Tapia JH; Department of Plant Pathology, University of Florida, Gainesville, FL 32611., Minsavage GV; Department of Plant Pathology, University of Florida, Gainesville, FL 32611., Jones JB; Department of Plant Pathology, University of Florida, Gainesville, FL 32611., Paret ML; Department of Plant Pathology, University of Florida, Gainesville, FL 32611.; North Florida Research and Education Center, University of Florida, Quincy, FL 32251. |
| المصدر: | Phytopathology [Phytopathology] 2024 Jun; Vol. 114 (6), pp. 1206-1214. Date of Electronic Publication: 2024 Jun 07. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Phytopathological Society] Country of Publication: United States NLM ID: 9427222 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0031-949X (Print) Linking ISSN: 0031949X NLM ISO Abbreviation: Phytopathology Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [St. Paul, Minn., etc., American Phytopathological Society] |
| مواضيع طبية MeSH: | Xanthomonas*/drug effects , Xanthomonas*/genetics , Copper*/pharmacology , Zinc*/pharmacology , Plant Diseases*/microbiology, Metal Nanoparticles/chemistry ; Nanoparticles/chemistry |
| مستخلص: | The widespread presence of tolerance to copper in Xanthomonas species has resulted in the need to develop alternative approaches to control plant diseases caused by xanthomonads. In recent years, nanotechnological approaches have resulted in the identification of novel materials to control plant pathogens. With many metal-based nanomaterials having shown promise for disease control, an important question relates to the mode of action of these new materials. In this study, we used several approaches, such as scanning electron microscopy, propidium monoazide quantitative polymerase chain reaction, epifluorescence microscopy, and RNA sequencing to elucidate the mode of action of a Cu/Zn hybrid nanoparticle against copper-tolerant strains of Xanthomonas euvesicatoria. We demonstrate that Cu/Zn did not activate copper resistance genes (i.e., copA and copB ) in the copper-tolerant bacterium but functioned by disrupting the bacterial cell structure and perturbing important biological processes such as cell respiration and chemical homeostasis. Competing Interests: The author(s) declare no conflict of interest. |
| فهرسة مساهمة: | Keywords: bacterial spot; mode-of-action; nanotechnology |
| المشرفين على المادة: | 789U1901C5 (Copper) J41CSQ7QDS (Zinc) |
| تواريخ الأحداث: | Date Created: 20240201 Date Completed: 20240626 Latest Revision: 20240626 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1094/PHYTO-09-23-0339-R |
| PMID: | 38302452 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0031-949X |
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| DOI: | 10.1094/PHYTO-09-23-0339-R |