دورية أكاديمية
Viral Keratitis, Surgical Intervention in Viral Keratitis, Challenges in Diagnosis and Treatment of Viral Keratitis, HSV, HZV.
| العنوان: | Viral Keratitis, Surgical Intervention in Viral Keratitis, Challenges in Diagnosis and Treatment of Viral Keratitis, HSV, HZV. |
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| المؤلفون: | Venugopal A; Department of Cornea & Refractive services, Aravind Eye, Hospital and postgraduate institute of Ophthalmology, Tirunelveli, Tamil Nadu, India., Christy J; Department of Cornea & Refractive services, Aravind Eye Hospital, Pondicherry, India., Raut V; Post-Graduate in Ophthalmology Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India., P P; Post-Graduate in Ophthalmology Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India., Patwardhan V; Medical Consultant, Cornea and Refractive Services, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India., V V; Fellow in Cornea and Refractive surgery, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India., Madkaikar A; Department of Cornea & Refractive services, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India., P M; Department of Cornea & Refractive services, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India., Meenakshi R; Chief medical officer, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India., Ramakrishnan R; Post-Graduate in Ophthalmology Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India. |
| المصدر: | Seminars in ophthalmology [Semin Ophthalmol] 2024 Jul; Vol. 39 (5), pp. 340-352. Date of Electronic Publication: 2024 Feb 01. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 8610759 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5205 (Electronic) Linking ISSN: 08820538 NLM ISO Abbreviation: Semin Ophthalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: [Orlando, FL] : Grune & Stratton, [c1986- |
| مواضيع طبية MeSH: | Eye Infections, Viral*/diagnosis , Eye Infections, Viral*/virology , Eye Infections, Viral*/drug therapy , Eye Infections, Viral*/surgery , Antiviral Agents*/therapeutic use , Keratitis, Herpetic*/diagnosis , Keratitis, Herpetic*/drug therapy , Keratitis, Herpetic*/surgery , Keratitis, Herpetic*/virology, Humans ; Herpes Zoster Ophthalmicus/diagnosis ; Herpes Zoster Ophthalmicus/drug therapy ; Herpes Zoster Ophthalmicus/virology ; Ophthalmologic Surgical Procedures/methods |
| مستخلص: | Viral keratitis is a significant cause of ocular morbidity and visual impairment worldwide. In recent years, there has been a growing understanding of the pathogenesis, clinical manifestations, and diagnostic modalities for viral keratitis. The most common viral pathogens associated with this condition are adenovirus, herpes simplex (HSV), and varicella-zoster virus (VZV). However, emerging viruses such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), and Vaccinia virus can also cause keratitis. Non-surgical interventions are the mainstay of treatment for viral keratitis. Antiviral agents such as Acyclovir, Ganciclovir, and trifluridine have effectively reduced viral replication and improved clinical outcomes. Additionally, adjunctive measures such as lubrication, corticosteroids, and immunomodulatory agents have alleviated symptoms by reducing inflammation and facilitating tissue repair. Despite these conservative approaches, some cases of viral keratitis may progress to severe forms, leading to corneal scarring, thinning, or perforation. In such instances, surgical intervention becomes necessary to restore corneal integrity and visual function. This review article aims to provide an overview of the current perspectives and surgical interventions in managing viral keratitis. The choice of surgical technique depends on the extent and severity of corneal involvement. As highlighted in this article, on-going research and advancements in surgical interventions hold promise for further improving outcomes in patients with viral keratitis. |
| فهرسة مساهمة: | Keywords: Corneal neurotization; Corneal vascularization; HSV; Keratoplasty for viral keratitis; VZV; Viral keratitis |
| المشرفين على المادة: | 0 (Antiviral Agents) |
| تواريخ الأحداث: | Date Created: 20240202 Date Completed: 20240529 Latest Revision: 20240529 |
| رمز التحديث: | 20240530 |
| DOI: | 10.1080/08820538.2024.2309533 |
| PMID: | 38303587 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1744-5205 |
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| DOI: | 10.1080/08820538.2024.2309533 |