دورية أكاديمية
Comparison of the effect of topical triamcinolone 0.1% cream with sulfur 2.0% cream in the treatment of patients with hand eczema: A randomized controlled trial.
العنوان: | Comparison of the effect of topical triamcinolone 0.1% cream with sulfur 2.0% cream in the treatment of patients with hand eczema: A randomized controlled trial. |
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المؤلفون: | Asilian A; Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.; Department of Dermatology, Skin and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Mohammadian P; Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.; Department of Dermatology, Skin and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Hosseini SM; Department of Biostatistics & Epidemiology, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran., Heidaripour F; Sina Daru International, Suba Laboratory, Tehran, Iran., Yekta A; Sina Daru International, Suba Laboratory, Tehran, Iran., Nateghi MR; Sarem Academy of Sciences, Sarem Hospital, Tehran, Iran. |
المصدر: | Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 May; Vol. 23 (5), pp. 1753-1757. Date of Electronic Publication: 2024 Feb 04. |
نوع المنشور: | Journal Article; Randomized Controlled Trial; Comparative Study |
اللغة: | English |
بيانات الدورية: | Publisher: Blackwell Science Country of Publication: England NLM ID: 101130964 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-2165 (Electronic) Linking ISSN: 14732130 NLM ISO Abbreviation: J Cosmet Dermatol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Oxford, UK : Blackwell Science, c2002- |
مواضيع طبية MeSH: | Eczema*/drug therapy , Hand Dermatoses*/drug therapy , Skin Cream*/administration & dosage , Skin Cream*/adverse effects , Severity of Illness Index* , Triamcinolone*/administration & dosage , Triamcinolone*/adverse effects , Sulfur*/administration & dosage , Sulfur*/adverse effects, Humans ; Male ; Female ; Adult ; Middle Aged ; Treatment Outcome ; Young Adult ; Pruritus/drug therapy ; Pruritus/etiology ; Administration, Cutaneous ; Glucocorticoids/administration & dosage ; Glucocorticoids/adverse effects |
مستخلص: | Background: Hand eczema (HE) is a common and heterogeneous condition. It has a wide range of etiologies and clinical manifestations. In this study the efficacy of triamcinolone 0.1% cream and sulfur 2% creams was compared in treating patients with HE. Methods: This randomized, triple-blind clinical trial was performed on 70 patients with HE (including 70 right and 70 left hands). In this study, two creams were used including triamcinolone 0.1% and sulfur 2.0%. Patients were treated with these creams twice a day (once in every 12 h) for 4 weeks. Follow-up was 4 weeks after treatment. Hand Eczema Severity Index (HECSI), itching, dryness, burning sensation, and erythema scores were collected three times during the study and compared between treatment regimens. Results: Findings showed that both triamcinolone (0.1%) and sulfur (2.0%) creams could significantly reduce the scores of HECSI, itching, dryness, burning sensation, and erythema, and the therapeutic effects lasted for at least 4 weeks after cessation of topical treatment. Conclusion: Topical sulfur cream (2.0%) is as effective as triamcinolone (0.1%) cream in treatment of HE without any prominent adverse reactions. (© 2024 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.) |
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فهرسة مساهمة: | Keywords: hand eczema; hand eczema severity index; randomized controlled trial; sulfur cream; triamcinolone cream |
المشرفين على المادة: | 1ZK20VI6TY (Triamcinolone) 70FD1KFU70 (Sulfur) 0 (Glucocorticoids) |
تواريخ الأحداث: | Date Created: 20240205 Date Completed: 20240424 Latest Revision: 20240508 |
رمز التحديث: | 20240509 |
DOI: | 10.1111/jocd.16208 |
PMID: | 38311842 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1473-2165 |
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DOI: | 10.1111/jocd.16208 |