دورية أكاديمية
Acute kidney injury in neonates with hypoxic ischemic encephalopathy based on serum creatinine decline compared to KDIGO criteria.
العنوان: | Acute kidney injury in neonates with hypoxic ischemic encephalopathy based on serum creatinine decline compared to KDIGO criteria. |
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المؤلفون: | Ahn HC; Division of Pediatric Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA. haejun.ahn@swedish.org.; Pediatric Nephrology, Swedish Health, Seattle, WA, USA. haejun.ahn@swedish.org., Frymoyer A; Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Boothroyd DB; Quantitative Sciences Unit, Stanford University School of Medicine, Palo Alto, CA, USA., Bonifacio S; Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Sutherland SM; Division of Pediatric Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA., Chock VY; Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA. |
المصدر: | Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2024 Sep; Vol. 39 (9), pp. 2789-2796. Date of Electronic Publication: 2024 Feb 07. |
نوع المنشور: | Journal Article; Comparative Study |
اللغة: | English |
بيانات الدورية: | Publisher: Springer International Country of Publication: Germany NLM ID: 8708728 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-198X (Electronic) Linking ISSN: 0931041X NLM ISO Abbreviation: Pediatr Nephrol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Berlin : Springer International Original Publication: Berlin : Springer International, c1987- |
مواضيع طبية MeSH: | Acute Kidney Injury*/blood , Acute Kidney Injury*/etiology , Acute Kidney Injury*/diagnosis , Acute Kidney Injury*/mortality , Acute Kidney Injury*/therapy , Hypoxia-Ischemia, Brain*/diagnosis , Hypoxia-Ischemia, Brain*/blood , Hypoxia-Ischemia, Brain*/therapy , Hypoxia-Ischemia, Brain*/complications , Hypoxia-Ischemia, Brain*/mortality , Creatinine*/blood, Humans ; Infant, Newborn ; Retrospective Studies ; Female ; Male ; Hypothermia, Induced ; Severity of Illness Index ; Magnetic Resonance Imaging ; Length of Stay/statistics & numerical data |
مستخلص: | Background: Neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia (HIE + TH) are at risk for acute kidney injury (AKI). The standardized Kidney Disease Improving Global Outcomes (KDIGO) criteria identifies AKI based on a rise in serum creatinine (SCr) or reduced urine output. This definition is challenging to apply in neonates given the physiologic decline in SCr during the first week of life. Gupta et al. proposed alternative neonatal criteria centered on rate of SCr decline. This study aimed to compare the rate of AKI based on KDIGO and Gupta in neonates with HIE and to examine associations with mortality and morbidity. Methods: A retrospective review was performed of neonates with moderate to severe HIE + TH from 2008 to 2020 at a single center. AKI was assessed in the first 7 days after birth by KDIGO and Gupta criteria. Mortality, brain MRI severity of injury, length of stay, and duration of respiratory support were compared between AKI groups. Results: Among 225 neonates, 64 (28%) met KDIGO, 69 (31%) neonates met Gupta but not KDIGO, and 92 (41%) did not meet either definition. Both KDIGO-AKI and GuptaOnly-AKI groups had an increased risk of the composite mortality and/or moderate/severe brain MRI injury along with longer length of stay and prolonged duration of respiratory support compared to those without AKI. Conclusions: AKI in neonates with HIE + TH was common and varied by definition. The Gupta definition based on rate of SCr decline identified additional neonates not captured by KDIGO criteria who are at increased risk for adverse outcomes. Incorporating the rate of SCr decline into the neonatal AKI definition may increase identification of clinically relevant kidney injury in neonates with HIE + TH. (© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.) |
References: | Kirkley MJ, Boohaker L, Griffin R et al (2019) Acute kidney injury in neonatal encephalopathy: an evaluation of the AWAKEN database. Pediatr Nephrol 34:169–176. https://doi.org/10.1007/s00467-018-4068-2. (PMID: 10.1007/s00467-018-4068-230155763) Robertsson Grossmann K, Vishnevskaya L, Diaz Ruiz S et al (2023) Kidney outcomes in early adolescence following perinatal asphyxia and hypothermia-treated hypoxic-ischaemic encephalopathy. Pediatr Nephrol 38:1205–1214. https://doi.org/10.1007/s00467-022-05705-z. (PMID: 10.1007/s00467-022-05705-z35976440) Selewski DT, Jordan BK, Askenazi DJ et al (2013) Acute kidney injury in asphyxiated newborns treated with therapeutic hypothermia. J Pediatr 162:725-729.e1. https://doi.org/10.1016/j.jpeds.2012.10.002. (PMID: 10.1016/j.jpeds.2012.10.00223149172) Alaro D, Bashir A, Musoke R, Wanaiana L (2014) Prevalence and outcomes of acute kidney injury in term neonates with perinatal asphyxia. Afr Health Sci 14:682–688. https://doi.org/10.4314/ahs.v14i3.26. (PMID: 10.4314/ahs.v14i3.26253528894209658) Sutherland SM, Ji J, Sheikhi FH et al (2013) AKI in hospitalized children: epidemiology and clinical associations in a national cohort. Clin J Am Soc Nephrol 8:1661–1669. https://doi.org/10.2215/CJN.00270113. (PMID: 10.2215/CJN.00270113238333123789331) Kwiatkowski DM, Sutherland SM (2017) Acute kidney injury in pediatric patients. Best Pract Res Clin Anaesthesiol 31:427–439. https://doi.org/10.1016/j.bpa.2017.08.007. (PMID: 10.1016/j.bpa.2017.08.00729248148) Sigurjonsdottir VK, Chaturvedi S, Mammen C, Sutherland SM (2018) Pediatric acute kidney injury and the subsequent risk for chronic kidney disease: is there cause for alarm? Pediatr Nephrol 33:2047–2055. https://doi.org/10.1007/s00467-017-3870-6. (PMID: 10.1007/s00467-017-3870-629374316) Chawla LS, Amdur RL, Amodeo S et al (2011) The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int 79:1361–1369. https://doi.org/10.1038/ki.2011.42. (PMID: 10.1038/ki.2011.42214306403257034) Askenazi DJ, Ambalavanan N, Goldstein SL (2009) Acute kidney injury in critically ill newborns: what do we know? What do we need to learn? Pediatr Nephrol 24:265–274. https://doi.org/10.1007/s00467-008-1060-2. (PMID: 10.1007/s00467-008-1060-2190826342755786) Chertow GM, Burdick E, Honour M et al (2005) Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16:3365–3370. https://doi.org/10.1681/ASN.2004090740. (PMID: 10.1681/ASN.200409074016177006) Meena J, Mathew G, Kumar J, Chanchlani R (2023) Incidence of acute kidney injury in hospitalized children: a meta-analysis. Pediatrics 151:e2022058823. https://doi.org/10.1542/peds.2022-058823. (PMID: 10.1542/peds.2022-05882336646649) Alkandari O, Eddington KA, Hyder A et al (2011) Acute kidney injury is an independent risk factor for pediatric intensive care unit mortality, longer length of stay and prolonged mechanical ventilation in critically ill children: a two-center retrospective cohort study. Crit Care 15:R146. https://doi.org/10.1186/cc10269. (PMID: 10.1186/cc10269216636163219018) Cavallin F, Rubin G, Vidal E et al (2020) Prognostic role of acute kidney injury on long-term outcome in infants with hypoxic-ischemic encephalopathy. Pediatr Nephrol 35:477–483. https://doi.org/10.1007/s00467-019-04406-4. (PMID: 10.1007/s00467-019-04406-431828471) Sarkar S, Askenazi DJ, Jordan BK et al (2014) Relationship between acute kidney injury and brain MRI findings in asphyxiated newborns after therapeutic hypothermia. Pediatr Res 75:431–435. https://doi.org/10.1038/pr.2013.230. (PMID: 10.1038/pr.2013.23024296799) Gupta C, Massaro AN, Ray PE (2016) A new approach to define acute kidney injury in term newborns with hypoxic ischemic encephalopathy. Pediatr Nephrol 31:1167–1178. https://doi.org/10.1007/s00467-016-3317-5. (PMID: 10.1007/s00467-016-3317-5268577104882244) Gupta BD, Sharma P, Bagla J et al (2005) Renal failure in asphyxiated neonates. Indian Pediatr 42:928–934. (PMID: 16208054) Zappitelli M, Ambalavanan N, Askenazi DJ et al (2017) Developing a neonatal acute kidney injury research definition: a report from the NIDDK neonatal AKI workshop. Pediatr Res 82:569–573. https://doi.org/10.1038/pr.2017.136. (PMID: 10.1038/pr.2017.136286047609673450) Carmody JB, Swanson JR, Rhone ET, Charlton JR (2014) Recognition and reporting of AKI in very low birth weight infants. Clin J Am Soc Nephrol 9:2036–2043. https://doi.org/10.2215/CJN.05190514. (PMID: 10.2215/CJN.05190514252804974255405) Shankaran S, Laptook AR, Ehrenkranz RA et al (2005) Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 353:1574–1584. https://doi.org/10.1056/NEJMcps050929. (PMID: 10.1056/NEJMcps05092916221780) Pavageau L, Sánchez PJ, Steven Brown L, Chalak LF (2020) Inter-rater reliability of the modified Sarnat examination in preterm infants at 32–36 weeks’ gestation. Pediatr Res 87:697–702. https://doi.org/10.1038/s41390-019-0562-x. (PMID: 10.1038/s41390-019-0562-x31493776) Jetton JG, Boohaker LJ, Sethi SK et al (2017) Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study. Lancet Child Adolesc Health 1:184–194. https://doi.org/10.1016/S2352-4642(17)30069-X. (PMID: 10.1016/S2352-4642(17)30069-X297323965933049) Barkovich AJ, Hajnal BL, Vigneron D et al (1998) Prediction of neuromotor outcome in perinatal asphyxia: evaluation of MR scoring systems. AJNR Am J Neuroradiol 19:143–149. (PMID: 94321728337350) Perazzo S, Revenis M, Massaro A et al (2020) A new approach to recognize neonatal impaired kidney function. Kidney Int Rep 5:2301–2312. https://doi.org/10.1016/j.ekir.2020.09.043. (PMID: 10.1016/j.ekir.2020.09.043333051247710891) Mammen C, Al Abbas A, Skippen P et al (2012) Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: a prospective cohort study. Am J Kidney Dis 59:523–530. https://doi.org/10.1053/j.ajkd.2011.10.048. (PMID: 10.1053/j.ajkd.2011.10.04822206744) Coca SG, Singanamala S, Parikh CR (2012) Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis. Kidney Int 81:442–448. https://doi.org/10.1038/ki.2011.379. (PMID: 10.1038/ki.2011.37922113526) Pazandak C, McPherson C, Abubakar M et al (2020) Blood pressure profiles in infants with hypoxic ischemic encephalopathy (HIE), response to dopamine, and association with brain injury. Front Pediatr 8:512. https://doi.org/10.3389/fped.2020.00512. (PMID: 10.3389/fped.2020.00512329842217479124) |
فهرسة مساهمة: | Keywords: Acute kidney injury; Hypoxic ischemic encephalopathy; KDIGO; Neonatal; Neonatal asphyxia |
المشرفين على المادة: | AYI8EX34EU (Creatinine) |
تواريخ الأحداث: | Date Created: 20240207 Date Completed: 20240725 Latest Revision: 20240725 |
رمز التحديث: | 20240726 |
DOI: | 10.1007/s00467-024-06287-8 |
PMID: | 38326648 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1432-198X |
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DOI: | 10.1007/s00467-024-06287-8 |