دورية أكاديمية
أعرض في EDS

Bathing with wipes impregnated with chlorhexidine gluconate to prevent central line-associated bloodstream infection in critically ill patients: A systematic review with meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Bathing with wipes impregnated with chlorhexidine gluconate to prevent central line-associated bloodstream infection in critically ill patients: A systematic review with meta-analysis.
المؤلفون: Peixoto EAC; Faculdade Israelita de Ciências da Saúde Albert Einstein, Programa de Mestrado Profissional em Enfermagem, R. Comendador Elias Jafet, São Paulo, SP, Brazil. Electronic address: ericagpeixoto@hotmail.com., Poveda VB; Departamento de Enfermagem-Médico Cirúrgica, Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil. Electronic address: vbpoveda@usp.br., Gnatta JR; Departamento de Enfermagem-Médico Cirúrgica, Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil. Electronic address: juliana.gnatta@usp.br., Oliveira RA; Departamento de Enfermagem-Médico Cirúrgica, Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil. Electronic address: ramon.oliveira@usp.br.
المصدر: American journal of infection control [Am J Infect Control] 2024 Jun; Vol. 52 (6), pp. 731-738. Date of Electronic Publication: 2024 Feb 10.
نوع المنشور: Systematic Review; Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review
اللغة: English
بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 8004854 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3296 (Electronic) Linking ISSN: 01966553 NLM ISO Abbreviation: Am J Infect Control Subsets: MEDLINE
أسماء مطبوعة: Original Publication: St. Louis, Mosby
مواضيع طبية MeSH: Chlorhexidine*/administration & dosage , Chlorhexidine*/analogs & derivatives , Catheter-Related Infections*/prevention & control , Baths*/methods , Critical Illness*, Humans ; Anti-Infective Agents, Local/administration & dosage ; Intensive Care Units ; Catheterization, Central Venous/adverse effects
مستخلص: Background: Recommendations for different types of bathing to prevent central line-associated bloodstream infections (CLABSI) are still divergent. The objective of this study was to verify whether bed bathing with wipes impregnated with 2% chlorhexidine (CHG) compared to conventional bed bathing is more effective in preventing CLABSI.
Methods: Systematic review of the literature by consulting the electronic databases PubMed/Medline, Embase, CINAHL, Scopus, and Web of Science from the date of inception until July 1, 2023, with no language or time restrictions.
Results: A total of 84,462 studies were examined, of which 6 were included in the meta-analysis. Data from 20,188 critical care patients included in primary studies were analyzed. The meta-analysis found that bed bathing with wipes impregnated with 2% CHG reduced the risk of CLABSI by 48% compared to conventional bed bathing (risk ratio 0.52; 95% confidence interval, 0.37-0.73), and this is moderate-quality evidence. The reduction in length of stay in the intensive care unit and length of hospital stay as well as the risk of death were not significantly different between the study groups. Whether bed bathing with 2% CHG-impregnated wipes increases the occurrence of skin reactions is unclear.
Conclusions: This meta-analysis provides moderate-quality evidence that daily bathing with 2% CHG-impregnated wipes is safe and helps prevent CLABSI among adult intensive care unit patients.
(Copyright © 2024 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Central venous catheters; Critical care; Infection control
المشرفين على المادة: R4KO0DY52L (Chlorhexidine)
MOR84MUD8E (chlorhexidine gluconate)
0 (Anti-Infective Agents, Local)
تواريخ الأحداث: Date Created: 20240211 Date Completed: 20240511 Latest Revision: 20240808
رمز التحديث: 20240808
DOI: 10.1016/j.ajic.2024.01.019
PMID: 38342345
قاعدة البيانات: MEDLINE
الوصف
تدمد:1527-3296
DOI:10.1016/j.ajic.2024.01.019