دورية أكاديمية
Association between placental efficiency with anthropometry and nutritional phenotypes in full-term newborns from the 2010/2011 BRISA birth cohort.
| العنوان: | Association between placental efficiency with anthropometry and nutritional phenotypes in full-term newborns from the 2010/2011 BRISA birth cohort. |
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| المؤلفون: | Penteado MP; Universidade de São Paulo (USP), Hospital das Clínicas de Ribeirão Preto (HCRP), HC Criança, Ribeirão Preto, SP, Brazil. Electronic address: mppenteado@usp.br., Grandi C; Sociedade Argentina de Pediatria, Comissão de Pesquisa, Buenos Aires, Argentina., Rodrigues LDS; Universidade Federal do Maranhão, Departamento de Saúde Pública, São Luís, MA, Brazil., Cardoso VC; Universidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Puericultura e Pediatria, Ribeirão Preto, SP, Brazil. |
| المصدر: | Jornal de pediatria [J Pediatr (Rio J)] 2024 Jul-Aug; Vol. 100 (4), pp. 377-383. Date of Electronic Publication: 2024 Feb 09. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Editora Ltda Country of Publication: Brazil NLM ID: 2985188R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4782 (Electronic) Linking ISSN: 00217557 NLM ISO Abbreviation: J Pediatr (Rio J) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Rio de Janeiro, Brazil : Elsevier Editora Ltda Original Publication: Rio de Janeiro. |
| مواضيع طبية MeSH: | Placenta*/anatomy & histology , Birth Weight*/physiology , Anthropometry*/methods, Humans ; Female ; Infant, Newborn ; Pregnancy ; Cross-Sectional Studies ; Adult ; Male ; Infant, Small for Gestational Age ; Phenotype ; Brazil ; Nutritional Status/physiology ; Young Adult ; Birth Cohort ; Gestational Age |
| مستخلص: | Objective: To study the association between placental efficiency with anthropometry and nutritional phenotypes in full-term newborns from a birth cohort. Method: This was a secondary cross-sectional analysis of data obtained in a cohort study (Brazilian RibeirãoPreto and São Luís Birth Cohort Studies - BRISA), whose deliveries were performed between 2010 and 2011. Standardized questionnaires were applied to mothers, and placentas and newborns were evaluated shortly after delivery. Placental efficiency was assessed using the ratio between birth weight and placental weight (BW/PW ratio); values below the lower quartile (25th percentile for gestational age) were considered to have low placental efficiency. Newborn phenotypes were small and large for gestational age, stunted and wasted, evaluated using the INTERGROWTH-21 growth standard. To identify the confounding variables theoretical model was constructed using Directed Acyclic Graphs, and unadjusted and adjusted logistic regression were performed. Placental measurements were obtained blindly from pregnancy and delivery data. Results: 723 mother-placenta-child triads were studied. 3.2 % of newborns were small-for-gestational-age (SGA), 6.5 %large-for-gestational-age (LGA), 5.7 %had stunting, and 0.27 % wasting. A significantly higher risk was found between low placental efficiency and SGA (OR 2.82;95 % CI 1.05-7.57), stunting (OR 2.23; 95 % CI 1.07-4.65), and wasting (OR 8.22; 95 % CI 1.96-34.37). No relationship was found between LGA and placental efficiency. Conclusions: Low placental efficiency was associated with increased risk for small-for-gestational-age, stunting, and wasting. Placental morphometry can provide valuable information on intrauterine conditions and neonatal health, helping to identify newborns at higher risk of future comorbidities. Competing Interests: Conflicts of interest The authors declare no conflicts of interest. (Copyright © 2024 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Birth weight; Phenotype; Placenta; Small-for-gestational-age; Stunting; Wasting |
| تواريخ الأحداث: | Date Created: 20240212 Date Completed: 20240606 Latest Revision: 20240606 |
| رمز التحديث: | 20240607 |
| DOI: | 10.1016/j.jped.2023.11.011 |
| PMID: | 38346677 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-4782 |
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| DOI: | 10.1016/j.jped.2023.11.011 |