دورية أكاديمية
أعرض في EDS

Mitral Annular Calcification as a Potential False-Positive for Cardiac Amyloidosis in 99m Tc-DPD Scintigraphy Accurately Identified by SPECT/CT.

التفاصيل البيبلوغرافية
العنوان: Mitral Annular Calcification as a Potential False-Positive for Cardiac Amyloidosis in 99m Tc-DPD Scintigraphy Accurately Identified by SPECT/CT.
المؤلفون: Nunes ARP; From the Centro Hospitalar Universitário de São João, Porto, Portugal., Alves VM
المصدر: Clinical nuclear medicine [Clin Nucl Med] 2024 Apr 01; Vol. 49 (4), pp. e179-e181. Date of Electronic Publication: 2024 Feb 09.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Country of Publication: United States NLM ID: 7611109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-0229 (Electronic) Linking ISSN: 03639762 NLM ISO Abbreviation: Clin Nucl Med Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Philadelphia, Lippincott.
مواضيع طبية MeSH: Calcinosis* , Amyloidosis*/diagnostic imaging, Humans ; Mitral Valve/diagnostic imaging ; Single Photon Emission Computed Tomography Computed Tomography ; Tomography, Emission-Computed, Single-Photon ; Radionuclide Imaging
مستخلص: Abstract: 99m Tc-PYP/DPD/HDMP cardiac scintigraphy has a pivotal role in the diagnosis of ATTR cardiac amyloidosis. The combined findings of a Perugini visual score of 2 or 3 in the scan and the absence of monoclonal proteins in blood and urine are highly specific for the diagnosis of ATTR cardiac amyloidosis without a tissue biopsy. We report a case of mitral annular and valve calcification accurately identified in the SPECT/CT, but which could be misinterpreted as ATTR cardiac amyloidosis if only acquiring planar and SPECT images.
Competing Interests: Conflicts of interest and sources of funding: none declared.
(Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
References: Kittleson MM, Maurer MS, Ambardekar AV, et al. Cardiac amyloidosis: evolving diagnosis and management: a scientific statement from the American Heart Association. Circulation . 2020;142:e7–e22.
Ruberg FL, Grogan M, Hanna M, et al. Transthyretin amyloid cardiomyopathy: JACC state-of-the-art review. J Am Coll Cardiol . 2019;73:2872–2891.
Falk RH, Alexander KM, Liao R, et al. AL (light-chain) cardiac amyloidosis: a review of diagnosis and therapy. J Am Coll Cardiol . 2016;68:1323–1341.
Kittleson MM, Panjrath GS, Amancherla K, et al. 2023 ACC expert consensus decision pathway on management of heart failure with preserved ejection fraction: a report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol . 2023;81:1835–1878.
Hanna M, Ruberg FL, Maurer MS, et al. Cardiac scintigraphy with technetium-99m-labeled bone-seeking tracers for suspected amyloidosis: JACC review topic of the week. J Am Coll Cardiol . 2020;75:2851–2862.
Dorbala S, Ando Y, Bokhari S, et al. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: part 1 of 2-evidence base and standardized methods of imaging. J Nucl Cardiol . 2019;26:2065–2123.
Delaney FT, Dempsey P, Welaratne I, et al. Incidental cardiac uptake in bone scintigraphy: increased importance and association with cardiac amyloidosis. BJR Case Rep . 2021;7:20200161.
Wale DJ, Wong KK, Savas H, et al. Extraosseous findings on bone scintigraphy using fusion SPECT/CT and correlative imaging. AJR Am J Roentgenol . 2015;205:160–172.
Paeng JC, Choi JY. Nuclear imaging for cardiac amyloidosis: bone scan, SPECT/CT, and amyloid-targeting PET. Nucl Med Mol Imaging . 2021;55:61–70.
تواريخ الأحداث: Date Created: 20240213 Date Completed: 20240304 Latest Revision: 20240304
رمز التحديث: 20240304
DOI: 10.1097/RLU.0000000000005086
PMID: 38350093
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-0229
DOI:10.1097/RLU.0000000000005086