دورية أكاديمية

Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV.

التفاصيل البيبلوغرافية
العنوان: Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV.
المؤلفون: Bridget Spelke M; Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA. bspelke@email.unc.edu.; University of North Carolina - Global Projects Zambia, 348 Independence Ave, Lusaka, Zambia, 10101. bspelke@email.unc.edu., Okumu E; Social and Behavioral Science Core, Center for AIDS Research, University of North Carolina, Chapel Hill, USA., Perry NR; Social and Behavioral Science Core, Center for AIDS Research, University of North Carolina, Chapel Hill, USA., Blette BS; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, USA., Paul R; Department of Psychiatry, University of Zambia School of Medicine, Lusaka, Zambia., Schiller CE; Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, USA., Ncheka JM; Department of Psychiatry, University of Zambia School of Medicine, Lusaka, Zambia., Kasaro MP; University of North Carolina - Global Projects Zambia, 348 Independence Ave, Lusaka, Zambia, 10101., Price JT; Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA.; University of North Carolina - Global Projects Zambia, 348 Independence Ave, Lusaka, Zambia, 10101., Meltzer-Brody S; Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, USA., Stringer JSA; Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA.; University of North Carolina - Global Projects Zambia, 348 Independence Ave, Lusaka, Zambia, 10101., Stringer EM; Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA.; University of North Carolina - Global Projects Zambia, 348 Independence Ave, Lusaka, Zambia, 10101.
المصدر: AIDS and behavior [AIDS Behav] 2024 Apr; Vol. 28 (4), pp. 1123-1136. Date of Electronic Publication: 2024 Feb 14.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9712133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-3254 (Electronic) Linking ISSN: 10907165 NLM ISO Abbreviation: AIDS Behav Subsets: MEDLINE
أسماء مطبوعة: Publication: 2005- : New York, NY : Springer Science + Business Media
Original Publication: New York, NY : Plenum Press, 1997-
مواضيع طبية MeSH: Depression, Postpartum*/epidemiology , Depressive Disorder*/complications , HIV Infections*/complications , HIV Infections*/epidemiology , HIV Infections*/psychology, Adult ; Female ; Humans ; Pregnancy ; Depression/therapy ; Postpartum Period ; Treatment Outcome ; Randomized Controlled Trials as Topic
مستخلص: Postpartum depression (PPD) affects nearly 20% of postpartum women in Sub-Saharan Africa (SSA), where HIV prevalence is high. Depression is associated with worse HIV outcomes in non-pregnant adults and mental health disorders may worsen HIV outcomes for postpartum women and their infants. PPD is effectively treated with psychosocial or pharmacologic interventions; however, few studies have evaluated the acceptability of treatment modalities in SSA. We analyzed interviews with 23 postpartum women with HIV to assess the acceptability of two depression treatments provided in the context of a randomized trial. Most participants expressed acceptability of treatment randomization and study visit procedures. Participants shared perceptions of high treatment efficacy of their assigned intervention. They reported ongoing HIV and mental health stigma in their communities and emphasized the importance of social support from clinic staff. Our findings suggest a full-scale trial of PPD treatment will be acceptable among women with HIV in Zambia.
(© 2024. The Author(s).)
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معلومات مُعتمدة: K01 TW012426 United States TW FIC NIH HHS; R21 MH115806 United States MH NIMH NIH HHS; 1R21MH115806 United States MH NIMH NIH HHS; K01TW012426 United States TW FIC NIH HHS
فهرسة مساهمة: Keywords: Antidepressant medication; Depression; HIV; Interpersonal therapy; Low resource setting; Zambia
تواريخ الأحداث: Date Created: 20240214 Date Completed: 20240318 Latest Revision: 20240607
رمز التحديث: 20240607
مُعرف محوري في PubMed: PMC10940463
DOI: 10.1007/s10461-023-04264-0
PMID: 38353877
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-3254
DOI:10.1007/s10461-023-04264-0