دورية أكاديمية
Project NextGen: Developing the Next Generation of COVID-19 Vaccines and Therapeutics to Respond to the Present and Prepare for the Future.
العنوان: | Project NextGen: Developing the Next Generation of COVID-19 Vaccines and Therapeutics to Respond to the Present and Prepare for the Future. |
---|---|
المؤلفون: | Hofmeyer KA; Biomedical Advanced Research and Development Authority, Administration for Strategic Preparedness and Response, U.S. Department of Health and Human Services, Washington, DC, USA., Ventura CL; Biomedical Advanced Research and Development Authority, Administration for Strategic Preparedness and Response, U.S. Department of Health and Human Services, Washington, DC, USA., Armstrong KL; Biomedical Advanced Research and Development Authority, Administration for Strategic Preparedness and Response, U.S. Department of Health and Human Services, Washington, DC, USA., Houchens CR; Biomedical Advanced Research and Development Authority, Administration for Strategic Preparedness and Response, U.S. Department of Health and Human Services, Washington, DC, USA., Patel S; Biomedical Advanced Research and Development Authority, Administration for Strategic Preparedness and Response, U.S. Department of Health and Human Services, Washington, DC, USA., Disbrow GL; Biomedical Advanced Research and Development Authority, Administration for Strategic Preparedness and Response, U.S. Department of Health and Human Services, Washington, DC, USA., Johnson RA; Biomedical Advanced Research and Development Authority, Administration for Strategic Preparedness and Response, U.S. Department of Health and Human Services, Washington, DC, USA. |
مؤلفون مشاركون: | Project NextGen Line of Effort Leads |
المصدر: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2024 Jul 19; Vol. 79 (1), pp. 115-121. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Jan. 2011- : Oxford : Oxford University Press Original Publication: Chicago, IL : The University of Chicago Press, c1992- |
مواضيع طبية MeSH: | COVID-19 Vaccines* , COVID-19*/prevention & control , COVID-19*/epidemiology , SARS-CoV-2*/immunology , Public-Private Sector Partnerships*, Humans ; United States ; Vaccine Development ; COVID-19 Drug Treatment ; Antiviral Agents/therapeutic use ; Drug Development/trends ; Pandemics/prevention & control |
مستخلص: | Coronavirus disease 2019 (COVID-19) epidemiology and product landscapes have changed considerably since onset of the pandemic. Safe and effective vaccines and therapeutics are available, but the continual emergence of severe acute respiratory syndrome coronavirus 2 variants introduce limitations in our ability to prevent and treat disease. Project NextGen is a collaboration between the Biomedical Advanced Research and Development Authority, part of the Administration for Strategic Preparedness and Response, and the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, that is leveraging public-private partnerships to address gaps in the nation's COVID-19 vaccine and therapeutic capabilities. Targeted investments will advance promising next-generation candidates through the most difficult phases of clinical development to encourage further private sector interest for later stage development and commercial availability. New commercial vaccines and therapeutics that are more durable and effective across variants will improve our fight against COVID-19 and transform our response to future threats. Competing Interests: Potential conflicts of interest . The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. (© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America.) |
References: | NPJ Vaccines. 2023 Apr 12;8(1):53. (PMID: 37045860) Contemp Clin Trials. 2022 May;116:106740. (PMID: 35364292) N Engl J Med. 2023 Aug 31;389(9):773-775. (PMID: 37494477) BMJ. 2023 Mar 1;380:e073747. (PMID: 36858453) Immunol Rev. 2022 Sep;310(1):27-46. (PMID: 35733376) Vaccine. 2023 Oct 6;41(42):6221-6226. (PMID: 37666694) PLoS Pathog. 2022 Sep 30;18(9):e1010876. (PMID: 36178969) Lancet Infect Dis. 2022 Sep;22(9):1293-1302. (PMID: 35753318) Lancet Infect Dis. 2023 Jul;23(7):806-815. (PMID: 36933565) Ann Intern Med. 2023 Apr;176(4):496-504. (PMID: 37011399) Nat Rev Microbiol. 2023 Feb;21(2):112-124. (PMID: 36307535) Int J Biol Macromol. 2023 Feb 28;229:70-80. (PMID: 36586649) Open Forum Infect Dis. 2022 Mar 10;9(5):ofac124. (PMID: 35493113) Expert Rev Vaccines. 2023 Jan-Dec;22(1):422-439. (PMID: 37161869) Hum Vaccin Immunother. 2022 Nov 30;18(6):2129930. (PMID: 36302122) BioDrugs. 2020 Jun;34(3):273-293. (PMID: 32157600) Int J Infect Dis. 2023 Sep;134:228-238. (PMID: 37400053) Clin Infect Dis. 2022 Aug 24;75(1):e630-e644. (PMID: 35179197) Clin Ther. 2023 May;45(5):390-399.e4. (PMID: 37032225) N Engl J Med. 2020 Oct 29;383(18):1701-1703. (PMID: 32846056) J Infect Dis. 2023 Jun 15;227(12):1433-1441. (PMID: 35876700) Am J Kidney Dis. 2022 Apr;79(4):480-482. (PMID: 35032591) Infect Dis Ther. 2023 Feb;12(2):367-387. (PMID: 36622633) Clin Infect Dis. 2023 Apr 17;76(8):1391-1399. (PMID: 36482505) Cells. 2020 Oct 22;9(11):. (PMID: 33105869) |
فهرسة مساهمة: | Investigator: AC Bandremer; JH Beigel; TT Belski; RO Donis; L Jayashankar; RA Koup; GR Kovacs; MA Link; KA Martins; RM Mason; SM Stronsky; DN Wolfe Keywords: COVID-19; COVID-19 therapeutics; COVID-19 vaccines; medical countermeasures; pandemic preparedness |
المشرفين على المادة: | 0 (COVID-19 Vaccines) 0 (Antiviral Agents) |
SCR Organism: | SARS-CoV-2 variants |
تواريخ الأحداث: | Date Created: 20240215 Date Completed: 20240719 Latest Revision: 20240721 |
رمز التحديث: | 20240721 |
مُعرف محوري في PubMed: | PMC11259220 |
DOI: | 10.1093/cid/ciae073 |
PMID: | 38356144 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1537-6591 |
---|---|
DOI: | 10.1093/cid/ciae073 |