دورية أكاديمية
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Microbiota-gut-brain axis and its therapeutic applications in neurodegenerative diseases.

التفاصيل البيبلوغرافية
العنوان: Microbiota-gut-brain axis and its therapeutic applications in neurodegenerative diseases.
المؤلفون: Loh JS; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor, Malaysia., Mak WQ; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor, Malaysia., Tan LKS; School of Pharmacy, Faculty of Health & Medical Sciences, Taylor's University, 1, Jalan Taylors, Subang Jaya, 47500, Selangor, Malaysia.; Digital Health & Medical Advancements, Taylor's University, 1, Jalan Taylors, Subang Jaya, 47500, Selangor, Malaysia., Ng CX; School of Biosciences, Faculty of Health & Medical Sciences, Taylor's University, 1, Jalan Taylors, Subang Jaya, 47500, Selangor, Malaysia., Chan HH; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor, Malaysia., Yeow SH; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK., Foo JB; School of Pharmacy, Faculty of Health & Medical Sciences, Taylor's University, 1, Jalan Taylors, Subang Jaya, 47500, Selangor, Malaysia.; Digital Health & Medical Advancements, Taylor's University, 1, Jalan Taylors, Subang Jaya, 47500, Selangor, Malaysia., Ong YS; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor, Malaysia., How CW; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor, Malaysia. how.cheewun@monash.edu., Khaw KY; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor, Malaysia. Khaw.KooiYeong@monash.edu.
المصدر: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2024 Feb 16; Vol. 9 (1), pp. 37. Date of Electronic Publication: 2024 Feb 16.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : Nature Publishing Group, [2016]-
مواضيع طبية MeSH: Neurodegenerative Diseases*/therapy , Neurodegenerative Diseases*/metabolism , Probiotics*/therapeutic use, Humans ; Brain/metabolism ; Brain-Gut Axis ; Prebiotics
مستخلص: The human gastrointestinal tract is populated with a diverse microbial community. The vast genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every aspect of human biology, including health maintenance, development, aging, and disease. The advent of new sequencing technologies and culture-independent methods has allowed researchers to move beyond correlative studies toward mechanistic explorations to shed light on microbiome-host interactions. Evidence has unveiled the bidirectional communication between the gut microbiome and the central nervous system, referred to as the "microbiota-gut-brain axis". The microbiota-gut-brain axis represents an important regulator of glial functions, making it an actionable target to ameliorate the development and progression of neurodegenerative diseases. In this review, we discuss the mechanisms of the microbiota-gut-brain axis in neurodegenerative diseases. As the gut microbiome provides essential cues to microglia, astrocytes, and oligodendrocytes, we examine the communications between gut microbiota and these glial cells during healthy states and neurodegenerative diseases. Subsequently, we discuss the mechanisms of the microbiota-gut-brain axis in neurodegenerative diseases using a metabolite-centric approach, while also examining the role of gut microbiota-related neurotransmitters and gut hormones. Next, we examine the potential of targeting the intestinal barrier, blood-brain barrier, meninges, and peripheral immune system to counteract glial dysfunction in neurodegeneration. Finally, we conclude by assessing the pre-clinical and clinical evidence of probiotics, prebiotics, and fecal microbiota transplantation in neurodegenerative diseases. A thorough comprehension of the microbiota-gut-brain axis will foster the development of effective therapeutic interventions for the management of neurodegenerative diseases.
(© 2024. The Author(s).)
References: Glia. 2020 Feb;68(2):407-421. (PMID: 31596526)
Sci Rep. 2018 Feb 16;8(1):3176. (PMID: 29453346)
Cell Rep. 2022 Feb 15;38(7):110358. (PMID: 35172141)
Nat Genet. 2022 Apr;54(4):412-436. (PMID: 35379992)
Nat Commun. 2020 Sep 8;11(1):4457. (PMID: 32901017)
Nature. 2021 Jul;595(7867):409-414. (PMID: 34194038)
NPJ Parkinsons Dis. 2023 Jan 27;9(1):11. (PMID: 36707543)
CNS Neurosci Ther. 2023 Aug 1;:. (PMID: 37528534)
Science. 2015 Aug 28;349(6251):989-93. (PMID: 26160380)
Cell Host Microbe. 2022 Jul 13;30(7):944-960.e8. (PMID: 35654045)
Pharmaceuticals (Basel). 2021 Jan 11;14(1):. (PMID: 33440796)
Brain Res. 2003 Feb 21;964(1):107-15. (PMID: 12573518)
Cell Rep Med. 2020 Nov 17;1(8):100138. (PMID: 33294859)
Cell Res. 2019 Oct;29(10):787-803. (PMID: 31488882)
Nature. 2023 May;617(7961):581-591. (PMID: 37165188)
Nat Metab. 2022 Apr;4(4):416-423. (PMID: 35338368)
Acta Neuropathol. 2016 Mar;131(3):347-63. (PMID: 26711460)
AMB Express. 2020 Apr 24;10(1):80. (PMID: 32333225)
Microbiome. 2023 Jan 31;11(1):17. (PMID: 36721179)
Neuron. 2023 Jan 4;111(1):15-29.e8. (PMID: 36368316)
Aging (Albany NY). 2020 Sep 9;12(17):16690-16708. (PMID: 32903216)
Front Physiol. 2020 Sep 23;11:973. (PMID: 33071801)
Trends Mol Med. 2023 Oct;29(10):802-816. (PMID: 37591764)
Nat Med. 2022 Nov;28(11):2333-2343. (PMID: 36216932)
Redox Biol. 2023 Jun;62:102690. (PMID: 37018970)
Neurology. 2020 Feb 25;94(8):e811-e819. (PMID: 31796528)
Neurology. 2020 Nov 10;95(19):e2658-e2665. (PMID: 32913021)
Brain Behav Immun. 2022 Nov;106:76-88. (PMID: 35961580)
J Exp Med. 2019 Jan 7;216(1):41-59. (PMID: 30385457)
Nat Ecol Evol. 2023 Jan;7(1):127-142. (PMID: 36604549)
Brain. 2016 Apr;139(Pt 4):1252-64. (PMID: 26984188)
Cell Host Microbe. 2018 Jun 13;23(6):716-724. (PMID: 29902437)
Nature. 2023 Oct;622(7981):120-129. (PMID: 37674083)
Nature. 2019 Apr;568(7751):187-192. (PMID: 30944478)
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16050-5. (PMID: 21876150)
Transl Psychiatry. 2021 May 27;11(1):328. (PMID: 34045460)
Diabetes Care. 2020 Sep;43(9):2169-2175. (PMID: 32611610)
Cell Mol Gastroenterol Hepatol. 2021;11(5):1463-1482. (PMID: 33610769)
Cell Metab. 2020 Apr 7;31(4):837-851.e10. (PMID: 32213346)
Neuron. 2011 Oct 20;72(2):257-68. (PMID: 21944779)
Nature. 2017 Nov 30;551(7682):585-589. (PMID: 29143823)
Sci Adv. 2023 Apr 21;9(16):eabq0651. (PMID: 37083530)
Mol Psychiatry. 2023 Jul 7;:. (PMID: 37419974)
Signal Transduct Target Ther. 2019 Aug 23;4:29. (PMID: 31637009)
Nat Immunol. 2022 Dec;23(12):1714-1725. (PMID: 36411380)
JAMA. 2009 Dec 16;302(23):2565-72. (PMID: 20009056)
Mucosal Immunol. 2021 Nov;14(6):1235-1246. (PMID: 34075183)
J Neurol Neurosurg Psychiatry. 2020 Dec;91(12):1329-1338. (PMID: 32928939)
Ageing Res Rev. 2023 Apr;86:101865. (PMID: 36716975)
Transl Psychiatry. 2022 Feb 24;12(1):79. (PMID: 35210396)
Mol Neurodegener. 2022 Nov 23;17(1):75. (PMID: 36419137)
Nat Med. 2020 May;26(5):769-780. (PMID: 32284590)
J Nutr Biochem. 2018 Sep;59:142-152. (PMID: 30005919)
Nature. 2020 Dec;588(7837):303-307. (PMID: 33239790)
Nature. 2023 Mar;615(7953):668-677. (PMID: 36890231)
NPJ Parkinsons Dis. 2022 Jun 1;8(1):65. (PMID: 35650236)
Immunity. 2023 Apr 11;56(4):829-846.e8. (PMID: 36822206)
Cell Stem Cell. 2023 Aug 3;30(8):1043-1053.e6. (PMID: 37541210)
Mol Neurodegener. 2023 Feb 1;18(1):9. (PMID: 36721148)
Cell Biosci. 2023 Jun 3;13(1):101. (PMID: 37270503)
Sci Rep. 2023 Feb 16;13(1):2819. (PMID: 36797287)
Genes Immun. 2020 Nov;21(5):288-300. (PMID: 33011744)
EBioMedicine. 2022 Mar;77:103908. (PMID: 35255456)
Microbiol Spectr. 2022 Apr 27;10(2):e0009022. (PMID: 35289669)
Nat Rev Neurosci. 2023 Sep;24(9):523-539. (PMID: 37495761)
Neurology. 2003 May 13;60(9):1495-500. (PMID: 12743238)
Gut. 2017 Apr;66(4):569-580. (PMID: 28087657)
Mol Neurobiol. 2018 Dec;55(12):9139-9155. (PMID: 29651747)
NPJ Parkinsons Dis. 2023 Jun 24;9(1):98. (PMID: 37355689)
N Engl J Med. 2020 Sep 3;383(10):919-930. (PMID: 32877582)
Sci Rep. 2021 Mar 23;11(1):6677. (PMID: 33758296)
Biochim Biophys Acta. 2013 May;1832(5):650-9. (PMID: 23402925)
Nat Rev Neurosci. 2014 Dec;15(12):771-85. (PMID: 25387473)
Int J Biol Macromol. 2022 Sep 30;217:677-688. (PMID: 35853505)
Nat Rev Endocrinol. 2021 Sep;17(9):549-559. (PMID: 34262156)
Brain Behav Immun. 2021 Feb;92:102-114. (PMID: 33242652)
Sci Transl Med. 2014 Nov 19;6(263):263ra158. (PMID: 25411471)
Int J Mol Sci. 2023 Apr 01;24(7):. (PMID: 37047602)
Tissue Barriers. 2023 Jan 2;11(1):2073175. (PMID: 35596559)
Gastroenterology. 2021 Jan;160(1):145-157.e8. (PMID: 32681922)
Microbiome. 2021 Jan 31;9(1):34. (PMID: 33517890)
J Agric Food Chem. 2020 Jul 8;68(27):7152-7161. (PMID: 32583667)
Nat Metab. 2023 Jun;5(6):968-980. (PMID: 37217759)
Gut Microbes. 2020;11(1):1-20. (PMID: 31116628)
Nat Cell Biol. 2023 Jul;25(7):963-974. (PMID: 37231161)
Parkinsonism Relat Disord. 2016 Nov;32:66-72. (PMID: 27591074)
Trends Microbiol. 2022 Aug;30(8):749-760. (PMID: 35144890)
J Neurochem. 2008 Sep;106(5):2119-30. (PMID: 18636984)
Nat Rev Neurosci. 2020 Mar;21(3):121-138. (PMID: 32042146)
Brain. 2023 Aug 1;146(8):3117-3132. (PMID: 36864664)
Cell Host Microbe. 2021 Dec 8;29(12):1802-1814.e5. (PMID: 34847370)
Muscle Nerve. 2022 Aug;66(2):136-141. (PMID: 35508892)
Cell. 2017 Jun 15;169(7):1276-1290.e17. (PMID: 28602351)
Brain Behav Immun. 2018 May;70:48-60. (PMID: 29471030)
Mol Neurodegener. 2021 Jan 23;16(1):4. (PMID: 33485385)
Aging Dis. 2023 Dec 1;14(6):2193-2214. (PMID: 37199590)
Nature. 2020 May;581(7806):71-76. (PMID: 32376954)
Cell Res. 2020 Jun;30(6):492-506. (PMID: 32433595)
Sci Adv. 2020 Jul 29;6(31):eaba0466. (PMID: 32832679)
Cell Mol Immunol. 2021 May;18(5):1161-1171. (PMID: 33850311)
Alzheimers Dement. 2019 Jan;15(1):76-92. (PMID: 30337151)
Mol Neurobiol. 2023 Sep;60(9):5137-5154. (PMID: 37266763)
JAMA Netw Open. 2023 Feb 1;6(2):e2255758. (PMID: 36780159)
Nat Rev Neurol. 2023 Jul;19(7):395-409. (PMID: 37308616)
Nat Neurosci. 2023 Jul;26(7):1208-1217. (PMID: 37365313)
Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):. (PMID: 34187889)
Nat Biotechnol. 2024 Feb;42(2):328-338. (PMID: 37106038)
Cell Host Microbe. 2020 Mar 11;27(3):389-404.e6. (PMID: 32004499)
Neurochem Int. 2023 Jan;162:105459. (PMID: 36460238)
Nat Rev Cardiol. 2023 Feb;20(2):77-89. (PMID: 36064969)
Nutr Neurosci. 2022 Jul;25(7):1374-1391. (PMID: 33345721)
Immunity. 2018 Aug 21;49(2):353-362.e5. (PMID: 30119997)
J Cell Physiol. 2020 Nov;235(11):8558-8570. (PMID: 32329059)
Clin Chim Acta. 2020 Feb;501:165-173. (PMID: 31726035)
Trends Cogn Sci. 2019 Mar;23(3):213-234. (PMID: 30711326)
Nat Microbiol. 2021 Jul;6(7):865-873. (PMID: 33972766)
Neuron. 2018 Dec 19;100(6):1322-1336.e7. (PMID: 30392797)
Nat Neurosci. 2018 Mar;21(3):329-340. (PMID: 29463850)
Nat Med. 2014 Nov;20(11):1254-62. (PMID: 25326800)
J Clin Diagn Res. 2017 Aug;11(8):KC01-KC05. (PMID: 28969160)
Sci Rep. 2022 Mar 15;12(1):4414. (PMID: 35292710)
Nat Med. 2022 Sep;28(9):1913-1923. (PMID: 36109637)
Brain Behav Immun. 2021 Jan;91:324-338. (PMID: 33039664)
Nutr Neurosci. 2022 Feb;25(2):321-335. (PMID: 32297553)
Nat Metab. 2022 Nov;4(11):1560-1572. (PMID: 36357685)
Neuroimage. 2016 Jan 15;125:988-995. (PMID: 26577887)
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):979-84. (PMID: 17210919)
Mov Disord. 2022 Aug;37(8):1634-1643. (PMID: 35607987)
Microbiome. 2022 Mar 11;10(1):47. (PMID: 35272713)
Front Microbiol. 2016 Sep 20;7:1479. (PMID: 27703453)
Cell. 2019 May 30;177(6):1600-1618.e17. (PMID: 31150625)
Nat Commun. 2022 Dec 6;13(1):7128. (PMID: 36473852)
Trends Endocrinol Metab. 2019 Nov;30(11):844-859. (PMID: 31445747)
Front Aging Neurosci. 2023 Jan 18;14:986127. (PMID: 36742204)
Sci Data. 2021 Oct 15;8(1):270. (PMID: 34654824)
Mol Psychiatry. 2022 Jul;27(7):2940-2949. (PMID: 35444256)
Nutrients. 2021 Jun 19;13(6):. (PMID: 34205336)
Nat Metab. 2019 May;1(5):532-545. (PMID: 31656947)
Cell Host Microbe. 2015 Nov 11;18(5):582-92. (PMID: 26526499)
Sci Transl Med. 2023 Jun 14;15(700):eabo2984. (PMID: 37315112)
Sci Transl Med. 2020 Feb 5;12(529):. (PMID: 32024798)
Mol Nutr Food Res. 2020 Jan;64(2):e1900636. (PMID: 31835282)
Mol Ther. 2018 Feb 7;26(2):550-567. (PMID: 29273501)
Brain. 2020 Mar 1;143(3):1010-1026. (PMID: 32179883)
Biomed Pharmacother. 2022 Jun;150:112933. (PMID: 35413600)
Cell Metab. 2021 May 4;33(5):923-938.e6. (PMID: 33651981)
Nat Commun. 2023 Sep 6;14(1):5471. (PMID: 37673907)
Brain Behav Immun. 2022 Oct;105:1-14. (PMID: 35688338)
Front Cell Infect Microbiol. 2023 Apr 11;13:1103189. (PMID: 37113132)
Prog Neurobiol. 2022 Sep;216:102306. (PMID: 35714860)
Gut Microbes. 2020 Nov 9;12(1):1802866. (PMID: 32835590)
Front Aging Neurosci. 2016 Nov 10;8:256. (PMID: 27891089)
Neurosci Lett. 2021 Jan 10;741:135493. (PMID: 33181233)
Clin Nutr. 2019 Dec;38(6):2569-2575. (PMID: 30642737)
Nat Rev Microbiol. 2022 Jun;20(6):365-380. (PMID: 34992261)
Nat Med. 2022 Sep;28(9):1902-1912. (PMID: 36109636)
Biosci Biotechnol Biochem. 2019 Nov;83(11):2144-2152. (PMID: 31327302)
Nat Rev Immunol. 2023 Nov;23(11):735-748. (PMID: 37138015)
Pharmacol Res. 2020 Jul;157:104784. (PMID: 32305492)
Nature. 2020 May;581(7809):475-479. (PMID: 32461639)
Nat Rev Neurosci. 2020 Dec;21(12):717-731. (PMID: 33067567)
Cell. 2023 Jan 19;186(2):243-278. (PMID: 36599349)
J Adv Res. 2023 Mar;45:117-125. (PMID: 35618633)
Sci Adv. 2021 Oct 22;7(43):eabg4980. (PMID: 34669475)
Exp Neurol. 2022 Jul;353:114081. (PMID: 35405119)
Toxicol Appl Pharmacol. 2022 Jan 15;435:115853. (PMID: 34973289)
Brain Pathol. 2020 Nov;30(6):1159-1177. (PMID: 33073887)
Nat Neurosci. 2018 Jun;21(6):779-786. (PMID: 29735982)
Brain. 2020 May 1;143(5):1588-1602. (PMID: 32380523)
Nutrients. 2021 Mar 29;13(4):. (PMID: 33805289)
Nat Rev Immunol. 2021 Sep;21(9):548-569. (PMID: 33833439)
Nat Microbiol. 2022 Sep;7(9):1390-1403. (PMID: 35982311)
Nat Rev Genet. 2023 Sep;24(9):642-658. (PMID: 37024676)
Nature. 2017 Sep 28;549(7673):523-527. (PMID: 28959956)
Cell. 2023 Feb 16;186(4):693-714. (PMID: 36803602)
J Biomed Res. 2022 Dec 28;37(2):125-137. (PMID: 36814376)
Eur J Nutr. 2023 Oct;62(7):2991-3007. (PMID: 37460822)
Cell Host Microbe. 2023 Jan 11;31(1):33-44.e5. (PMID: 36495868)
Aging (Albany NY). 2020 Jan 6;12(1):628-649. (PMID: 31907339)
Nat Neurosci. 2023 Jul;26(7):1196-1207. (PMID: 37291336)
Mol Neurodegener. 2022 Jun 17;17(1):43. (PMID: 35715821)
Lancet Neurol. 2012 Apr;11(4):323-30. (PMID: 22406228)
Int J Biol Macromol. 2020 Dec 1;164:994-1005. (PMID: 32710966)
Nat Neurosci. 2022 Aug;25(8):1020-1033. (PMID: 35915180)
Cell Host Microbe. 2022 Feb 9;30(2):183-199.e10. (PMID: 35085504)
Sci Rep. 2020 Aug 3;10(1):12998. (PMID: 32747678)
Nat Rev Gastroenterol Hepatol. 2022 Oct;19(10):625-637. (PMID: 35641786)
NPJ Parkinsons Dis. 2022 May 24;8(1):62. (PMID: 35610236)
Nat Neurosci. 2023 Sep;26(9):1541-1554. (PMID: 37563296)
Brain. 2023 Dec 1;146(12):4916-4934. (PMID: 37849234)
Nat Aging. 2023 Apr;3(4):436-449. (PMID: 37117794)
Cell Host Microbe. 2015 May 13;17(5):690-703. (PMID: 25974306)
Lancet Neurol. 2019 Feb;18(2):211-220. (PMID: 30663610)
Cell Rep. 2021 May 25;35(8):109163. (PMID: 34038733)
Gut. 2023 Sep;72(9):1642-1650. (PMID: 37339849)
Brain Commun. 2022 Aug 12;4(4):fcac205. (PMID: 36035436)
Nat Med. 2016 Jul 7;22(7):713-22. (PMID: 27387886)
Int J Mol Sci. 2023 Mar 20;24(6):. (PMID: 36982969)
NPJ Biofilms Microbiomes. 2023 Aug 14;9(1):56. (PMID: 37580334)
Mol Nutr Food Res. 2024 Jan;68(2):e2300601. (PMID: 38031265)
Cell. 2022 Jun 23;185(13):2213-2233.e25. (PMID: 35750033)
Nature. 2020 Jan;577(7790):410-415. (PMID: 31875848)
Nature. 2019 Oct;574(7779):543-548. (PMID: 31645720)
Brain Behav Immun. 2021 May;94:299-307. (PMID: 33486003)
Transl Psychiatry. 2019 Aug 5;9(1):189. (PMID: 31383855)
JAMA Netw Open. 2022 Feb 1;5(2):e2146324. (PMID: 35103790)
Nutrition. 2021 Mar;83:111090. (PMID: 33418492)
Nat Rev Neurosci. 2023 Apr;24(4):233-251. (PMID: 36823458)
EMBO J. 2019 Feb 15;38(4):. (PMID: 30617086)
Nat Biomed Eng. 2023 Jan;7(1):38-55. (PMID: 36550307)
Mol Neurobiol. 2016 Mar;53(2):810-817. (PMID: 25502462)
Nat Rev Gastroenterol Hepatol. 2019 Aug;16(8):461-478. (PMID: 31123355)
Gut Microbes. 2021 Jan-Dec;13(1):1996848. (PMID: 34812107)
Nat Commun. 2020 Jul 24;11(1):3755. (PMID: 32709874)
J Gerontol A Biol Sci Med Sci. 2023 Mar 30;78(4):645-652. (PMID: 36441007)
Nat Commun. 2021 Apr 20;12(1):2289. (PMID: 33879784)
Nat Commun. 2020 Mar 13;11(1):1386. (PMID: 32170061)
Nat Rev Gastroenterol Hepatol. 2023 Dec;20(12):784-796. (PMID: 37626258)
Nature. 2023 Sep;621(7979):543-549. (PMID: 37558873)
Acta Neuropathol Commun. 2020 Jul 29;8(1):119. (PMID: 32727612)
Nat Rev Drug Discov. 2021 May;20(5):362-383. (PMID: 33649582)
Neurology. 2018 Jul 10;91(2):e139-e142. (PMID: 29898968)
Brain Behav Immun. 2022 May;102:11-22. (PMID: 35143877)
J Biol Chem. 2007 Nov 23;282(47):34479-91. (PMID: 17895242)
Trends Immunol. 2015 Jun;36(6):364-73. (PMID: 26001312)
Nat Commun. 2018 Jul 20;9(1):2872. (PMID: 30030441)
Pharmacol Res. 2023 Jan;187:106614. (PMID: 36538981)
Drugs. 2022 Oct;82(15):1527-1538. (PMID: 36287379)
Gut Microbes. 2023 Jan-Dec;15(1):2168101. (PMID: 36732497)
Glia. 2010 Jan 15;58(2):231-43. (PMID: 19672969)
Mov Disord. 2020 Nov;35(11):2115-2116. (PMID: 32875634)
Nature. 2017 Nov 30;551(7682):648-652. (PMID: 29168502)
Nat Aging. 2023 Mar;3(3):275-296. (PMID: 37118426)
Nat Neurosci. 2023 Mar;26(3):430-446. (PMID: 36732642)
Nat Rev Gastroenterol Hepatol. 2021 Jan;18(1):67-80. (PMID: 32843743)
Exp Neurol. 2008 Aug;212(2):532-7. (PMID: 18577498)
Alzheimers Dement. 2019 Feb;15(2):232-244. (PMID: 30337152)
Nature. 2010 Mar 4;464(7285):59-65. (PMID: 20203603)
Food Funct. 2021 Mar 21;12(6):2591-2604. (PMID: 33629689)
Aging Cell. 2023 Feb;22(2):e13775. (PMID: 36642814)
Neurol Neuroimmunol Neuroinflamm. 2021 Apr 1;8(3):. (PMID: 33795375)
Aging Dis. 2022 Jun 1;13(3):732-752. (PMID: 35656117)
Cell. 2016 Dec 1;167(6):1481-1494.e18. (PMID: 27912058)
Arch Iran Med. 2018 Jul 01;21(7):289-295. (PMID: 30041526)
Gut. 2020 Feb;69(2):283-294. (PMID: 31471351)
Lancet Neurol. 2019 Aug;18(8):748-759. (PMID: 31229470)
J Nutr Biochem. 2019 Jul;69:73-86. (PMID: 31063918)
Neurobiol Aging. 2015 Jan;36(1):228-40. (PMID: 25443293)
J Appl Microbiol. 2012 Aug;113(2):411-7. (PMID: 22612585)
PLoS One. 2013;8(4):e60437. (PMID: 23565247)
J Alzheimers Dis. 2020;77(1):139-147. (PMID: 32623402)
Mol Psychiatry. 2022 Jun;27(6):2659-2673. (PMID: 35361905)
Alzheimers Dement. 2020 Sep;16(9):1312-1329. (PMID: 32543726)
Nature. 2022 Dec;612(7940):417-429. (PMID: 36517712)
J Neuroinflammation. 2022 Sep 28;19(1):236. (PMID: 36171620)
Cell Metab. 2017 Oct 3;26(4):611-619.e6. (PMID: 28978426)
Acta Neuropathol Commun. 2021 Apr 26;9(1):78. (PMID: 33902708)
Transl Psychiatry. 2016 Apr 05;6:e774. (PMID: 27045844)
Cell Host Microbe. 2023 Apr 12;31(4):500-512. (PMID: 37054672)
Brain Sci. 2023 May 12;13(5):. (PMID: 37239262)
Cell Metab. 2022 May 3;34(5):681-701.e10. (PMID: 35508109)
Muscle Nerve. 2021 Jan;63(1):31-39. (PMID: 33063909)
Am J Clin Nutr. 2022 Nov;116(5):1201-1207. (PMID: 37208066)
Nat Rev Neurol. 2018 Mar;14(3):133-150. (PMID: 29377008)
Curr Neurol Neurosci Rep. 2022 Dec;22(12):867-879. (PMID: 36400877)
Science. 2016 May 6;352(6286):712-716. (PMID: 27033548)
Hum Mol Genet. 2021 May 28;30(9):789-810. (PMID: 33791799)
Transl Res. 2019 Feb;204:19-30. (PMID: 30391475)
Neurobiol Aging. 2021 May;101:70-78. (PMID: 33582568)
Nat Biotechnol. 2017 Nov;35(11):1069-1076. (PMID: 28967887)
Neurology. 2021 Feb 2;96(5):e772-e782. (PMID: 33046607)
Mol Aspects Med. 2023 Apr;90:101111. (PMID: 35940942)
Brain Behav. 2021 Aug;11(8):e2226. (PMID: 34105899)
Nat Commun. 2018 Feb 7;9(1):539. (PMID: 29416036)
Nat Rev Immunol. 2019 May;19(5):305-323. (PMID: 30858494)
Front Endocrinol (Lausanne). 2021 Jul 01;12:680494. (PMID: 34276560)
Nature. 2012 May 09;486(7402):222-7. (PMID: 22699611)
Aging Cell. 2023 Apr;22(4):e13787. (PMID: 36734122)
Nature. 2016 Feb 18;530(7590):349-53. (PMID: 26863192)
Nutrients. 2023 Feb 13;15(4):. (PMID: 36839287)
Cell Host Microbe. 2021 Oct 13;29(10):1573-1588.e7. (PMID: 34453895)
Sci Rep. 2018 Jan 19;8(1):1275. (PMID: 29352191)
Cell Metab. 2021 Nov 2;33(11):2260-2276.e7. (PMID: 34731656)
Trends Neurosci. 2020 Dec;43(12):965-979. (PMID: 33127097)
Nat Neurosci. 2023 Jan;26(1):150-162. (PMID: 36482247)
Immunity. 2017 Sep 19;47(3):566-581.e9. (PMID: 28930663)
Nature. 2013 Dec 19;504(7480):451-5. (PMID: 24226773)
Nat Rev Drug Discov. 2020 Sep;19(9):609-633. (PMID: 32709961)
Front Neurol. 2023 Mar 02;14:1104759. (PMID: 36937520)
J Neurosci. 2009 Nov 11;29(45):14057-65. (PMID: 19906954)
Ageing Res Rev. 2019 Nov;55:100944. (PMID: 31430566)
Mol Psychiatry. 2013 Jun;18(6):666-73. (PMID: 22688187)
Cell Stem Cell. 2020 Mar 5;26(3):331-345.e6. (PMID: 31978364)
Nat Commun. 2019 Sep 5;10(1):4007. (PMID: 31488836)
Nat Neurosci. 2018 Oct;21(10):1359-1369. (PMID: 30258234)
Front Cell Infect Microbiol. 2022 Nov 09;12:1022879. (PMID: 36439235)
Mol Neurodegener. 2022 Nov 8;17(1):72. (PMID: 36348357)
NPJ Parkinsons Dis. 2021 Aug 16;7(1):73. (PMID: 34400650)
Nat Rev Microbiol. 2021 Apr;19(4):241-255. (PMID: 33093662)
Aging Cell. 2022 May;21(5):e13599. (PMID: 35349746)
Med Res Rev. 2023 Sep;43(5):1748-1777. (PMID: 37119043)
Nat Immunol. 2023 Mar;24(3):393-407. (PMID: 36759712)
Mol Psychiatry. 2016 Nov;21(11):1613-1623. (PMID: 26830139)
Nutrients. 2022 Nov 18;14(22):. (PMID: 36432569)
Geroscience. 2020 Apr;42(2):613-632. (PMID: 31975051)
J Neuroimmune Pharmacol. 2022 Jun;17(1-2):94-110. (PMID: 35043295)
Int J Mol Sci. 2021 Oct 18;22(20):. (PMID: 34681883)
Nat Rev Mol Cell Biol. 2020 Apr;21(4):183-203. (PMID: 31937935)
Brain. 2020 Oct 1;143(10):3067-3076. (PMID: 33011770)
Aging Cell. 2021 Dec;20(12):e13522. (PMID: 34811872)
Sci Rep. 2017 May 25;7(1):2426. (PMID: 28546539)
Annu Rev Immunol. 2021 Apr 26;39:251-277. (PMID: 33556248)
Nat Commun. 2015 Nov 09;6:8762. (PMID: 26549211)
Brain Behav Immun. 2021 Jan;91:437-450. (PMID: 33157256)
NPJ Parkinsons Dis. 2023 Jun 3;9(1):84. (PMID: 37270646)
Nat Aging. 2021 Aug;1(8):666-676. (PMID: 37117767)
Science. 2019 Jun 14;364(6445):. (PMID: 31196984)
Front Immunol. 2021 Jun 01;12:684430. (PMID: 34140954)
Pharmacol Ther. 2021 Mar;219:107705. (PMID: 33039420)
Neurol Neuroimmunol Neuroinflamm. 2020 Jul 15;7(5):. (PMID: 32669313)
Nat Genet. 2021 Sep;53(9):1276-1282. (PMID: 34493870)
Nat Commun. 2018 May 3;9(1):1784. (PMID: 29725016)
Adv Sci (Weinh). 2022 Dec;9(34):e2201882. (PMID: 36073820)
Brain Behav Immun. 2021 Jul;95:330-343. (PMID: 33839232)
Neuron. 2011 Oct 20;72(2):245-56. (PMID: 21944778)
Neurology. 2020 Nov 10;95(19):e2666-e2674. (PMID: 32913022)
Nat Commun. 2021 Oct 19;12(1):6000. (PMID: 34667167)
Lancet Neurol. 2020 Jul;19(7):582-590. (PMID: 32562683)
Aging Cell. 2019 Dec;18(6):e13037. (PMID: 31560162)
Gastroenterology. 2023 Jun;164(7):1069-1085. (PMID: 36841488)
Brain. 2021 Aug 17;144(7):2047-2059. (PMID: 33704423)
Nat Microbiol. 2022 May;7(5):630-639. (PMID: 35505248)
Front Endocrinol (Lausanne). 2023 Jul 25;14:1169624. (PMID: 37560311)
Nat Metab. 2023 Jul;5(7):1088-1100. (PMID: 37488456)
Nat Commun. 2013;4:1435. (PMID: 23385580)
J Neurosci. 2020 Feb 12;40(7):1453-1482. (PMID: 31896673)
Brain Behav Immun. 2023 Feb;108:98-117. (PMID: 36427810)
NPJ Parkinsons Dis. 2021 Mar 10;7(1):27. (PMID: 33692356)
Amyotroph Lateral Scler Frontotemporal Degener. 2021 May;22(3-4):186-194. (PMID: 33135936)
PLoS One. 2020 Dec 31;15(12):e0244680. (PMID: 33382780)
Ageing Res Rev. 2021 Sep;70:101397. (PMID: 34214643)
Nature. 2018 Oct;562(7728):583-588. (PMID: 30356187)
Mol Brain. 2018 Feb 20;11(1):6. (PMID: 29458391)
J Affect Disord. 2023 May 15;329:493-499. (PMID: 36868384)
Nature. 2022 Dec;612(7941):739-747. (PMID: 36517598)
Trends Microbiol. 2021 Aug;29(8):700-712. (PMID: 33674141)
J Neuroinflammation. 2020 Sep 26;17(1):283. (PMID: 32979923)
Genome Med. 2017 Apr 28;9(1):39. (PMID: 28449715)
Science. 2019 Oct 25;366(6464):494-499. (PMID: 31467190)
Transl Psychiatry. 2023 Jan 21;13(1):17. (PMID: 36670104)
Nature. 2019 Aug;572(7770):474-480. (PMID: 31330533)
Front Pharmacol. 2021 Jan 27;11:586302. (PMID: 33584263)
Nat Rev Neurosci. 2022 Apr;23(4):231-251. (PMID: 35260846)
Nat Commun. 2017 Oct 11;8(1):861. (PMID: 29021520)
Microbiome. 2018 Mar 21;6(1):55. (PMID: 29562936)
Cell Metab. 2022 Oct 4;34(10):1514-1531.e7. (PMID: 36027914)
J Nutr. 2003 Jul;133(7 Suppl):2485S-2493S. (PMID: 12840228)
Science. 2021 Jul 23;373(6553):. (PMID: 34083450)
Nat Neurosci. 2022 Jan;25(1):20-25. (PMID: 34811521)
Nat Rev Microbiol. 2023 Aug;21(8):535-550. (PMID: 37138047)
Nat Commun. 2020 Aug 21;11(1):4183. (PMID: 32826893)
Gut Microbes. 2022 Jan-Dec;14(1):2125739. (PMID: 36151874)
Immunity. 2018 Mar 20;48(3):514-529.e6. (PMID: 29548672)
Front Microbiol. 2022 Feb 11;13:819523. (PMID: 35222337)
Sci Rep. 2020 Oct 26;10(1):18270. (PMID: 33106549)
Nat Aging. 2022 Sep;2(9):837-850. (PMID: 37118504)
Brain Behav Immun. 2021 Jan;91:703-715. (PMID: 33148438)
Clin Nutr ESPEN. 2021 Feb;41:104-109. (PMID: 33487251)
Lancet Public Health. 2022 Feb;7(2):e105-e125. (PMID: 34998485)
N Engl J Med. 2022 Jan 20;386(3):220-229. (PMID: 35045228)
Nat Commun. 2023 Feb 18;14(1):926. (PMID: 36801916)
Nat Rev Microbiol. 2021 Feb;19(2):77-94. (PMID: 32968241)
Brain Behav Immun. 2022 Nov;106:307-321. (PMID: 36126853)
NPJ Parkinsons Dis. 2021 Nov 16;7(1):100. (PMID: 34785689)
Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19376-19387. (PMID: 32719140)
J Exp Med. 2019 Nov 4;216(11):2546-2561. (PMID: 31601677)
Nat Immunol. 2016 Nov;17(11):1300-1311. (PMID: 27668799)
Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14968-73. (PMID: 21873225)
Neurochem Int. 2020 May;135:104692. (PMID: 32032636)
Sci Transl Med. 2020 Feb 5;12(529):. (PMID: 32024799)
Mol Psychiatry. 2023 Oct;28(10):4438-4450. (PMID: 37495886)
Nat Rev Neurol. 2020 Dec;16(12):661-673. (PMID: 32939050)
Glia. 2021 Aug;69(8):2006-2022. (PMID: 33942391)
Nat Metab. 2021 Jun;3(6):737-750. (PMID: 34158655)
Gut Microbes. 2023 Dec;15(2):2252764. (PMID: 37671803)
Proc Natl Acad Sci U S A. 2020 May 26;117(21):11648-11657. (PMID: 32398370)
Cell. 2021 Feb 18;184(4):1000-1016.e27. (PMID: 33508229)
Chem Biol Interact. 2021 May 25;341:109452. (PMID: 33785315)
CNS Neurosci Ther. 2023 Jun;29(6):1690-1704. (PMID: 36890624)
Mov Disord. 2015 Sep;30(10):1351-60. (PMID: 26179554)
Food Res Int. 2022 May;155:111067. (PMID: 35400445)
J Prev Alzheimers Dis. 2021;8(4):483-494. (PMID: 34585224)
Nat Rev Immunol. 2022 Nov;22(11):657-673. (PMID: 35246670)
Cell. 2020 Jun 25;181(7):1661-1679.e22. (PMID: 32526207)
Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):E197-205. (PMID: 22167804)
Mol Neurobiol. 2012 Oct;46(2):475-86. (PMID: 22773138)
Cell Mol Immunol. 2023 Apr;20(4):341-350. (PMID: 36854801)
Cell Host Microbe. 2018 Jan 10;23(1):27-40.e7. (PMID: 29276171)
NPJ Biofilms Microbiomes. 2016 Jul 06;2:16009. (PMID: 28721246)
Glia. 2022 May;70(5):935-960. (PMID: 35092321)
Gut Microbes. 2022 Jan-Dec;14(1):2102878. (PMID: 35903003)
Benef Microbes. 2019 May 28;10(5):511-520. (PMID: 31090457)
Nat Cardiovasc Res. 2022 Feb;1(2):108-115. (PMID: 35450117)
Int J Biol Macromol. 2023 Jan 15;225:974-986. (PMID: 36402384)
Commun Biol. 2022 Dec 7;5(1):1340. (PMID: 36477191)
Int J Mol Sci. 2023 Jan 11;24(2):. (PMID: 36674935)
Nature. 2023 Jul;619(7970):572-584. (PMID: 37468586)
Lancet Neurol. 2017 May;16(5):351-359. (PMID: 28336296)
Nat Commun. 2019 Jan 18;10(1):310. (PMID: 30659181)
Signal Transduct Target Ther. 2023 May 3;8(1):177. (PMID: 37137892)
Brain Behav Immun. 2020 Nov;90:26-46. (PMID: 32739365)
Mol Psychiatry. 2022 Aug;27(8):3385-3395. (PMID: 35538193)
Nat Biotechnol. 2022 Jun;40(6):921-931. (PMID: 35241840)
Neurotox Res. 2009 May;15(4):332-47. (PMID: 19384567)
Nat Commun. 2019 Oct 3;10(1):4505. (PMID: 31582752)
Brain. 2020 May 1;143(5):1476-1497. (PMID: 32355963)
Nat Immunol. 2021 May;22(5):586-594. (PMID: 33859405)
Nat Commun. 2021 Oct 15;12(1):6021. (PMID: 34654818)
Nat Commun. 2023 Mar 11;14(1):1348. (PMID: 36906623)
Int J Mol Sci. 2022 May 25;23(11):. (PMID: 35682631)
Brain. 2022 Dec 19;145(12):4425-4439. (PMID: 35088843)
Am J Clin Nutr. 2022 Oct 6;116(4):928-942. (PMID: 36055959)
Ageing Res Rev. 2023 Aug;89:101994. (PMID: 37385351)
Neurobiol Dis. 2022 Aug;170:105780. (PMID: 35654277)
Cell Host Microbe. 2023 Apr 12;31(4):472-484. (PMID: 37054670)
Cell Host Microbe. 2022 Jun 8;30(6):848-862.e7. (PMID: 35483363)
Sci Adv. 2023 Mar 15;9(11):eade0997. (PMID: 36930714)
Cells. 2022 Nov 17;11(22):. (PMID: 36429082)
Crit Rev Food Sci Nutr. 2022 Oct 26;:1-10. (PMID: 36287024)
Sci Rep. 2021 Oct 25;11(1):21011. (PMID: 34697401)
Neuron. 2022 Nov 2;110(21):3458-3483. (PMID: 36327895)
Nat Commun. 2022 Nov 15;13(1):6958. (PMID: 36376318)
Mol Neurodegener. 2019 Aug 16;14(1):34. (PMID: 31419995)
NPJ Parkinsons Dis. 2022 Apr 21;8(1):48. (PMID: 35449203)
Int J Neuropsychopharmacol. 2016 Aug 12;19(8):. (PMID: 26912607)
Nat Neurosci. 2015 Jul;18(7):965-77. (PMID: 26030851)
Gut. 2022 Nov;71(11):2233-2252. (PMID: 35017199)
Int J Mol Sci. 2022 Oct 04;23(19):. (PMID: 36233056)
J Alzheimers Dis. 2022;88(1):75-95. (PMID: 35570493)
Alzheimers Res Ther. 2018 Dec 22;10(1):124. (PMID: 30579367)
Alzheimers Res Ther. 2022 Oct 11;14(1):152. (PMID: 36217192)
Acta Neurol Scand. 2020 Mar;141(3):250-255. (PMID: 31715011)
Nature. 2022 Mar;603(7903):885-892. (PMID: 35165441)
Obes Rev. 2023 Aug;24(8):e13573. (PMID: 37165483)
Biology (Basel). 2021 Apr 13;10(4):. (PMID: 33924344)
Mol Nutr Food Res. 2022 Oct;66(19):e2200265. (PMID: 35975737)
Nat Rev Immunol. 2024 Feb;24(2):91-102. (PMID: 37604896)
Neurology. 2021 May 11;96(19):e2395-e2406. (PMID: 33766994)
Cell. 2016 Dec 1;167(6):1469-1480.e12. (PMID: 27912057)
J Cell Physiol. 2017 Aug;232(8):2231-2245. (PMID: 27987324)
Nature. 2020 Jun;582(7810):89-94. (PMID: 32483373)
BMC Microbiol. 2017 Sep 13;17(1):194. (PMID: 28903732)
Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25311-25321. (PMID: 31740610)
Signal Transduct Target Ther. 2022 Jul 6;7(1):217. (PMID: 35794091)
Signal Transduct Target Ther. 2022 Nov 7;7(1):374. (PMID: 36336680)
Mucosal Immunol. 2018 May;11(3):752-762. (PMID: 29411774)
Trends Neurosci. 2021 Oct;44(10):837-848. (PMID: 34334233)
Brain Behav Immun. 2022 Jan;99:203-217. (PMID: 34673174)
Neuropsychopharmacology. 2023 May;48(6):963-974. (PMID: 36932179)
J Neurosci. 2006 Oct 4;26(40):10129-40. (PMID: 17021169)
Microbiome. 2021 May 18;9(1):113. (PMID: 34006335)
Cell. 2021 Apr 1;184(7):1740-1756.e16. (PMID: 33705688)
Physiol Rep. 2015 Apr;3(4):. (PMID: 25847918)
J Neuroinflammation. 2019 Aug 9;16(1):165. (PMID: 31399117)
Nat Rev Neurosci. 2022 Feb;23(2):115-128. (PMID: 34907352)
Gut. 2019 May;68(5):829-843. (PMID: 30554160)
Cell. 2021 Jul 22;184(15):4048-4063.e32. (PMID: 34233165)
Brain Behav Immun. 2023 Jan;107:53-61. (PMID: 36150585)
Nat Commun. 2023 Sep 26;14(1):6009. (PMID: 37752107)
Cell Mol Gastroenterol Hepatol. 2021;11(1):221-248. (PMID: 32795610)
Nature. 2021 Feb;590(7846):473-479. (PMID: 33408417)
Int Immunopharmacol. 2019 Jul;72:166-175. (PMID: 30986644)
FASEB J. 2015 Apr;29(4):1395-403. (PMID: 25550456)
Neuron. 2023 Jul 5;111(13):2021-2037.e12. (PMID: 37105172)
Nature. 2018 Feb 8;554(7691):244-248. (PMID: 29420469)
Nat Aging. 2022 Nov;2(11):1024-1039. (PMID: 37118092)
Nutrients. 2023 Apr 01;15(7):. (PMID: 37049578)
Nat Metab. 2023 May;5(5):777-788. (PMID: 37165176)
Nat Med. 2021 Sep;27(9):1592-1599. (PMID: 34446931)
Microbiome. 2023 Feb 21;11(1):30. (PMID: 36810115)
J Exp Med. 2022 Jan 3;219(1):. (PMID: 34854884)
Food Funct. 2023 Mar 20;14(6):2881-2895. (PMID: 36883968)
JAMA. 2020 Feb 11;323(6):548-560. (PMID: 32044947)
NPJ Parkinsons Dis. 2022 Mar 24;8(1):31. (PMID: 35332158)
Nutr Diabetes. 2020 Apr 22;10(1):12. (PMID: 32321934)
J Neuroinflammation. 2014 Mar 19;11:50. (PMID: 24645669)
Nature. 2012 Nov 29;491(7426):717-23. (PMID: 23051753)
Nature. 2021 Nov;599(7885):458-464. (PMID: 34325466)
Microbiome. 2021 Nov 27;9(1):235. (PMID: 34836554)
Nat Microbiol. 2019 Dec;4(12):2064-2073. (PMID: 31477894)
Sci Adv. 2019 Feb 06;5(2):eaau8317. (PMID: 30775438)
Nat Commun. 2021 Nov 15;12(1):6565. (PMID: 34782623)
Aging Cell. 2018 Aug;17(4):e12768. (PMID: 29749694)
Nat Immunol. 2023 Sep;24(9):1473-1486. (PMID: 37580603)
Mol Psychiatry. 2023 Jan;28(1):217-229. (PMID: 36258018)
JAMA Neurol. 2014 Sep;71(9):1102-10. (PMID: 25023276)
Science. 2019 Oct 25;366(6464):. (PMID: 31649166)
Commun Biol. 2023 Jun 23;6(1):665. (PMID: 37353538)
Cell. 2022 Oct 27;185(22):4135-4152.e22. (PMID: 36257314)
Front Mol Neurosci. 2020 Aug 12;13:138. (PMID: 32903435)
Cell Host Microbe. 2023 May 10;31(5):712-733. (PMID: 37167953)
Mol Neurobiol. 2012 Jun;45(3):440-54. (PMID: 22438081)
Nat Rev Chem. 2023 May;7(5):319-339. (PMID: 37117817)
EMBO J. 2021 Apr 1;40(7):e106177. (PMID: 33694180)
Sci Rep. 2017 Feb 08;7:41802. (PMID: 28176819)
Nature. 2023 Jun;618(7964):349-357. (PMID: 37258678)
Prog Neurobiol. 2012 Oct;99(1):15-41. (PMID: 22766041)
Nat Commun. 2021 Oct 29;12(1):6237. (PMID: 34716339)
Science. 2012 Apr 27;336(6080):489-93. (PMID: 22442383)
Nat Neurosci. 2023 Sep;26(9):1489-1504. (PMID: 37620442)
Nat Rev Neurol. 2022 Dec;18(12):735-746. (PMID: 36376595)
Cell. 2022 Sep 1;185(18):3441-3456.e19. (PMID: 36055202)
Nat Neurosci. 2023 Jun;26(6):970-982. (PMID: 37264161)
Cell. 2019 Aug 22;178(5):1245-1259.e14. (PMID: 31402174)
Clin Neurol Neurosurg. 2021 Aug;207:106791. (PMID: 34237681)
Aging Dis. 2020 Oct 1;11(5):1029-1045. (PMID: 33014520)
iScience. 2021 Dec 24;25(1):103687. (PMID: 35059604)
Autophagy. 2020 Dec;16(12):2193-2205. (PMID: 32003282)
iScience. 2022 Nov 23;25(12):105648. (PMID: 36505934)
Food Funct. 2023 Jul 31;14(15):6828-6839. (PMID: 37470081)
Microb Pathog. 2021 Nov;160:105187. (PMID: 34530073)
Gut Microbes. 2023 Jan-Dec;15(1):2190306. (PMID: 36945116)
Nature. 2022 Mar;603(7903):907-912. (PMID: 35296854)
Food Funct. 2022 Oct 3;13(19):10013-10022. (PMID: 36069253)
Transl Neurodegener. 2020 Nov 26;9(1):42. (PMID: 33239064)
Neurology. 2022 Feb 22;98(8):e848-e858. (PMID: 34996879)
Neurobiol Dis. 2020 Feb;135:104268. (PMID: 30194046)
Nature. 2012 Feb 29;483(7388):222-6. (PMID: 22388814)
Mucosal Immunol. 2022 Jun;15(6):1095-1113. (PMID: 36180583)
Nat Rev Gastroenterol Hepatol. 2022 Jul;19(7):432-450. (PMID: 35165436)
Nat Microbiol. 2019 Apr;4(4):623-632. (PMID: 30718848)
Mov Disord. 2022 Aug;37(8):1612-1623. (PMID: 35699244)
Nat Immunol. 2023 Jan;24(1):19-29. (PMID: 36596896)
Nat Neurosci. 2021 Mar;24(3):312-325. (PMID: 33589835)
Cell. 2022 Sep 15;185(19):3501-3519.e20. (PMID: 36041436)
Signal Transduct Target Ther. 2023 Jul 12;8(1):267. (PMID: 37433768)
J Neuroimmunol. 2020 Nov 15;348:577390. (PMID: 32956951)
Geroscience. 2021 Feb;43(1):377-394. (PMID: 32862276)
J Agric Food Chem. 2023 Mar 22;71(11):4646-4655. (PMID: 36888896)
Nature. 2018 May;557(7707):724-728. (PMID: 29769726)
Front Aging Neurosci. 2022 Aug 16;14:925227. (PMID: 36051303)
Nat Rev Microbiol. 2023 Apr;21(4):236-247. (PMID: 36253479)
Microbiome. 2020 Oct 2;8(1):143. (PMID: 33008466)
Cell Rep Med. 2020 Oct 20;1(7):100120. (PMID: 33103129)
Neurosci Biobehav Rev. 2020 May;112:227-241. (PMID: 32032654)
Biomaterials. 2023 Mar;294:122005. (PMID: 36701997)
J Pharm Anal. 2023 Oct;13(10):1153-1167. (PMID: 38024855)
Clin Nutr. 2019 Jun;38(3):1031-1035. (PMID: 29891223)
Nature. 2022 Feb;602(7898):647-653. (PMID: 35165440)
Nat Commun. 2023 May 2;14(1):2501. (PMID: 37130861)
Front Aging Neurosci. 2023 May 25;15:1162057. (PMID: 37346147)
J Alzheimers Dis. 2022;86(4):1875-1895. (PMID: 35253754)
J Neurochem. 2023 Nov;167(4):520-537. (PMID: 37822142)
Cell. 2016 Nov 17;167(5):1339-1353.e21. (PMID: 27863247)
Nutrients. 2022 Nov 04;14(21):. (PMID: 36364939)
Nat Rev Neurosci. 2023 Jan;24(1):23-39. (PMID: 36316501)
Brain. 2022 Apr 29;145(3):964-978. (PMID: 34919646)
Nat Rev Microbiol. 2023 Jun;21(6):347-360. (PMID: 36539611)
Clin Sci (Lond). 2022 Feb 25;136(4):291-307. (PMID: 35194640)
Nat Rev Clin Oncol. 2023 Oct;20(10):697-715. (PMID: 37488231)
Nat Rev Immunol. 2023 Jan;23(1):9-23. (PMID: 35534624)
Nat Med. 2019 Jul;25(7):1104-1109. (PMID: 31235964)
Mol Psychiatry. 2023 Apr;28(4):1611-1621. (PMID: 36914812)
Nat Metab. 2019 Dec;1(12):1177-1188. (PMID: 32694672)
Alzheimers Dement. 2021 Nov;17(11):1769-1778. (PMID: 34636485)
Elife. 2021 Apr 13;10:. (PMID: 33845942)
Front Aging Neurosci. 2022 Oct 31;14:1032494. (PMID: 36389063)
Nat Nanotechnol. 2023 Jun;18(6):617-627. (PMID: 36973397)
Nat Rev Endocrinol. 2023 Apr;19(4):201-216. (PMID: 36509857)
Exp Neurol. 2017 Sep;295:77-87. (PMID: 28552716)
Neurobiol Dis. 2013 Feb;50:21-9. (PMID: 22974733)
J Neurol. 2011 Jun;258(6):982-90. (PMID: 21181542)
Mol Ther. 2019 Jan 2;27(1):87-101. (PMID: 30446391)
Nat Rev Neurol. 2021 Mar;17(3):157-172. (PMID: 33318676)
Brain Res. 2020 Nov 1;1746:147023. (PMID: 32710901)
Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):491-502. (PMID: 28611480)
Aging (Albany NY). 2019 Oct 14;11(19):8642-8663. (PMID: 31612864)
Nature. 2019 Apr;568(7753):499-504. (PMID: 30745586)
Cell. 2015 Apr 9;161(2):264-76. (PMID: 25860609)
Nat Rev Neurosci. 2021 Nov;22(11):657-673. (PMID: 34545240)
Front Cell Infect Microbiol. 2022 Mar 11;12:839526. (PMID: 35360111)
Glia. 2013 Mar;61(3):409-19. (PMID: 23281114)
Nat Microbiol. 2021 May;6(5):563-573. (PMID: 33820962)
J Agric Food Chem. 2023 Jun 14;71(23):8877-8893. (PMID: 37267589)
Brain Behav Immun. 2022 May;102:151-160. (PMID: 35217173)
Front Pharmacol. 2017 Jun 12;8:370. (PMID: 28659803)
J Exp Med. 2019 Jul 1;216(7):1542-1560. (PMID: 31097468)
Neuroimage Clin. 2023;37:103322. (PMID: 36680976)
Cells. 2020 Apr 29;9(5):. (PMID: 32365642)
Clin Ther. 2017 Feb;39(2):322-336. (PMID: 28129947)
Nat Rev Gastroenterol Hepatol. 2021 Aug;18(8):559-570. (PMID: 33742166)
Neurobiol Dis. 2020 Sep;143:104963. (PMID: 32593752)
Nat Rev Drug Discov. 2019 May;18(5):379-401. (PMID: 30760888)
Nature. 2019 Dec;576(7785):143-148. (PMID: 31776512)
Nat Commun. 2021 Jun 11;12(1):3562. (PMID: 34117246)
Nat Commun. 2014 Jun 13;5:4159. (PMID: 24923909)
Cell. 2021 Sep 30;184(20):5089-5106.e21. (PMID: 34555357)
Nature. 2022 Nov;611(7937):769-779. (PMID: 36385529)
Nat Genet. 2019 Mar;51(3):414-430. (PMID: 30820047)
Cell. 2022 Oct 27;185(22):4153-4169.e19. (PMID: 36306735)
Science. 2023 Jan 13;379(6628):eadd1236. (PMID: 36634180)
Nat Immunol. 2023 Jul;24(7):1173-1187. (PMID: 37291385)
Int J Biol Macromol. 2023 Mar 31;232:123488. (PMID: 36731694)
Nat Neurosci. 2023 Jun;26(6):942-954. (PMID: 37231108)
Mov Disord. 2023 Aug;38(8):1493-1502. (PMID: 37246815)
Nat Rev Drug Discov. 2023 Mar;22(3):185-212. (PMID: 36543887)
Nat Neurosci. 2021 Dec;24(12):1673-1685. (PMID: 34782793)
Am J Clin Nutr. 2023 Jun;117(6):1096-1109. (PMID: 37028557)
Nature. 2023 Jan;613(7942):120-129. (PMID: 36517604)
Nature. 2020 Jan;577(7790):399-404. (PMID: 31915375)
ACS Nano. 2022 Apr 26;16(4):6049-6063. (PMID: 35362965)
Nat Rev Neurol. 2019 Oct;15(10):565-581. (PMID: 31501588)
Nat Neurosci. 2023 Oct;26(10):1663-1669. (PMID: 37653126)
Nat Rev Gastroenterol Hepatol. 2022 Dec;19(12):805-813. (PMID: 36050385)
Cell Stem Cell. 2010 Oct 8;7(4):483-95. (PMID: 20887954)
Lancet. 2017 Oct 7;390(10103):1664-1675. (PMID: 28781108)
Nat Neurosci. 2023 Feb;26(2):181-195. (PMID: 36593328)
Neuroscience. 2013 Aug 29;246:281-90. (PMID: 23673277)
Front Neurol. 2018 Aug 15;9:662. (PMID: 30158897)
Nat Med. 2018 Jul;24(7):931-938. (PMID: 29892066)
Nature. 2019 Jun;570(7759):65-70. (PMID: 31118513)
Biomed Pharmacother. 2023 Sep;165:115100. (PMID: 37418977)
Nature. 2017 Nov 23;551(7681):507-511. (PMID: 29143816)
Metabolites. 2018 Oct 31;8(4):. (PMID: 30384419)
Neurology. 2023 Aug 15;101(7):e690-e698. (PMID: 37344230)
Pharmacol Res. 2022 Dec;186:106550. (PMID: 36372278)
Trends Microbiol. 2021 Aug;29(8):667-685. (PMID: 33551269)
Sci Adv. 2021 May 21;7(21):. (PMID: 34020948)
Neurochem Res. 2021 Nov;46(11):3050-3058. (PMID: 34347266)
BMC Med. 2020 Jun 17;18(1):153. (PMID: 32546239)
Nat Chem Biol. 2021 Oct;17(10):1027-1036. (PMID: 34552221)
Alzheimers Dement (N Y). 2022 Feb 23;8(1):e12268. (PMID: 35229024)
Sci Rep. 2021 Jan 12;11(1):803. (PMID: 33436868)
J Control Release. 2022 Sep;349:184-205. (PMID: 35798093)
N Engl J Med. 2019 Nov 21;381(21):2043-2050. (PMID: 31665575)
Sci Rep. 2022 Jan 27;12(1):1459. (PMID: 35087114)
Alzheimers Res Ther. 2021 Feb 12;13(1):44. (PMID: 33579351)
Sci Transl Med. 2022 Jul 27;14(655):eabp8869. (PMID: 35895835)
Biol Rev Camb Philos Soc. 2022 Feb;97(1):217-250. (PMID: 34549510)
Nature. 2015 Jan 8;517(7533):205-8. (PMID: 25337874)
J Nanobiotechnology. 2022 Oct 7;20(1):439. (PMID: 36207740)
Neurology. 2016 Sep 20;87(12):1274-80. (PMID: 27543643)
Mov Disord. 2017 Oct;32(10):1487-1491. (PMID: 28681931)
J Gerontol A Biol Sci Med Sci. 2022 Jun 1;77(6):1245-1249. (PMID: 34525197)
Acta Neuropathol Commun. 2021 Jan 5;9(1):1. (PMID: 33402227)
Cell Mol Neurobiol. 2023 Jul;43(5):2377-2384. (PMID: 36107359)
Nat Microbiol. 2019 Mar;4(3):396-403. (PMID: 30531975)
iScience. 2022 Mar 25;25(5):104158. (PMID: 35494230)
Nat Rev Drug Discov. 2022 May;21(5):339-358. (PMID: 35173313)
Metabolites. 2021 Jan 04;11(1):. (PMID: 33406628)
Biomolecules. 2022 Feb 19;12(2):. (PMID: 35204833)
Mol Neurodegener. 2021 Feb 8;16(1):6. (PMID: 33557896)
Ann Neurol. 2023 Sep;94(3):486-501. (PMID: 37314861)
Neurobiol Dis. 2022 Jun 15;168:105697. (PMID: 35314319)
Mol Neurodegener. 2022 Feb 2;17(1):13. (PMID: 35109920)
Cytokine Growth Factor Rev. 2017 Jun;35:71-84. (PMID: 28285098)
Nat Rev Mol Cell Biol. 2020 Aug;21(8):421-438. (PMID: 32457508)
J Alzheimers Dis. 2013;35(4):697-713. (PMID: 23481688)
Fluids Barriers CNS. 2023 Feb 6;20(1):12. (PMID: 36747230)
Nature. 2016 Jul 21;535(7612):376-81. (PMID: 27409811)
Nat Immunol. 2019 Sep;20(9):1110-1128. (PMID: 31406380)
Nat Rev Immunol. 2023 Nov;23(11):749-762. (PMID: 37316560)
Nat Metab. 2020 Jan;2(1):9-31. (PMID: 32694684)
Nat Med. 2016 Jun;22(6):586-97. (PMID: 27158906)
Chem Biol Interact. 2023 Sep 1;382:110638. (PMID: 37473910)
Brain Commun. 2020 Jul 24;2(2):fcaa110. (PMID: 33005892)
Cell Stem Cell. 2022 Aug 4;29(8):1197-1212.e8. (PMID: 35931030)
Nat Rev Immunol. 2024 Jan;24(1):49-63. (PMID: 37452201)
Nat Microbiol. 2022 Sep;7(9):1404-1418. (PMID: 35982310)
Nat Rev Drug Discov. 2022 Aug;21(8):578-600. (PMID: 35668103)
MedComm (2020). 2023 May 16;4(3):e268. (PMID: 37200942)
Mol Neurodegener. 2023 Jul 4;18(1):44. (PMID: 37403161)
Brain. 2017 Mar 1;140(3):792-803. (PMID: 28122877)
Int J Biol Macromol. 2022 Jul 31;213:404-415. (PMID: 35661666)
Nature. 2021 May;593(7858):255-260. (PMID: 33911285)
Microbiome. 2021 Nov 17;9(1):226. (PMID: 34784980)
NPJ Parkinsons Dis. 2023 Jan 6;9(1):1. (PMID: 36609384)
Nat Rev Drug Discov. 2017 Dec;16(12):829-842. (PMID: 29075003)
Nat Rev Gastroenterol Hepatol. 2022 Dec;19(12):785-803. (PMID: 36097076)
Clin Infect Dis. 2021 Jun 1;72(11):e876-e880. (PMID: 33159210)
Acta Neuropathol Commun. 2019 Jul 5;7(1):107. (PMID: 31277703)
Brain Behav Immun. 2020 Oct;89:67-86. (PMID: 32479993)
PLoS Med. 2021 May 27;18(5):e1003615. (PMID: 34043628)
JCI Insight. 2023 May 22;8(10):. (PMID: 37212281)
Nat Microbiol. 2023 May;8(5):787-802. (PMID: 37069399)
Nat Neurosci. 2014 Apr;17(4):513-21. (PMID: 24584051)
Lancet Neurol. 2022 Jul;21(7):645-658. (PMID: 35716694)
Nat Rev Neurol. 2019 Sep;15(9):540-555. (PMID: 31324897)
Endocrinology. 2013 Oct;154(10):3643-51. (PMID: 23892476)
CNS Neurosci Ther. 2023 Nov;29(11):3657-3666. (PMID: 37144597)
Nature. 2023 Sep;621(7980):821-829. (PMID: 37586410)
Tissue Cell. 2023 Apr;81:102034. (PMID: 36753814)
Am J Clin Nutr. 2022 Oct 6;116(4):862-874. (PMID: 36026526)
Nat Commun. 2019 Apr 4;10(1):1541. (PMID: 30948723)
Microb Cell Fact. 2021 May 13;20(1):98. (PMID: 33985520)
Nat Commun. 2022 Apr 19;13(1):2117. (PMID: 35440537)
Acta Neuropathol. 2021 May;141(5):681-696. (PMID: 33609158)
Gut. 2020 Dec;69(12):2232-2243. (PMID: 32917747)
Sci Rep. 2020 Aug 24;10(1):14112. (PMID: 32839473)
Cell. 2022 Oct 27;185(22):4170-4189.e20. (PMID: 36240781)
Microbiome. 2023 Feb 14;11(1):27. (PMID: 36782241)
Gut. 2022 May;71(5):1020-1032. (PMID: 35105664)
Sci Rep. 2019 Aug 14;9(1):11814. (PMID: 31413350)
Cell Death Differ. 2021 Apr;28(4):1379-1397. (PMID: 33184465)
Signal Transduct Target Ther. 2023 Sep 22;8(1):359. (PMID: 37735487)
Cell Rep. 2023 Mar 28;42(3):112196. (PMID: 36871219)
Life Sci. 2023 Sep 1;328:121882. (PMID: 37356750)
Mol Psychiatry. 2021 Nov;26(11):6277-6292. (PMID: 33963281)
Nat Rev Endocrinol. 2019 Apr;15(4):226-237. (PMID: 30760847)
J Neurochem. 2019 Aug;150(4):441-452. (PMID: 30851189)
Glia. 2022 Jan;70(1):173-195. (PMID: 34661306)
Brain Behav Immun. 2022 Jan;99:132-146. (PMID: 34601012)
Eur Heart J. 2022 Feb 10;43(6):518-533. (PMID: 34597388)
Alzheimers Res Ther. 2021 Jan 9;13(1):20. (PMID: 33422142)
J Cereb Blood Flow Metab. 2020 Dec;40(1_suppl):S6-S24. (PMID: 32928017)
Microbiome. 2022 Apr 29;10(1):68. (PMID: 35501923)
Acta Pharm Sin B. 2020 Mar;10(3):475-487. (PMID: 32140393)
Sci Adv. 2023 Apr 5;9(14):eade1474. (PMID: 37018391)
Front Aging Neurosci. 2022 Nov 03;14:964429. (PMID: 36408109)
Dis Model Mech. 2019 Nov 15;13(2):. (PMID: 31597644)
Front Pharmacol. 2023 Sep 13;14:1205207. (PMID: 37771725)
Cell Rep. 2019 Oct 29;29(5):1164-1177.e5. (PMID: 31665631)
Cell Host Microbe. 2021 May 12;29(5):765-776.e3. (PMID: 33794185)
Brain. 2016 Sep;139(Pt 9):2486-502. (PMID: 27538418)
Acta Neuropathol. 2018 Sep;136(3):445-459. (PMID: 29943193)
Gut Microbes. 2021 Jan 1;13(1):1866974. (PMID: 33459114)
J Clin Invest. 2022 Sep 1;132(17):. (PMID: 35727638)
Elife. 2022 Nov 08;11:. (PMID: 36346385)
Signal Transduct Target Ther. 2023 Sep 13;8(1):345. (PMID: 37699892)
Nat Commun. 2023 Jun 8;14(1):3372. (PMID: 37291151)
Cell Host Microbe. 2018 Jun 13;23(6):705-715. (PMID: 29902436)
Nat Rev Gastroenterol Hepatol. 2014 Aug;11(8):506-14. (PMID: 24912386)
Nature. 2013 Dec 19;504(7480):446-50. (PMID: 24226770)
Lancet Diabetes Endocrinol. 2021 Mar;9(3):165-173. (PMID: 33549162)
Sci Rep. 2019 Mar 14;9(1):4572. (PMID: 30872738)
Front Nutr. 2021 Jun 30;8:650053. (PMID: 34277679)
Mov Disord. 2020 Jul;35(7):1208-1217. (PMID: 32357258)
Nat Med. 2021 Feb;27(2):333-343. (PMID: 33574608)
Brain Behav Immun. 2023 Feb;108:309-327. (PMID: 36535610)
Nutrients. 2019 Feb 01;11(2):. (PMID: 30717153)
J Neuroinflammation. 2022 Jun 15;19(1):147. (PMID: 35706029)
Nat Commun. 2023 Jan 6;14(1):95. (PMID: 36609402)
Front Neuroendocrinol. 2023 Jul;70:101082. (PMID: 37414372)
EBioMedicine. 2020 May;55:102766. (PMID: 32408110)
Am J Clin Nutr. 2011 Jul;94(1):58-65. (PMID: 21543530)
Mov Disord. 2021 Dec;36(12):2888-2900. (PMID: 34494685)
Brain Behav Immun. 2020 Nov;90:108-137. (PMID: 32800927)
Cell. 2020 Jan 23;180(2):221-232. (PMID: 31978342)
Sci Transl Med. 2019 Aug 14;11(505):. (PMID: 31413143)
Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141. (PMID: 33353981)
Front Aging Neurosci. 2017 Dec 08;9:403. (PMID: 29276488)
Nature. 2023 Aug;620(7973):374-380. (PMID: 37532932)
Nutrients. 2022 Nov 05;14(21):. (PMID: 36364950)
Exp Gerontol. 2021 Jul 15;150:111376. (PMID: 33905875)
J Alzheimers Dis. 2020;74(1):91-99. (PMID: 31958090)
Nat Commun. 2022 Dec 6;13(1):7129. (PMID: 36473853)
Nature. 2023 Sep;621(7979):577-585. (PMID: 37557915)
Gut. 2022 Apr;71(4):724-733. (PMID: 33926968)
Nat Med. 2014 Aug;20(8):886-96. (PMID: 24973918)
Clin Nutr. 2022 Nov;41(11):2565-2576. (PMID: 36228569)
Science. 2015 Aug 28;349(6251):993-7. (PMID: 26272906)
Glia. 2022 Jan;70(1):89-105. (PMID: 34487590)
Gastroenterology. 2021 Apr;160(5):1486-1501. (PMID: 33493503)
Microbiome. 2023 Aug 2;11(1):169. (PMID: 37533066)
Lancet Gastroenterol Hepatol. 2023 Jan;8(1):66-80. (PMID: 36334596)
Acta Pharm Sin B. 2022 Aug;12(8):3298-3312. (PMID: 35967282)
Mol Nutr Food Res. 2022 Sep;66(18):e2200164. (PMID: 35819092)
Brain. 2018 Sep 1;141(9):2740-2754. (PMID: 30052812)
Cell. 2019 Oct 3;179(2):292-311. (PMID: 31585077)
Cell Biosci. 2023 Oct 3;13(1):186. (PMID: 37789469)
N Engl J Med. 2016 Dec 15;375(24):2369-2379. (PMID: 27974040)
Nature. 2016 Jun 08;534(7606):213-7. (PMID: 27279214)
Int J Mol Sci. 2020 Apr 11;21(8):. (PMID: 32290475)
Immunity. 2021 Oct 12;54(10):2194-2208. (PMID: 34644556)
Int J Biol Macromol. 2023 Aug 30;247:125787. (PMID: 37437678)
Science. 2018 Mar 9;359(6380):1151-1156. (PMID: 29590046)
Cell Metab. 2022 Dec 6;34(12):1947-1959.e5. (PMID: 36476934)
Signal Transduct Target Ther. 2021 Feb 24;6(1):77. (PMID: 33623004)
Microbiome. 2021 Jul 20;9(1):162. (PMID: 34284827)
Nature. 2019 Jun;570(7762):462-467. (PMID: 31158845)
Nat Neurosci. 2022 Mar;25(3):295-305. (PMID: 35241804)
Biomedicines. 2022 Feb 13;10(2):. (PMID: 35203645)
Mol Neurodegener. 2022 Aug 24;17(1):55. (PMID: 36002854)
Mol Psychiatry. 2022 Aug;27(8):3396-3409. (PMID: 35546632)
Nutrients. 2021 Jan 14;13(1):. (PMID: 33466861)
Mol Neurodegener. 2023 Jul 6;18(1):45. (PMID: 37415149)
المشرفين على المادة: 0 (Prebiotics)
تواريخ الأحداث: Date Created: 20240215 Date Completed: 20240219 Latest Revision: 20240219
رمز التحديث: 20240219
مُعرف محوري في PubMed: PMC10869798
DOI: 10.1038/s41392-024-01743-1
PMID: 38360862
قاعدة البيانات: MEDLINE
الوصف
تدمد:2059-3635
DOI:10.1038/s41392-024-01743-1