دورية أكاديمية
Characterizing the burden of biliary tract cancers across 28 hospitals in Ontario, Canada.
| العنوان: | Characterizing the burden of biliary tract cancers across 28 hospitals in Ontario, Canada. |
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| المؤلفون: | Choi WJ; Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Roberts S; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Verma A; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Razak F; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., O'Kane GM; Department of Medical Oncology, Trinity St. James's Cancer Institute, Trinity College Dublin, Dublin, Ireland., Gallinger S; Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; University Health Network, HPB Surgical Oncology, Toronto, Ontario, Canada., Hirschfield G; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada., Hansen B; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.; Department of Epidemiology & Biostatistics, Erasmus MC, Rotterdam, the Netherlands., Sapisochin G; Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; University Health Network, HPB Surgical Oncology, Toronto, Ontario, Canada. |
| المصدر: | Cancer [Cancer] 2024 Jul 01; Vol. 130 (13), pp. 2294-2303. Date of Electronic Publication: 2024 Feb 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0142 (Electronic) Linking ISSN: 0008543X NLM ISO Abbreviation: Cancer Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2005- >: Hoboken, NJ : Wiley Original Publication: New York [etc.] Published for the American Cancer Society by J. Wiley [etc.] |
| مواضيع طبية MeSH: | Hospitalization*/statistics & numerical data , Biliary Tract Neoplasms*/epidemiology, Humans ; Ontario/epidemiology ; Female ; Male ; Aged ; Middle Aged ; Cholangiocarcinoma/epidemiology ; Length of Stay/statistics & numerical data ; Incidence ; Hospitals/statistics & numerical data ; Aged, 80 and over ; Hospital Mortality ; Cost of Illness ; Gallbladder Neoplasms/epidemiology ; Bile Duct Neoplasms/epidemiology |
| مستخلص: | Background and Aims: The incidence of biliary tract cancers (BTC) appears to be increasing worldwide. We analyzed the characteristics of BTC-related hospitalizations under medical services across 28 hospitals in Ontario, Canada. Methods: This study uses data collected by GEMINI, a hospital research data network. BTC-related hospitalizations from 2015 to 2021 under the Department of Medicine or intensive care unit were captured using the International Classification of Diseases, 10th revision, codes for intrahepatic cholangiocarcinoma (iCCA), extrahepatic cholangiocarcinoma, and gallbladder cancers. Results: A total of 4596 BTC-related hospitalizations (2720 iCCA, 1269 extrahepatic cholangiocarcinoma, 607 gallbladder cancers) were analyzed. The number of unique patients with BTC-related hospitalizations increased over time. For iCCA-related hospitalizations, the total number of hospitalizations increased (from 385 in 2016 to 420 in 2021, p = .005), the hospital length of stay decreased over the study period (mean 10 days [SD, 12] in 2016 to 9 days [SD, 8] in 2021, p = .04), and the number of in-hospital deaths was stable (from 68 [18%] in 2016 to 55 [13%] in 2021, p = .62). Other outcomes such as 30-day readmissions, medical imaging tests, intensive care unit-specific hospitalizations, and length of stay were stable over time for all cohorts. The cost of hospitalization for the BTC cohort increased from median $8203 CAD (interquartile range, 5063-15,543) in 2017 to $8507 CAD (interquartile range, 5345-14,755) in 2021. Conclusions: This real-world data analysis showed a rising number of patients with BTC-related hospitalizations and rising number of iCCA-related hospitalizations across 28 hospitals in Ontario between 2015 and 2021. (© 2024 American Cancer Society.) |
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| معلومات مُعتمدة: | 181365 Canada CAPMC CIHR; 181365 Canada CAPMC CIHR; Green Shield Canada Foundation; Division of General Internal Medicine, University of Toronto |
| فهرسة مساهمة: | Keywords: bile duct; cancer; cholangiocarcinoma; hospitalization; resource |
| تواريخ الأحداث: | Date Created: 20240216 Date Completed: 20240607 Latest Revision: 20240607 |
| رمز التحديث: | 20240610 |
| DOI: | 10.1002/cncr.35249 |
| PMID: | 38361443 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1097-0142 |
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| DOI: | 10.1002/cncr.35249 |