Laboratory Assessment of Molluscicidal Activities of Cannabis sativa , Acacia nilotica , and Tinospora cordifolia Against Snail Host of Fasciola spp.

التفاصيل البيبلوغرافية
العنوان:	Laboratory Assessment of Molluscicidal Activities of Cannabis sativa , Acacia nilotica , and Tinospora cordifolia Against Snail Host of Fasciola spp.
المؤلفون:	Singh NV; Department of Zoology, Deen Dayal Upadhyay Gorakhpur University, Gorakhpur, India., Singh A; Department of Zoology, Deen Dayal Upadhyay Gorakhpur University, Gorakhpur, India., Singh VK; Department of Zoology, Deen Dayal Upadhyay Gorakhpur University, Gorakhpur, India.
المصدر:	Vector borne and zoonotic diseases (Larchmont, N.Y.) [Vector Borne Zoonotic Dis] 2024 Jun; Vol. 24 (6), pp. 382-389. Date of Electronic Publication: 2024 Feb 16.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100965525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7759 (Electronic) Linking ISSN: 15303667 NLM ISO Abbreviation: Vector Borne Zoonotic Dis Subsets: MEDLINE
أسماء مطبوعة:	Original Publication: Larchmont, NY : Mary Ann Liebert, Inc., [2001-
مواضيع طبية MeSH:	Tinospora/chemistry , Plant Extracts/pharmacology , Plant Extracts/chemistry , Acacia/chemistry , Molluscacides/pharmacology , Cannabis/chemistry, Animals ; Plant Leaves/chemistry ; Lymnaea/drug effects ; Fasciola/drug effects ; Snails/parasitology ; Snails/drug effects
مستخلص:	Background: The potential molluscicidal extracts, obtained from indigenous plants Cannabis sativa , Acacia nilotica , and Tinospora cordifolia , were tested for toxicity against freshwater pulmonate snail Lymnaea acuminata , an intermediate host of Fasciola hepatica . The organic extracts had a significant effect on young snails. Materials and Methods: All organic extracts and column-purified fractions gave median lethal concentrations (19-100.05 mg/L; 24 h) that fell well within the threshold level of 100 mg/L, set for a potential molluscicide by the World Health Organization. Results: The toxicity of T. cordifolia stem acetone extract (96 h LC 50 : 16.08 mg/L) was more pronounced compared with C. sativa leaf ethanol extract (96 h LC 50 : 16.32 mg/L) and A. nilotica leaf ethanol extract (96 h LC 50 : 24.78 mg/L). β-caryophyllene, gallic acid, and berberine were characterized and identified as active molluscicidal components. Co-migration of β-caryophyllene (retardation factor [R f ] 0.95), gallic acid ( Rf 0.30), and berberine (R f 0.23) with column-purified parts of Cannabis sativa , Acacia nilotica , and Tinospora cordifolia on thin-layer chromatography demonstrates same R f value, that is, 0.95, 0.30, and 0.23, respectively. Conclusion: This study indicates that these extracts thus represent potential plant-derived molluscicides that are worthy of further investigations.
فهرسة مساهمة:	Keywords: Acacia nilotica; Cannabis sativa; Fasciola spp.; Lymnaea acuminata; Tinospora cordifolia; fascioliasis
المشرفين على المادة:	0 (Plant Extracts) 0 (Molluscacides)
تواريخ الأحداث:	Date Created: 20240216 Date Completed: 20240620 Latest Revision: 20240620
رمز التحديث:	20240620
DOI:	10.1089/vbz.2023.0073
PMID:	38364187
قاعدة البيانات:	MEDLINE

الوصف
تدمد:	1557-7759
DOI:	10.1089/vbz.2023.0073