دورية أكاديمية
أعرض في EDS

Association between ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M268T) polymorphisms and performance phenotypes in Brazilian swimmers.

التفاصيل البيبلوغرافية
العنوان: Association between ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M268T) polymorphisms and performance phenotypes in Brazilian swimmers.
المؤلفون: de Albuquerque-Neto SL; União Educacional do Nordeste (UNINORDESTE), João Pessoa, Paraíba, Brazil., Santos MAPD; Department of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, Piauí, Brazil. marcosedfisio@gmail.com.; Rede Nordeste de Biotecnologia (RENORBIO), Federal University of Piauí, Teresina, Piauí, Brazil. marcosedfisio@gmail.com., Silvino VO; Department of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, Piauí, Brazil.; Rede Nordeste de Biotecnologia (RENORBIO), Federal University of Piauí, Teresina, Piauí, Brazil., Herrera JJB; Brazilian Confederation of Aquatic Sports, Rio de Janeiro, Rio de Janeiro, Brazil., Rosa TS; Department of Physical Education, Catholic University of Brasília, Brasília, DF, Brazil., Silva GCB; Department of Physical Education, State University of Piauí, Barros Araújo Campus, Picos, Piauí, Brazil., Couto BP; School of Health and Behavioural Sciences, The University of the Sunshine Coast, Sippy Downs, QLD, Australia., Ferreira CP; Department of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, Piauí, Brazil.; Rede Nordeste de Biotecnologia (RENORBIO), Federal University of Piauí, Teresina, Piauí, Brazil., Silva AS; Associated Postgraduate Program in Physical Education of the Federal University of Pernambuco, Federal University of Paraíba, João Pessoa, Brazil., de Almeida SS; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.; Universidade Ibirapuera, São Paulo, São Paulo, Brazil.; Universidade Anhanguera, Guarulhos, São Paulo, Brazil., de Melo GF; Department of Physical Education, Catholic University of Brasília, Brasília, DF, Brazil.
المصدر: BMC sports science, medicine & rehabilitation [BMC Sports Sci Med Rehabil] 2024 Feb 19; Vol. 16 (1), pp. 50. Date of Electronic Publication: 2024 Feb 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101605016 Publication Model: Electronic Cited Medium: Print ISSN: 2052-1847 (Print) Linking ISSN: 20521847 NLM ISO Abbreviation: BMC Sports Sci Med Rehabil Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, [2013]-
مستخلص: Background: The influence of genetic polymorphisms on athletic performance has been widely explored. This study investigated the interactions between the polymorphisms ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M/T) and their association with endurance and strength phenotypes in Brazilian swimmers.
Methods: 123 athletes (aged 20-30 years) and 718 controls participated in the study. The athletes were divided into elite and sub-elite (N = 19 and 104, respectively) and strength and endurance experts (N = 98 and 25, respectively). Hardy-Weinberg equilibrium was observed in all groups.
Results: Considering the ACE polymorphism, it was observed a higher frequency of the DD genotype than expected in the strength experts of the elite group, whereas the strength experts sub-elite athletes had a higher frequency of the ID genotype (χ 2  = 8.17; p = 0.01). Subjects with XX genotypes of ACTN3 are more likely to belong to the athlete group when compared to the control group (OR = 1.79, p = 0.04). The DD homozygotes of the ACE are more likely to belong to the elite group with strength phenotypes than the group of sub-elite (OR = 7.96, p = 0.01) and elite strength experts compared to elite endurance (OR = 18.0, p = 0.03). However, no significant differences were observed in the allelic distribution of the polymorphisms evaluated when comparing Elite, sub-elite athletes and controls.
Conclusion: ACE and ACTN3 allele frequencies should be considered with regard to performance influencing factors in Brazilian swimmers.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Aerobic performance; Genetic polymorphisms; Strength; Swimming
تواريخ الأحداث: Date Created: 20240219 Latest Revision: 20240222
رمز التحديث: 20240222
مُعرف محوري في PubMed: PMC10877830
DOI: 10.1186/s13102-024-00828-2
PMID: 38374123
قاعدة البيانات: MEDLINE
الوصف
تدمد:2052-1847
DOI:10.1186/s13102-024-00828-2