دورية أكاديمية
Nonlinear elasticity and short-range mechanical coupling govern the rate and symmetry of mouth opening in Hydra .
| العنوان: | Nonlinear elasticity and short-range mechanical coupling govern the rate and symmetry of mouth opening in Hydra . |
|---|---|
| المؤلفون: | Goel T; Department of Physics, University of California San Diego, La Jolla, CA 92093, USA.; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.; Department of Biology, University of Maryland, College Park, MD 20742, USA., Adams EM; Department of Biology, Swarthmore College, Swarthmore, PA 19081, USA., Bialas AL; Department of Biology, Swarthmore College, Swarthmore, PA 19081, USA., Tran CM; Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Rowe T; Department of Physics, University of California San Diego, La Jolla, CA 92093, USA., Martin S; Department of Biology, Swarthmore College, Swarthmore, PA 19081, USA., Chandler M; Department of Biology, Swarthmore College, Swarthmore, PA 19081, USA., Schubert J; Department of Biology, Swarthmore College, Swarthmore, PA 19081, USA., Diamond PH; Department of Physics, University of California San Diego, La Jolla, CA 92093, USA., Collins ES; Department of Physics, University of California San Diego, La Jolla, CA 92093, USA.; Department of Biology, Swarthmore College, Swarthmore, PA 19081, USA.; Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. |
| المصدر: | Proceedings. Biological sciences [Proc Biol Sci] 2024 Feb 28; Vol. 291 (2017), pp. 20232123. Date of Electronic Publication: 2024 Feb 21. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Royal Society of London Country of Publication: England NLM ID: 101245157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2954 (Electronic) Linking ISSN: 09628452 NLM ISO Abbreviation: Proc Biol Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : Royal Society of London, c1990- |
| مواضيع طبية MeSH: | Hydra*/physiology, Animals ; Mouth/physiology ; Epithelium ; Biomechanical Phenomena ; Neurons |
| مستخلص: | Hydra has a tubular bilayered epithelial body column with a dome-shaped head on one end and a foot on the other. Hydra lacks a permanent mouth: its head epithelium is sealed. Upon neuronal activation, a mouth opens at the apex of the head which can exceed the body column diameter in seconds, allowing Hydra to ingest prey larger than itself. While the kinematics of mouth opening are well characterized, the underlying mechanism is unknown. We show that Hydra mouth opening is generated by independent local contractions that require tissue-level coordination. We model the head epithelium as an active viscoelastic nonlinear spring network. The model reproduces the size, timescale and symmetry of mouth opening. It shows that radial contractions, travelling inwards from the outer boundary of the head, pull the mouth open. Nonlinear elasticity makes mouth opening larger and faster, contrary to expectations. The model correctly predicts changes in mouth shape in response to external forces. By generating innervated : nerve-free chimera in experiments and simulations, we show that nearest-neighbour mechanical signalling suffices to coordinate mouth opening. Hydra mouth opening shows that in the absence of long-range chemical or neuronal signals, short-range mechanical coupling is sufficient to produce long-range order in tissue deformations. |
| References: | J Vis Exp. 2017 Jul 7;(125):. (PMID: 28715393) Curr Biol. 2017 Apr 24;27(8):1085-1097. (PMID: 28366745) J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2004 Aug;190(8):623-30. (PMID: 15168068) Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;87(2):321-4. (PMID: 2888575) Nature. 2007 May 31;447(7144):592-5. (PMID: 17538621) Lab Anim. 1970 Apr;4(1):139-54. (PMID: 5527814) Nat Methods. 2012 Jun 28;9(7):676-82. (PMID: 22743772) J Cell Sci. 1976 Jun;21(1):1-13. (PMID: 932105) Biol Bull. 1991 Dec;181(3):463-473. (PMID: 29304670) Biol Open. 2017 Aug 15;6(8):1137-1148. (PMID: 28630355) Integr Comp Biol. 2023 Dec 29;63(6):1442-1454. (PMID: 37355780) PLoS One. 2019 Oct 24;14(10):e0224221. (PMID: 31648269) J Exp Zool. 1968 Mar;167(3):283-93. (PMID: 4385250) Acta Biol Hung. 2008;59 Suppl:227-35. (PMID: 18652396) Curr Biol. 2019 Jun 3;29(11):1807-1817.e3. (PMID: 31130460) Compr Physiol. 2012 Oct;2(4):2369-92. (PMID: 23720251) Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10333-E10341. (PMID: 30309963) Development. 2013 Dec;140(23):4788-96. (PMID: 24255098) Tissue Cell. 1978;10(4):629-46. (PMID: 746538) Am J Physiol Lung Cell Mol Physiol. 2004 Nov;287(5):L1025-34. (PMID: 15246973) J Biophys Biochem Cytol. 1959 Dec;6:343-52. (PMID: 13845833) Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3365-73. (PMID: 26080418) J Exp Biol. 2015 Jul;218(Pt 14):2226-32. (PMID: 25987735) Biophys J. 2006 May 15;90(10):3796-805. (PMID: 16461394) J Cell Sci. 1978 Feb;29:17-33. (PMID: 627604) Cold Spring Harb Perspect Biol. 2015 Feb 02;7(2):a006023. (PMID: 25646377) Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2210439120. (PMID: 36897982) Science. 1987 Jul 3;237(4810):49-55. (PMID: 3037697) Proc Biol Sci. 2024 Feb 28;291(2017):20232123. (PMID: 38378148) Biochem Biophys Res Commun. 1998 Jul 30;248(3):584-90. (PMID: 9703970) Sci Rep. 2014 Jan 07;4:3573. (PMID: 24394722) J Morphol. 1981 Jun;168(3):321-329. (PMID: 30111002) Biophys J. 2016 Mar 8;110(5):1191-201. (PMID: 26958895) |
| فهرسة مساهمة: | Keywords: chimera; epithelium; nearest-neighbour interaction; strain hardening; viscoelastic |
| تواريخ الأحداث: | Date Created: 20240220 Date Completed: 20240222 Latest Revision: 20240224 |
| رمز التحديث: | 20240224 |
| مُعرف محوري في PubMed: | PMC10878823 |
| DOI: | 10.1098/rspb.2023.2123 |
| PMID: | 38378148 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1471-2954 |
|---|---|
| DOI: | 10.1098/rspb.2023.2123 |