دورية أكاديمية
أعرض في EDS

NSAIDs do not prevent exercise-induced performance deficits or alleviate muscle soreness: A placebo-controlled randomized, double-blinded, cross-over study.

التفاصيل البيبلوغرافية
العنوان: NSAIDs do not prevent exercise-induced performance deficits or alleviate muscle soreness: A placebo-controlled randomized, double-blinded, cross-over study.
المؤلفون: Roberts BM; Military Performance Division, US Army Research Institute of Environmental Medicine, USA. Electronic address: Brandon.m.roberts38.mil@health.mil., Sczuroski CE; Military Performance Division, US Army Research Institute of Environmental Medicine, USA., Caldwell AR; Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, USA., Zeppetelli DJ; Military Performance Division, US Army Research Institute of Environmental Medicine, USA., Smith NI; Military Performance Division, US Army Research Institute of Environmental Medicine, USA., Pecorelli VP; Military Performance Division, US Army Research Institute of Environmental Medicine, USA., Gwin JA; Military Nutrition Division, US Army Research Institute of Environmental Medicine, USA., Hughes JM; Military Performance Division, US Army Research Institute of Environmental Medicine, USA., Staab JS; Military Performance Division, US Army Research Institute of Environmental Medicine, USA.
المصدر: Journal of science and medicine in sport [J Sci Med Sport] 2024 May; Vol. 27 (5), pp. 287-292. Date of Electronic Publication: 2024 Feb 13.
نوع المنشور: Journal Article; Randomized Controlled Trial
اللغة: English
بيانات الدورية: Publisher: Elsevier Australia Country of Publication: Australia NLM ID: 9812598 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1861 (Electronic) Linking ISSN: 18781861 NLM ISO Abbreviation: J Sci Med Sport Subsets: MEDLINE
أسماء مطبوعة: Publication: Victoria : Elsevier Australia
Original Publication: Belconnen : Sports Medicine Australia, [1998?-
مواضيع طبية MeSH: Cross-Over Studies* , Myalgia*/prevention & control , Myalgia*/drug therapy , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/therapeutic use , Ibuprofen*/administration & dosage , Ibuprofen*/therapeutic use , Flurbiprofen*/administration & dosage, Humans ; Double-Blind Method ; Adult ; Young Adult ; Male ; Female ; Adolescent ; Athletic Performance/physiology ; Celecoxib/administration & dosage ; Plyometric Exercise ; Heart Rate/drug effects ; Exercise/physiology
مستخلص: Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently consumed by athletes to manage muscle soreness, expedite recovery, or improve performance. Despite the prevalence of NSAID use, their effects on muscle soreness and performance, particularly when administered prophylactically, remain unclear. This randomized, double-blind, counter-balanced, crossover study examined the effect of consuming a single dose of each of three NSAIDs (celecoxib, 200 mg; ibuprofen, 800 mg; flurbiprofen, 100 mg) or placebo 2 h before on muscle soreness and performance following an acute plyometric training session. Twelve healthy adults, aged 18-42 years, completed a standardized plyometric exercise session consisting of 10 sets of 10 repetitions at 40 % 1-repetition maximum (1RM) on a leg press device. During exercise, total work, rating of perceived exertion, and heart rate were measured. Maximum voluntary contraction force (MVC), vertical jump height, and muscle soreness were measured before exercise and 4-h and 24-h post-exercise. We found no significant differences in total work, heart rate, or rating of perceived exertion between treatments. Additionally, no significant differences in muscle soreness or vertical jump were observed between treatments. Ibuprofen and flurbiprofen did not prevent decrements in MVC, but celecoxib attenuated decreases in MVC 4-h post exercise (p < 0.05). This study suggests that athletes may not benefit from prophylactic ibuprofen or flurbiprofen treatment to prevent discomfort or performance decrements associated with exercise, but celecoxib may mitigate short-term performance decrements.
Competing Interests: Declaration of interest statement The authors declare no conflicts of interest.
(Published by Elsevier Ltd.)
فهرسة مساهمة: Keywords: Delayed-onset muscle soreness; Exercise-induced muscle damage; Power; Strength
المشرفين على المادة: 0 (Anti-Inflammatory Agents, Non-Steroidal)
WK2XYI10QM (Ibuprofen)
5GRO578KLP (Flurbiprofen)
JCX84Q7J1L (Celecoxib)
تواريخ الأحداث: Date Created: 20240221 Date Completed: 20240522 Latest Revision: 20240710
رمز التحديث: 20240711
DOI: 10.1016/j.jsams.2024.02.002
PMID: 38383211
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-1861
DOI:10.1016/j.jsams.2024.02.002