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SWOG S1820: A pilot randomized trial of the Altering Intake, Managing Bowel Symptoms Intervention in Survivors of Rectal Cancer.

التفاصيل البيبلوغرافية
العنوان: SWOG S1820: A pilot randomized trial of the Altering Intake, Managing Bowel Symptoms Intervention in Survivors of Rectal Cancer.
المؤلفون: Sun V; Department of Population Sciences, City of Hope, Duarte, California, USA.; Department of Surgery, City of Hope, Duarte, California, USA., Guthrie KA; SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Crane TE; Division of Medical Oncology, Miller School of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, USA., Arnold KB; SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Colby S; SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Freylersythe SG; Division of Medical Oncology, Miller School of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, USA., Braun-Inglis C; University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Topacio R; Cancer Research and Biostatistics, Seattle, Washington, USA., Messick CA; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Carmichael JC; University of California Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, USA., Muskovitz AA; William Beaumont Hospital, Sterling Heights, Michigan, USA., Nashawaty M; Minnesota Oncology (Metro Minnesota Community Oncology Research Consortium), Edina, Minnesota, USA., Bajaj M; Illinois Cancer Care (Heartland Cancer Research NCORP), Peoria, Illinois, USA., Cohen SA; Fred Hutchinson Cancer Center, Seattle, Washington, USA., Flaherty DC; Valley Health Surgical Oncology (Virginia Commonwealth University Massey Cancer Center Minority Underserved NCORP), Winchester, Virginia, USA., O'Rourke MA; Prisma Health Cancer Institute (NCORP of the Carolinas Prisma Health NCORP), Greenville, South Carolina, USA., Jones L; Research Advocate., Krouse RS; Perelman School of Medicine, University of Pennsylvania and the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA., Thomson CA; University of Arizona Cancer Center, Tucson, Arizona, USA.; Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA.
المصدر: Cancer [Cancer] 2024 Jul 01; Vol. 130 (13), pp. 2384-2394. Date of Electronic Publication: 2024 Feb 22.
نوع المنشور: Journal Article; Randomized Controlled Trial
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0142 (Electronic) Linking ISSN: 0008543X NLM ISO Abbreviation: Cancer Subsets: MEDLINE
أسماء مطبوعة: Publication: <2005- >: Hoboken, NJ : Wiley
Original Publication: New York [etc.] Published for the American Cancer Society by J. Wiley [etc.]
مواضيع طبية MeSH: Rectal Neoplasms*/surgery , Cancer Survivors* , Quality of Life*, Humans ; Middle Aged ; Female ; Male ; Pilot Projects ; Aged ; Adult
مستخلص: Background: Survivors of rectal cancer experience persistent bowel dysfunction after treatments. Dietary interventions may be an effective approach for symptom management and posttreatment diet quality. SWOG S1820 was a pilot randomized trial of the Altering Intake, Managing Symptoms in Rectal Cancer (AIMS-RC) intervention for bowel dysfunction in survivors of rectal cancer.
Methods: Ninety-three posttreatment survivors were randomized to the AIMS-RC group (N = 47) or the Healthy Living Education attention control group (N = 46) after informed consent and completion of a prerandomization run-in. Outcome measures were completed at baseline and at 18 and 26 weeks postrandomization. The primary end point was total bowel function score, and exploratory end points included low anterior resection syndrome (LARS) score, quality of life, dietary quality, motivation, self-efficacy, and positive/negative affect.
Results: Most participants were White and college educated, with a mean age of 55.2 years and median time since surgery of 13.1 months. There were no statistically significant differences in total bowel function score by group, with the AIMS-RC group demonstrating statistically significant improvements in the exploratory end points of LARS (p = .01) and the frequency subscale of the bowel function index (p = .03). The AIMS-RC group reported significantly higher acceptability of the study.
Conclusions: SWOG S1820 did not provide evidence of benefit from the AIMS-RC intervention relative to the attention control. Select secondary end points did demonstrate improvements. The study was highly feasible and acceptable for participants in the National Cancer Institute Community Oncology Research Program. Findings provide strong support for further refinement and effectiveness testing of the AIMS-RC intervention.
(© 2024 American Cancer Society.)
References: Clin Colorectal Cancer. 2022 Dec;21(4):325-338. (PMID: 36210321)
J Pers Soc Psychol. 1988 Jun;54(6):1063-70. (PMID: 3397865)
Contemp Clin Trials. 2018 May;68:61-66. (PMID: 29567283)
J Acad Nutr Diet. 2018 Apr;118(4):617-626. (PMID: 28826845)
Br J Surg. 2013 Sep;100(10):1377-87. (PMID: 23939851)
Tech Coloproctol. 2022 Jul;26(7):515-527. (PMID: 35239096)
J Clin Oncol. 2023 Jul 20;41(21):3724-3734. (PMID: 37270691)
J Consult Clin Psychol. 1990 Jun;58(3):310-6. (PMID: 2195084)
Biometrics. 1975 Mar;31(1):103-15. (PMID: 1100130)
Colorectal Dis. 2015 Oct;17(10):908-16. (PMID: 25807963)
Ann Surg. 2014 Apr;259(4):728-34. (PMID: 23598379)
Ann Ital Chir. 2022;93:566-570. (PMID: 36398766)
Qual Life Res. 2017 Jul;26(7):1915-1924. (PMID: 28239781)
Ann Surg. 2022 Jul 1;276(1):46-54. (PMID: 35185131)
Dis Colon Rectum. 2005 Jul;48(7):1353-65. (PMID: 15868235)
J Cancer Surviv. 2023 Jun 6;:. (PMID: 37280309)
J Wound Ostomy Continence Nurs. 2022 Nov-Dec 01;49(6):545-550. (PMID: 36417377)
CA Cancer J Clin. 2012 Jul-Aug;62(4):243-74. (PMID: 22539238)
Am J Epidemiol. 2016 Jul 1;184(1):23-32. (PMID: 27267948)
Nutr Cancer. 2019;71(1):89-99. (PMID: 30572723)
Implement Sci. 2017 Aug 29;12(1):108. (PMID: 28851459)
CA Cancer J Clin. 2006 Sep-Oct;56(5):254-81; quiz 313-4. (PMID: 17005596)
Clin J Oncol Nurs. 2022 Jun 1;26(3):283-292. (PMID: 35604741)
CA Cancer J Clin. 2022 May;72(3):230-262. (PMID: 35294043)
Nutr Cancer. 2017 Feb-Mar;69(2):238-247. (PMID: 28094571)
Dis Colon Rectum. 2022 Oct 1;65(10):1251-1263. (PMID: 34840295)
Oncol Nurs Forum. 2022 Aug 18;49(5):421-431. (PMID: 36067242)
J Cancer Surviv. 2023 Jun;17(3):836-847. (PMID: 36335220)
Contemp Clin Trials. 2016 Jul;49:181-9. (PMID: 27394382)
Colorectal Dis. 2013 Sep;15(9):1130-9. (PMID: 23581977)
Cancer Prev Res (Phila). 2014 Jan;7(1):42-53. (PMID: 24403289)
Qual Life Res. 2014 Dec;23(10):2831-40. (PMID: 24890826)
Curr Colorectal Cancer Rep. 2015;11:37-43. (PMID: 25663833)
Qual Life Res. 2004 Oct;13(8):1445-57. (PMID: 15503840)
Contemp Clin Trials Commun. 2021 Apr 08;22:100768. (PMID: 33997460)
Adv Nutr. 2015 Nov 13;6(6):763-73. (PMID: 26567200)
N Engl J Med. 2023 Jul 27;389(4):322-334. (PMID: 37272534)
CA Cancer J Clin. 2023 Jan;73(1):17-48. (PMID: 36633525)
Ann Surg Oncol. 2015 Dec;22(13):4317-24. (PMID: 26159443)
CA Cancer J Clin. 2022 Sep;72(5):409-436. (PMID: 35736631)
معلومات مُعتمدة: P30 CA023074 United States CA NCI NIH HHS; P30 CA033572 United States CA NCI NIH HHS; R21 CA236057 United States CA NCI NIH HHS; UG1 CA189974 United States CA NCI NIH HHS; Hope Foundation for Cancer Research; P30CA023074 National Cancer Institute/National Institutes of Health; P30CA033572 National Cancer Institute/National Institutes of Health; R21CA236057 National Cancer Institute/National Institutes of Health; UG1CA189974-09 National Cancer Institute/National Institutes of Health
فهرسة مساهمة: Keywords: bowel dysfunction; low anterior resection syndrome (LARS); quality of life; rectal cancer
تواريخ الأحداث: Date Created: 20240222 Date Completed: 20240607 Latest Revision: 20240722
رمز التحديث: 20240723
مُعرف محوري في PubMed: PMC11162313
DOI: 10.1002/cncr.35264
PMID: 38386696
قاعدة البيانات: MEDLINE
الوصف
تدمد:1097-0142
DOI:10.1002/cncr.35264