دورية أكاديمية

Disparities in Acute and Chronic Complications of Diabetes Along the U.S. Rural-Urban Continuum.

التفاصيل البيبلوغرافية
العنوان: Disparities in Acute and Chronic Complications of Diabetes Along the U.S. Rural-Urban Continuum.
المؤلفون: Steiger K; Internal Medicine Residency, Mayo Clinic, Rochester, MN., Herrin J; Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT., Swarna KS; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.; OptumLabs, Eden Prairie, MN., Davis EM; Department of Family and Community Medicine, University of Maryland School of Medicine, Baltimore, MD.; Institute for Health Computing, University of Maryland, Bethesda, MD., McCoy RG; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.; OptumLabs, Eden Prairie, MN.; Institute for Health Computing, University of Maryland, Bethesda, MD.; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
المصدر: Diabetes care [Diabetes Care] 2024 May 01; Vol. 47 (5), pp. 818-825.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE
أسماء مطبوعة: Publication: Alexandria Va : American Diabetes Association
Original Publication: New York, American Diabetes Assn.
مواضيع طبية MeSH: Diabetes Mellitus*/epidemiology , Hyperglycemia* , Myocardial Infarction*/epidemiology , Myocardial Infarction*/etiology , Diabetes Complications* , Stroke* , Hypoglycemia* , Heart Failure*/epidemiology , Heart Failure*/etiology, Adult ; Humans ; Aged ; United States/epidemiology ; Adolescent ; Retrospective Studies ; Medicare
مستخلص: Objective: To determine the relative hazards of acute and chronic diabetes complications among people with diabetes across the U.S. rural-urban continuum.
Research Design and Methods: This retrospective cohort study used the OptumLabs Data Warehouse, a deidentified data set of U.S. commercial and Medicare Advantage beneficiaries, to follow 2,901,563 adults (age ≥18 years) with diabetes between 1 January 2012 and 31 December 2021. We compared adjusted hazard ratios (HRs) of diabetes complications in remote areas (population <2,500), small towns (population 2,500-50,000), and cities (population >50,000).
Results: Compared with residents of cities, residents of remote areas had greater hazards of myocardial infarction (HR 1.06 [95% CI 1.02-1.10]) and revascularization (HR 1.04 [1.02-1.06]) but lower hazards of hyperglycemia (HR 0.90 [0.83-0.98]) and stroke (HR 0.91 [0.88-0.95]). Compared with cities, residents of small towns had greater hazards of hyperglycemia (HR 1.06 [1.02-1.10]), hypoglycemia (HR 1.15 [1.12-1.18]), end-stage kidney disease (HR 1.04 [1.03-1.06]), myocardial infarction (HR 1.10 [1.08-1.12]), heart failure (HR 1.05 [1.03-1.06]), amputation (HR 1.05 [1.02-1.09]), other lower-extremity complications (HR 1.02 [1.01-1.03]), and revascularization (HR 1.05 [1.04-1.06]) but a smaller hazard of stroke (HR 0.95 [0.94-0.97]). Compared with small towns, residents of remote areas had lower hazards of hyperglycemia (HR 0.85 [0.78-0.93]), hypoglycemia (HR 0.92 [0.87-0.97]), and heart failure (HR 0.94 [0.91-0.97]). Hazards of retinopathy and atrial fibrillation/flutter did not vary geographically.
Conclusions: Adults in small towns are disproportionately impacted by complications of diabetes. Future studies should probe for the reasons underlying these disparities.
(© 2024 by the American Diabetes Association.)
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معلومات مُعتمدة: K23 DK114497 United States DK NIDDK NIH HHS; Grant K23DK114497 United States DK NIDDK NIH HHS; Grant K23DK114497 United States DK NIDDK NIH HHS
تواريخ الأحداث: Date Created: 20240222 Date Completed: 20240422 Latest Revision: 20240427
رمز التحديث: 20240427
مُعرف محوري في PubMed: PMC11043221
DOI: 10.2337/dc23-1552
PMID: 38387066
قاعدة البيانات: MEDLINE
الوصف
تدمد:1935-5548
DOI:10.2337/dc23-1552