دورية أكاديمية
Serological screening for celiac disease, by endomysial antibodies, in patients with rheumatoid arthritis.
| العنوان: | Serological screening for celiac disease, by endomysial antibodies, in patients with rheumatoid arthritis. |
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| المؤلفون: | Ghozzi M; Laboratroy of Immunology, Farhat Hached University Hospital, Rue Ibn El Jazzar Sousse Tunisie., Mechi F; Immunologie, University of Monastir, Tunisia., Salem AB; Immunologie, University of Monastir, Tunisia., El Ahmer I; Immunologie, University of Monastir, Tunisia., Mbarki DR; Hematology, Hôpital Sahloul, Tunisia., Melayah S; Laboratroy of Immunology, Farhat Hached University Hospital, Rue Ibn El Jazzar Sousse Tunisie., Mankai A; Laboratroy of Immunology, Farhat Hached University Hospital, Rue Ibn El Jazzar Sousse Tunisie., Ghedira I; Laboratroy of Immunology, Farhat Hached University Hospital, Rue Ibn El Jazzar Sousse Tunisie. |
| المصدر: | Annales de biologie clinique [Ann Biol Clin (Paris)] 2024 Feb 24; Vol. 81 (6), pp. 569-575. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Libbey Eurotext Country of Publication: France NLM ID: 2984690R Publication Model: Print Cited Medium: Internet ISSN: 1950-6112 (Electronic) Linking ISSN: 00033898 NLM ISO Abbreviation: Ann Biol Clin (Paris) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Montrouge : John Libbey Eurotext Original Publication: Paris : Expansion scientifique française. |
| مواضيع طبية MeSH: | Celiac Disease*/diagnosis , Celiac Disease*/epidemiology , Arthritis, Rheumatoid*/diagnosis , Arthritis, Rheumatoid*/epidemiology, Male ; Humans ; Female ; Retrospective Studies ; Immunoglobulin A ; Autoantibodies |
| مستخلص: | Celiac disease (CD) and rheumathoid arthritis (RA) are both multi-factorial chronic inflammatory auto-immune diseases. In this retrospective study, we determined the frequency of CD in patients with RA using IgA anti-endomysial antibodies (EmA) and tried to explain this association. Indirect immunofluorescence on human umbilical cord was used to detect EmA in 215 patients with seropositive RA collected over a 4-year-period. Two thousand and five hundred healthy blood donors (HBD) served as control group. Among the 215 patients with RA, 12 (9 females) were found positive for EmA while only 7 were positive for EmA in control group, EmA are significantly more frequent in RA patients than in HBD (5.58% vs. 0.28%, p < 10-6; 95% CI [8.21-54.01]; odds ratio: 21.05). In RA patients, the frequency of EmA was not statistically different between males and females. The frequency of EmA was significantly higher in female patients than in healthy females (5.32% vs. 0.40%, p < 10-3). Patients with RA can be considered as a high-risk group for CD based on the high frequency of EmA positivity observed in our study. |
| فهرسة مساهمة: | Keywords: anti-endomysial antibodies; celiac disease; rheumatoid arthritis |
| المشرفين على المادة: | 0 (Immunoglobulin A) 0 (Autoantibodies) |
| تواريخ الأحداث: | Date Created: 20240223 Date Completed: 20240226 Latest Revision: 20240226 |
| رمز التحديث: | 20240226 |
| DOI: | 10.1684/abc.2023.1851 |
| PMID: | 38391162 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1950-6112 |
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| DOI: | 10.1684/abc.2023.1851 |