دورية أكاديمية
Electroactive poly(vinylidene fluoride-trifluoroethylene)/graphene composites for cardiac tissue engineering applications.
| العنوان: | Electroactive poly(vinylidene fluoride-trifluoroethylene)/graphene composites for cardiac tissue engineering applications. |
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| المؤلفون: | Meira RM; CF-UM-UP - Physics Centre of Minho and Porto Universities, University of Minho, 4710-057 Braga, Portugal; LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, 4710-057 Braga, Portugal., Ribeiro S; CF-UM-UP - Physics Centre of Minho and Porto Universities, University of Minho, 4710-057 Braga, Portugal; LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, 4710-057 Braga, Portugal., Irastorza I; CF-UM-UP - Physics Centre of Minho and Porto Universities, University of Minho, 4710-057 Braga, Portugal; Cell Biology and Histology Department, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain., Silván U; BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, Spain; IKERBASQUE, Basque Foundation for Science, 48009 Bilbao, Spain., Lanceros-Mendez S; CF-UM-UP - Physics Centre of Minho and Porto Universities, University of Minho, 4710-057 Braga, Portugal; LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, 4710-057 Braga, Portugal; BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, Spain; IKERBASQUE, Basque Foundation for Science, 48009 Bilbao, Spain. Electronic address: senentxu.lanceros@bcmaterials.net., Ribeiro C; CF-UM-UP - Physics Centre of Minho and Porto Universities, University of Minho, 4710-057 Braga, Portugal; LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, 4710-057 Braga, Portugal. Electronic address: cribeiro@fisica.uminho.pt. |
| المصدر: | Journal of colloid and interface science [J Colloid Interface Sci] 2024 Jun; Vol. 663, pp. 73-81. Date of Electronic Publication: 2024 Feb 19. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Orlando, FL : Academic Press Original Publication: New York. |
| مواضيع طبية MeSH: | Graphite* , Fluorocarbon Polymers* , Hydrocarbons, Fluorinated* , Polyvinyls* , Vinyl Compounds*, Tissue Engineering ; Heart |
| مستخلص: | Electroactive materials are increasingly being used in strategies to regenerate cardiac tissue. These materials, particularly those with electrical conductivity, are used to actively recreate the electromechanical nature of the cardiac tissue. In the present work, we describe a novel combination of poly(vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)), a highly electroactive polymer, with graphene (G), exhibiting high electrical conductivity. G/P(VDF-TrFE) films have been characterized in terms of topographical, physico-chemical, mechanical, electrical, and thermal properties, and studied the response of cardiomyocytes adhering to them. The results indicate that the crystallinity and the wettability of the composites remain almost unaffected after G incorporation. In turn, surface roughness, Young modulus, and electric properties are higher in G/P(VDF-TrFE). Finally, the composites are highly biocompatible and able to support cardiomyocyte adhesion and proliferation, particularly surface treated ones, demonstrating the suitability of these materials for cardiac tissue engineering applications. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024. Published by Elsevier Inc.) |
| فهرسة مساهمة: | Keywords: Cardiac tissue engineering; Cell proliferation; Graphene; H9c2(2-1); P(VDF-TrFE); Polarization |
| المشرفين على المادة: | Z2866M3Z1A (trifluoroethene) 7782-42-5 (Graphite) 3C1IX2905B (1,1-difluoroethylene) 24937-79-9 (polyvinylidene fluoride) 0 (Fluorocarbon Polymers) 0 (Hydrocarbons, Fluorinated) 0 (Polyvinyls) 0 (Vinyl Compounds) |
| تواريخ الأحداث: | Date Created: 20240223 Date Completed: 20240322 Latest Revision: 20240322 |
| رمز التحديث: | 20240322 |
| DOI: | 10.1016/j.jcis.2024.02.139 |
| PMID: | 38394819 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1095-7103 |
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| DOI: | 10.1016/j.jcis.2024.02.139 |