دورية أكاديمية
أعرض في EDS

Seroprevalence of Anti-Cytomegalovirus Antibodies in Pregnant Women from South-West Romania.

التفاصيل البيبلوغرافية
العنوان: Seroprevalence of Anti-Cytomegalovirus Antibodies in Pregnant Women from South-West Romania.
المؤلفون: Radoi CL; Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Zlatian O; Medical Laboratory, County Clinical Emergency Hospital of Craiova, 200349 Craiova, Romania.; Microbiology Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Balasoiu M; Medical Laboratory, County Clinical Emergency Hospital of Craiova, 200349 Craiova, Romania.; Microbiology Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Dragomir TL; Department of Internal Medicine I, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania., Sorop MI; Doctoral School, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania., Bagiu IC; Department of Microbiology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.; Multidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), Microbiology Department, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania., Boeriu E; Department of Pediatrics, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania., Susan M; Department of Internal Medicine I, Centre for Preventive Medicine,'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania., Sorop B; Department of Obstetrics and Gynecology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania., Oprisoni LA; Department of Pediatrics, Discipline of Pediatric Oncology and Hematology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania., Iliescu DG; Obstetrics and Gynecology Department, County Clinical Emergency Hospital of Craiova, 200349 Craiova, Romania.; Obstetrics and Gynecology Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
المصدر: Microorganisms [Microorganisms] 2024 Jan 26; Vol. 12 (2). Date of Electronic Publication: 2024 Jan 26.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101625893 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2607 (Print) Linking ISSN: 20762607 NLM ISO Abbreviation: Microorganisms Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2013]-
مستخلص: Cytomegalovirus (CMV), in addition to other agents, is part of the TORCH complex (Toxoplasma gondii, Rubella virus, Cytomegalovirus, Herpes simplex viruses, and other agents). CMV infection is the most frequent cause of congenital malformations. This study aimed to establish the variation of prevalence of anti-CMV antibodies in pregnant women from the South-West region of Romania, according to demographic factors, such as age and area of residence, in two separate time periods (2013-2016 and 2019-2022). We collected from the hospital records the age, place of residence, and anti-CMV antibody test results using immune electrochemiluminescence and chemiluminescence. This study found that the seroprevalence of anti-CMV IgM antibodies increased slightly from 2013-2016 to 2019-2022, from 1.92% to 2.26%, and for IgG antibodies from 93.68% to 94.96%. In both groups was observed a descending trend of anti-CMV IgM seroprevalence with an increase in age, showing a decrease in seroprevalence from 3.57% to 1.09% in pregnant women from rural areas in the 31-35 years age group, while in urban areas, we observed a decrease in seroprevalence from 11.11% to 3.06% in the <20 years age group. The IgG seroprevalence showed an increase both in rural areas (from 93.97% to 95.52%) and urban areas (from 93.52% to 94.27%). In both groups, seroprevalence was higher in rural areas compared to urban regions. These results show a high rate of immunization against CMV in pregnant women in South-West Romania, which led to a low risk of acquiring the primary infection during pregnancy. However, the increase in the rate of primary CMV infections in pregnancy suggests the need for prioritizing screening programs and improving the existing protocols to enhance maternal and child healthcare.
References: Medicina (Kaunas). 2022 Feb 11;58(2):. (PMID: 35208597)
Wien Klin Wochenschr. 2017 Feb;129(3-4):129-135. (PMID: 27599701)
Med Microbiol Immunol. 2010 Feb;199(1):53-60. (PMID: 19949960)
EBioMedicine. 2015 Aug 06;2(9):1205-10. (PMID: 26501119)
Pol J Microbiol. 2017 Jan 2;65(4):425-432. (PMID: 28735326)
BMC Public Health. 2022 Sep 1;22(1):1659. (PMID: 36050659)
J Clin Lab Anal. 1992;6(4):216-8. (PMID: 1328574)
J Clin Microbiol. 2005 Sep;43(9):4713-8. (PMID: 16145132)
Transfus Med. 2017 Aug;27(4):238-248. (PMID: 28643867)
Birth Defects Res. 2017 Mar 15;109(5):336-346. (PMID: 28398680)
J Clin Lab Anal. 2021 Apr;35(4):e23716. (PMID: 33783845)
Clin Vaccine Immunol. 2006 Nov;13(11):1181-4. (PMID: 16957061)
Exp Ther Med. 2020 Sep;20(3):2439-2443. (PMID: 32765730)
Geburtshilfe Frauenheilkd. 1991 Nov;51(11):890-6. (PMID: 1663470)
Clin Infect Dis. 2011 Jan 15;52(2):e11-3. (PMID: 21288834)
J Infect Public Health. 2014 Jul-Aug;7(4):277-88. (PMID: 24629348)
BMC Pregnancy Childbirth. 2016 Mar 15;16:54. (PMID: 26979058)
Med Microbiol Immunol. 2012 Aug;201(3):303-9. (PMID: 22398714)
Clin Vaccine Immunol. 2011 Nov;18(11):1895-9. (PMID: 21918114)
Vaccine. 2019 Nov 28;37(50):7437-7442. (PMID: 29622379)
Healthcare (Basel). 2022 Feb 06;10(2):. (PMID: 35206923)
Ethiop J Health Sci. 2016 Sep;26(5):427-438. (PMID: 28446848)
J Clin Med. 2022 Aug 26;11(17):. (PMID: 36078936)
Bioanalysis. 2009 Aug;1(5):919-35. (PMID: 21083063)
Epidemiol Infect. 2017 May;145(7):1471-1478. (PMID: 28166842)
J Med Virol. 2014 May;86(5):820-6. (PMID: 24114849)
Aust N Z J Obstet Gynaecol. 2016 Feb;56(1):9-18. (PMID: 26391432)
Eur J Clin Microbiol Infect Dis. 2014 Nov;33(11):1951-8. (PMID: 24902519)
Clin Microbiol Rev. 2013 Jan;26(1):86-102. (PMID: 23297260)
Trends Microbiol. 2005 Apr;13(4):164-74. (PMID: 15817386)
Medicina (Kaunas). 2021 Sep 02;57(9):. (PMID: 34577850)
Rev Med Virol. 2007 Jul-Aug;17(4):253-76. (PMID: 17579921)
فهرسة مساهمة: Keywords: antibodies; congenital infections; cytomegalovirus; pregnant women; seroprevalence studies
تواريخ الأحداث: Date Created: 20240224 Latest Revision: 20240227
رمز التحديث: 20240227
مُعرف محوري في PubMed: PMC10893531
DOI: 10.3390/microorganisms12020268
PMID: 38399672
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-2607
DOI:10.3390/microorganisms12020268