دورية أكاديمية
Role of corpus callosum in unconscious vision.
| العنوان: | Role of corpus callosum in unconscious vision. |
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| المؤلفون: | Sanchez-Lopez J; Escuela Nacional de Estudios Superiores Unidad Juriquilla, Universidad Nacional Autonoma de Mexico, Queretaro, Mexico; Department of Neuroscience, Biomedicine and Movement, University of Verona, Italy. Electronic address: javier.sanchezlopez@unam.mx., Cardobi N; Azienda Ospedaliera Universitaria Integrata Verona, Italy. Electronic address: nicolo.cardobi@gmail.com., Parisi G; Department of Neuroscience, Biomedicine and Movement, University of Verona, Italy; Perception and Awareness (PandA) Laboratory, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Italy. Electronic address: giorgia.parisi@univr.it., Savazzi S; Department of Neuroscience, Biomedicine and Movement, University of Verona, Italy; Perception and Awareness (PandA) Laboratory, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Italy. Electronic address: silvia.savazzi@univr.it., Marzi CA; Department of Neuroscience, Biomedicine and Movement, University of Verona, Italy. Electronic address: carloalberto.marzi@univr.it. |
| المصدر: | Neuropsychologia [Neuropsychologia] 2024 Apr 15; Vol. 196, pp. 108839. Date of Electronic Publication: 2024 Feb 23. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Pergamon Press Country of Publication: England NLM ID: 0020713 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3514 (Electronic) Linking ISSN: 00283932 NLM ISO Abbreviation: Neuropsychologia Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford : Pergamon Press Original Publication: Oxford. |
| مواضيع طبية MeSH: | Hemianopsia*/diagnostic imaging , Blindness, Cortical*, Humans ; Corpus Callosum/diagnostic imaging ; Visual Perception ; Unconsciousness ; Photic Stimulation |
| مستخلص: | The existence of unconscious visually triggered behavior in patients with cortical blindness (e.g., homonymous hemianopia) has been amply demonstrated and the neural bases of this phenomenon have been thoroughly studied. However, a crosstalk between the two hemispheres as a possible mechanism of unconscious or partially conscious vision has not been so far considered. Thus, the aim of this study was to assess the relationship between structural and functional properties of the corpus callosum (CC), as shown by probabilistic tractography (PT), behavioral detection/discrimination performance and level of perceptual awareness in the blind field of patients with hemianopia. Twelve patients were tested in two tasks with black-and-white visual square-wave gratings, one task of movement and the other of orientation. The stimuli were lateralized to one hemifield either intact or blind. A PT analysis was carried out on MRI data to extract fiber properties along the CC (genu, body, and splenium). Compared with a control group of participants without brain damage, patients showed lower FA values in all three CC sections studied. For the intact hemifield we found a significant correlation between PT values and visual detection/discrimination accuracy. For the blind hemifield the level of perceptual awareness correlated with PT values for all three CC sections in the movement task. Importantly, significant differences in all three CC sections were found also between patients with above-vs. chance detection/discrimination performance while differences in the genu were found between patients with and without perceptual awareness. Overall, our study provides evidence that the properties of CC fibers are related to the presence of unconscious stimulus detection/discrimination and to hints of perceptual awareness for stimulus presentation to the blind hemifield. These results underline the importance of information exchange between the damaged and the healthy hemisphere for possible partial or full recovery from hemianopia. Competing Interests: Declaration of competing interest None. (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
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| فهرسة مساهمة: | Keywords: Blindsight; Corpus callosum; Hemianopia; Perceptual awareness; Probabilistic tractography; Visual discrimination; Visual movement |
| تواريخ الأحداث: | Date Created: 20240224 Date Completed: 20240325 Latest Revision: 20240627 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC11004727 |
| DOI: | 10.1016/j.neuropsychologia.2024.108839 |
| PMID: | 38401630 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-3514 |
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| DOI: | 10.1016/j.neuropsychologia.2024.108839 |