دورية أكاديمية
Aging of the adrenal gland and its impact on the stress response.
| العنوان: | Aging of the adrenal gland and its impact on the stress response. |
|---|---|
| المؤلفون: | Yiallouris A; Medical Innovation Center (MEDIC), School of Medicine, European University Cyprus, Diogenis Str., Engomi, Nicosia, Cyprus., Filippou C; Medical Innovation Center (MEDIC), School of Medicine, European University Cyprus, Diogenis Str., Engomi, Nicosia, Cyprus., Themistocleous SC; Medical Innovation Center (MEDIC), School of Medicine, European University Cyprus, Diogenis Str., Engomi, Nicosia, Cyprus., Menelaou K; Medical Innovation Center (MEDIC), School of Medicine, European University Cyprus, Diogenis Str., Engomi, Nicosia, Cyprus., Kalodimou V; Medical Innovation Center (MEDIC), School of Medicine, European University Cyprus, Diogenis Str., Engomi, Nicosia, Cyprus., Michaeloudes C; Medical Innovation Center (MEDIC), School of Medicine, European University Cyprus, Diogenis Str., Engomi, Nicosia, Cyprus., Johnson EO; Medical Innovation Center (MEDIC), School of Medicine, European University Cyprus, Diogenis Str., Engomi, Nicosia, Cyprus. Electronic address: E.Johnson@euc.ac.cy. |
| المصدر: | Vitamins and hormones [Vitam Horm] 2024; Vol. 124, pp. 341-366. Date of Electronic Publication: 2024 Feb 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: United States NLM ID: 0413601 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0083-6729 (Print) Linking ISSN: 00836729 NLM ISO Abbreviation: Vitam Horm Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, Academic Press. |
| مواضيع طبية MeSH: | Adrenal Glands* , Hormones*, Humans ; Thyroid Hormones ; Aging |
| مستخلص: | This article discusses the physiological and anatomical changes of adrenal gland with age and the effects this has overall on how the organ responds to stress. Physiological changes entail a decrease in adrenocorticoid hormone secretion however cortisol levels remain intact leading to a disruptive stress response. Additionally, loss of zonation of the organ also occurs. Both characteristics in combination with chronic stress affect overall health. Complex interplay between adrenal aging and stress responsiveness is confounded further by the impact they expel on other systems, such as the thyroid hormone. The body undergoes age-related transformations modifying rate of cellular growth, differentiation, senescence, and hormone production. Given the multiplicity and complexity of hormones, their production must be considered to develop appropriate interventions to mitigate its effect on age related diseases in health. (Copyright © 2024. Published by Elsevier Inc.) |
| المشرفين على المادة: | 0 (Hormones) 0 (Thyroid Hormones) |
| تواريخ الأحداث: | Date Created: 20240226 Date Completed: 20240228 Latest Revision: 20240531 |
| رمز التحديث: | 20240531 |
| DOI: | 10.1016/bs.vh.2023.12.004 |
| PMID: | 38408802 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0083-6729 |
|---|---|
| DOI: | 10.1016/bs.vh.2023.12.004 |