دورية أكاديمية
First and Second Waves of Covid-19: A Comparative Study of the Clinical Presentation and Outcome among Hospitalized Patients in Lagos Nigeria.
| العنوان: | First and Second Waves of Covid-19: A Comparative Study of the Clinical Presentation and Outcome among Hospitalized Patients in Lagos Nigeria. |
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| المؤلفون: | Adejumo OA; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com., Adesola S; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com., Adebayo BI; Department of Community Health and Primary Health Care, Lagos State, University College of Medicine, Ikeja, Lagos, Nigeria., Mutiu WB; Department of Medical Microbiology & Parasitology, Lagos State College of Medicine / Lagos State Biobank, Lagos, Nigeria., Abdus-Salam IA; Department of Epidemiology, Biosecurity & Global Health, Lagos State Ministry of Health., Saka BA; Centre for Biomedical Research Initiatives (CBRI)., Ogunniyan T; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com., Oladokun OD; Department of Anaesthesia, Lagos State University College of Medicine, Ikeja, Lagos State, Nigeria., Oluwadun OB; Department of Anaesthesia, Lagos State University College of Medicine, Ikeja, Lagos State, Nigeria., Bamidele JO; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com., Adetola AV; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com., Osundaro OA; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com., Ogunsakin FO; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com., Agbana EB; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com., Femi-Adebayo T; Department of Community Health and Primary Health Care, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria., Oyadotun OM; Directorate of Medical Services, Lagos State Health Service Commission, Lagos State, Nigeria., Bowale A; Mainland Hospital, Yaba, Lagos State, Nigeria. +2348033502773, oluadejumo75@gmail.com. |
| المصدر: | West African journal of medicine [West Afr J Med] 2024 Jan 31; Vol. 41 (12), pp. 7-15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: West African College Of Physicians And West African College Of Surgeons Country of Publication: Nigeria NLM ID: 8301891 Publication Model: Print Cited Medium: Print ISSN: 0189-160X (Print) Linking ISSN: 0189160X NLM ISO Abbreviation: West Afr J Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Lagos : West African College Of Physicians And West African College Of Surgeons Original Publication: [Yaba, Lagos, Nigeria] : West African College of Physicians and West African College of Surgeons, [1981- |
| مواضيع طبية MeSH: | COVID-19*/diagnosis , COVID-19*/epidemiology, Humans ; Adult ; Middle Aged ; Aged ; Nigeria/epidemiology ; Pandemics ; Retrospective Studies ; Hospitalization |
| مستخلص: | Objective: Nigeria experienced many waves of the COVID-19 pandemic. This study compared the clinical presentations and mortality among hospitalized patients during the first and second waves of the pandemic in Lagos State, Nigeria. Methods: A retrospective cohort study was conducted. Deidentified medical records of laboratory-confirmed COVID-19 patients admitted into 15 isolation centers in Lagos, Nigeria between February 27, 2020, and September 30, 2020 (first wave) and October 1, 2020, and April 30, 2021 (second wave) were reviewed. IBM Statistics version 25 was used for data analysis. Results: More patients were hospitalized during the first wave of the pandemic. The mean age of patients was higher during the second wave (54.5±15.8 years vs. 42.2±15.5 years, p <0.001). More patients admitted during the second wave had comorbidities (56.0% vs 28.6%, p <0.001), were symptomatic (90.8% vs 52.0%, p <0.001), had severe COVID-19 disease (58.9% vs 25%, p <0.001) and died (14.9% vs 6.4%, p<0.001) compared with the first wave. The odds of death increased with age and severity of COVID-19 disease during the first and second waves. Conclusion: A higher proportion of the patients admitted in Lagos, Nigeria during the second wave were older, had comorbidities, and had severe COVID-19 disease than the first wave. Despite the fewer hospitalized patients, there were more deaths during the second wave. Competing Interests: The Authors declare that no competing interest exists. (Copyright © 2024 by West African Journal of Medicine.) |
| فهرسة مساهمة: | Keywords: Clinical Presentation; Covid-19; First Wave; Mortality; Nigeria; Second wave Local Abstract: [Publisher, French] Le Nigeria a connu plusieurs vagues de la pandémie de la COVID-19. Cette étude a comparé les présentations cliniques et la mortalité chez les patients hospitalisés lors des première et deuxième vagues de la pandémie dans l'État de Lagos, Nigeria. [Publisher, French] Une étude de cohorte rétrospective a été réalisée. Les dossiers médicaux déidentifiés des patients atteints de la COVID-19 confirmée par laboratoire, admis dans 15 centres d'isolement à Lagos, Nigeria, entre le 27 février 2020 et le 30 septembre 2020 (première vague) et entre le 1er octobre 2020 et le 30 avril 2021 (deuxième vague), ont été examinés. IBM Statistics version 25 a été utilisé pour l'analyse des données. [Publisher, French] Un plus grand nombre de patients ont été hospitalisés lors de la première vague de la pandémie. L'âge moyen des patients était plus élevé lors de la deuxième vague (54,5±15,8 ans vs. 42,2±15,5 ans, p <0,001). Un plus grand nombre de patients admis lors de la deuxième vague avaient des comorbidités (56,0% vs. 28,6%, p <0,001), étaient symptomatiques (90,8% vs. 52,0%, p <0,001), avaient une forme grave de la maladie à la COVID-19 (58,9% vs. 25%, p <0,001) et sont décédés (14,9% vs. 6,4%, p<0,001) par rapport à la première vague. Les chances de décès ont augmenté avec l'âge et la gravité de la maladie à la COVID-19 lors des première et deuxième vagues. [Publisher, French] Une proportion plus élevée des patients admis à Lagos, Nigeria, lors de la deuxième vague étaient plus âgés, avaient des comorbidités et présentaient une forme grave de la maladie à la COVID-19 par rapport à la première vague. Malgré un nombre moindre de patients hospitalisés, il y a eu plus de décès lors de la deuxième vague. [Publisher, French] Présentation Clinique, Covid-19, Première Vague, Mortalité, Nigeria, Deuxième Vague. |
| تواريخ الأحداث: | Date Created: 20240227 Date Completed: 20240228 Latest Revision: 20240228 |
| رمز التحديث: | 20240228 |
| PMID: | 38411586 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0189-160X |
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